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CAS (CSE1L) signaling pathway in tumor progression and its potential as a biomarker and target for targeted therapy

Tumor biology, 2016-10, Vol.37 (10), p.13077-13090

Jiang, Ming-Chung

2016

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CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells

Molecular carcinogenesis, 2016-11, Vol.55 (11), p.1542-1552

2016

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Correction: Correlations between cytoplasmic CSE1L in neoplastic colorectal glands and depth of tumor penetration and cancer stage

Journal of translational medicine, 2023-05, Vol.21 (1), p.315-315, Article 315

2023

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CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells

Molecular medicine (Cambridge, Mass.), 2012-12, Vol.18 (9), p.1269-1280

2012

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Cellular apoptosis susceptibility (CSE1L/CAS) protein in cancer metastasis and chemotherapeutic drug-induced apoptosis

Journal of experimental & clinical cancer research, 2010-08, Vol.29 (1), p.110-110, Article 110

2010

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Serum Cellular Apoptosis Susceptibility Protein Is a Potential Prognostic Marker for Metastatic Colorectal Cancer

The American journal of pathology, 2010-04, Vol.176 (4), p.1619-1628

2010

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CSE1L modulates Ras-induced cancer cell invasion: correlation of K-Ras mutation and CSE1L expression in colorectal cancer progression

The American journal of surgery, 2013-09, Vol.206 (3), p.418-427

2013

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Increased cellular apoptosis susceptibility (CSE1L/CAS) protein expression promotes protrusion extension and enhances migration of MCF-7 breast cancer cells

Experimental cell research, 2010-10, Vol.316 (17), p.2969-2981

2010

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Differential expression of PTEN and PDCD4 tumor suppressors in melanoma and microRNA-21-positive melanoma cells and squamous carcinoma cells

Dermatologica Sinica, 2019, Vol.37 (1), p.19-27

2019

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The prognostic significance of nuclear CSE1L in urinary bladder urothelial carcinomas

Annals of diagnostic pathology, 2012-10, Vol.16 (5), p.362-368

2012

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Higher Prevalence of Secretory CSE1L/CAS in Sera of Patients with Metastatic Cancer

Cancer epidemiology, biomarkers & prevention, 2009-05, Vol.18 (5), p.1570-1577

2009

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Correlations between cytoplasmic CSE1L in neoplastic colorectal glands and depth of tumor penetration and cancer stage

Journal of translational medicine, 2013-01, Vol.11 (1), p.29-29, Article 29

2013

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CSE1L/CAS, the cellular apoptosis susceptibility protein, enhances invasion and metastasis but not proliferation of cancer cells

Journal of experimental & clinical cancer research, 2008-07, Vol.27 (1), p.15-15, Article 15

2008

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Aspirin Inhibits Matrix Metalloproteinase-2 Activity, Increases E-Cadherin Production, and Inhibits in Vitro Invasion of Tumor Cells

Biochemical and biophysical research communications, 2001-04, Vol.282 (3), p.671-677

2001

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Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines

Nutrition and cancer, 1996, Vol.26 (1), p.111-120

1996

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High nuclear expression of phosphorylated extracellular signal–regulated kinase in tumor cells in colorectal glands is associated with poor outcome in colorectal cancer

Annals of diagnostic pathology, 2013-04, Vol.17 (2), p.165-171

2013

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Clinical-pathological correlation of K-Ras mutation and ERK phosphorylation in colorectal cancer

Polish journal of pathology, 2012-06, Vol.63 (2), p.93-100

2012

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High nuclear phosphorylated extracellular signal-regulated kinase expression associated with poor differentiation, larger tumor size, and an advanced stage of breast cancer

Polish journal of pathology, 2013-10, Vol.64 (3), p.163-169

2013

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Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

Molecular and Cellular Biology, 1995-07, Vol.15 (7), p.3654-3663

1995

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Inverse correlation of phospho-KDR/Flk-1 expression and stage of colorectal cancer: implication of the significance of neoangiogenesis in activated VEGFR-2 expressing early stage colorectal adenocarcinomas

Polish journal of pathology, 2014-10, Vol.65 (3), p.194-201

2014

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CSE1L/CAS, a microtubule-associated protein, inhibits taxol (paclitaxel)-induced apoptosis but enhances cancer cell apoptosis induced by various chemotherapeutic drugs

BMB reports, 2008-03, Vol.41 (3), p.210-216

2008

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Early decline in serum phospho-CSE1L levels in vemurafenib/sunitinib-treated melanoma and sorafenib/lapatinib-treated colorectal tumor xenografts

Journal of translational medicine, 2015-06, Vol.13 (1), p.191-191, Article 191

2015

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High expression of cytoplasmic phosphorylated CSE1L in malignant melanoma but not in benign nevi: phosphorylated CSE1L for the discrimination between melanoma and benign nevi

International journal of clinical and experimental pathology, 2015-01, Vol.8 (2), p.1393-1401

2015

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Function of CSE1L/CAS in the secretion of HT-29 human colorectal cells and its expression in human colon

Molecular and cellular biochemistry, 2009-07, Vol.327 (1-2), p.163-170

2009

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A modified mutation detection method for large-scale cloning of the possible single nucleotide polymorphism sequences

BMB reports, 2005-03, Vol.38 (2), p.191-197

2005

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CAS (CSE1L) signaling pathway in tumor progression and its potential as a biomarker and target for targeted therapy

CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells

Correction: Correlations between cytoplasmic CSE1L in neoplastic colorectal glands and depth of tumor penetration and cancer stage

CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells

Cellular apoptosis susceptibility (CSE1L/CAS) protein in cancer metastasis and chemotherapeutic drug-induced apoptosis

Serum Cellular Apoptosis Susceptibility Protein Is a Potential Prognostic Marker for Metastatic Colorectal Cancer

CSE1L modulates Ras-induced cancer cell invasion: correlation of K-Ras mutation and CSE1L expression in colorectal cancer progression

Increased cellular apoptosis susceptibility (CSE1L/CAS) protein expression promotes protrusion extension and enhances migration of MCF-7 breast cancer cells

Differential expression of PTEN and PDCD4 tumor suppressors in melanoma and microRNA-21-positive melanoma cells and squamous carcinoma cells

The prognostic significance of nuclear CSE1L in urinary bladder urothelial carcinomas

Higher Prevalence of Secretory CSE1L/CAS in Sera of Patients with Metastatic Cancer

Correlations between cytoplasmic CSE1L in neoplastic colorectal glands and depth of tumor penetration and cancer stage

CSE1L/CAS, the cellular apoptosis susceptibility protein, enhances invasion and metastasis but not proliferation of cancer cells

Aspirin Inhibits Matrix Metalloproteinase-2 Activity, Increases E-Cadherin Production, and Inhibits in Vitro Invasion of Tumor Cells

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines

High nuclear expression of phosphorylated extracellular signal–regulated kinase in tumor cells in colorectal glands is associated with poor outcome in colorectal cancer

Clinical-pathological correlation of K-Ras mutation and ERK phosphorylation in colorectal cancer

High nuclear phosphorylated extracellular signal-regulated kinase expression associated with poor differentiation, larger tumor size, and an advanced stage of breast cancer

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

Inverse correlation of phospho-KDR/Flk-1 expression and stage of colorectal cancer: implication of the significance of neoangiogenesis in activated VEGFR-2 expressing early stage colorectal adenocarcinomas

CSE1L/CAS, a microtubule-associated protein, inhibits taxol (paclitaxel)-induced apoptosis but enhances cancer cell apoptosis induced by various chemotherapeutic drugs

Early decline in serum phospho-CSE1L levels in vemurafenib/sunitinib-treated melanoma and sorafenib/lapatinib-treated colorectal tumor xenografts

High expression of cytoplasmic phosphorylated CSE1L in malignant melanoma but not in benign nevi: phosphorylated CSE1L for the discrimination between melanoma and benign nevi

Function of CSE1L/CAS in the secretion of HT-29 human colorectal cells and its expression in human colon

A modified mutation detection method for large-scale cloning of the possible single nucleotide polymorphism sequences

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