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CRISPR-Cas9 Structures and Mechanisms

Annual review of biophysics, 2017-05, Vol.46 (1), p.505-529

2017

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A Cas9-guide RNA complex preorganized for target DNA recognition

Science (American Association for the Advancement of Science), 2015-06, Vol.348 (6242), p.1477-1481

2015

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Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6275), p.867-871

2016

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Nucleosome breathing and remodeling constrain CRISPR-Cas9 function

eLife, 2016-04, Vol.5

2016

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

Science (American Association for the Advancement of Science), 2014-03, Vol.343 (6176), p.1215-1215

2014

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Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

Nature biomedical engineering, 2017, Vol.1 (11), p.889-901

2017

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Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (3), p.596-601

2016

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Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

Nature, 2008-07, Vol.454 (7203), p.523-527

2008

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Structural basis of RNA recognition and activation by innate immune receptor RIG-I

Nature (London), 2011-11, Vol.479 (7373), p.423-427

2011

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Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo

Nature communications, 2018-08, Vol.9 (1), p.3313-12, Article 3313

2018

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Disabling Cas9 by an anti-CRISPR DNA mimic

Science advances, 2017-07, Vol.3 (7), p.e1701620-e1701620

2017

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Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6

EBioMedicine, 2016-07, Vol.9 (C), p.195-206

2016

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The structural biology of CRISPR-Cas systems

Current opinion in structural biology, 2015-02, Vol.30, p.100-111

2015

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Investigation of J-Suppressing Factors in Flat-Rolled \hbox\hbox\hbox\hbox/\hbox Tapes Via Microstructure Analysis

IEEE transactions on applied superconductivity, 2015-06, Vol.25 (3), p.1-5

2015

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Protective humoral responses to severe acute respiratory syndrome-associated coronavirus: implications for the design of an effective protein-based vaccine

Journal of general virology, 2004-10, Vol.85 (10), p.3109-3113

2004

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Temperature-Responsive Competitive Inhibition of CRISPR-Cas9

Molecular cell, 2019-02, Vol.73 (3), p.601-610.e5

2019

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Rapid genotypic antibiotic susceptibility test using CRISPR-Cas12a for urinary tract infection

Analyst (London), 2020-08, Vol.145 (15), p.5226-5231

2020

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The expression of HtrA2 and its diagnostic value in patients with hepatocellular carcinoma

Medicine (Baltimore), 2018-04, Vol.97 (14), p.e0128-e0128

2018

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Electrodeposition of silver nanoparticle arrays on transparent conductive oxides

Applied surface science, 2016-04, Vol.369, p.178-182

2016

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Overexpression of miR-331 Indicates Poor Prognosis and Promotes Progression of Breast Cancer

Oncology research and treatment, 2020-09, Vol.43 (9), p.441-448

2020

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MicroRNA‑20a promotes non‑small cell lung cancer proliferation by upregulating PD‑L1 by targeting PTEN

Oncology letters, 2022-05, Vol.23 (5), p.1, Article 148

2022

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The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection

Nucleic acids research, 2016-01, Vol.44 (2), p.896-909

2016

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Structural and Mechanistic Basis for S elf versus Non‐self RNA discrimination by the Innate Immune Receptor RIG‐I

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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Structure of Human Spindlin1

The Journal of biological chemistry, 2007-01, Vol.282 (1), p.647-656

2007

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Ceftazidime-Avibactam Resistance in Klebsiella pneumoniae Sequence Type II Due to a Mutation in Plasmid-Borne [bla.sub.kpc-2] to [bla.sub.kpc-33], in Henan, China

Infection and drug resistance, 2021-05, Vol.14, p.1725

2021

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CRISPR-Cas9 Structures and Mechanisms

A Cas9-guide RNA complex preorganized for target DNA recognition

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

Nucleosome breathing and remodeling constrain CRISPR-Cas9 function

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo

Disabling Cas9 by an anti-CRISPR DNA mimic

Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6

The structural biology of CRISPR-Cas systems

Investigation of J-Suppressing Factors in Flat-Rolled \hbox\hbox\hbox\hbox/\hbox Tapes Via Microstructure Analysis

Protective humoral responses to severe acute respiratory syndrome-associated coronavirus: implications for the design of an effective protein-based vaccine

Temperature-Responsive Competitive Inhibition of CRISPR-Cas9

Rapid genotypic antibiotic susceptibility test using CRISPR-Cas12a for urinary tract infection

The expression of HtrA2 and its diagnostic value in patients with hepatocellular carcinoma

Electrodeposition of silver nanoparticle arrays on transparent conductive oxides

Overexpression of miR-331 Indicates Poor Prognosis and Promotes Progression of Breast Cancer

MicroRNA‑20a promotes non‑small cell lung cancer proliferation by upregulating PD‑L1 by targeting PTEN

The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection

Structural and Mechanistic Basis for S elf versus Non‐self RNA discrimination by the Innate Immune Receptor RIG‐I

Structure of Human Spindlin1

Ceftazidime-Avibactam Resistance in Klebsiella pneumoniae Sequence Type II Due to a Mutation in Plasmid-Borne [bla.sub.kpc-2] to [bla.sub.kpc-33], in Henan, China

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