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Hydrophobic gating in BK channels

Nature communications, 2018-08, Vol.9 (1), p.3408-8, Article 3408

2018

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Hydrophobic dewetting in gating and regulation of transmembrane protein ion channels

The Journal of chemical physics, 2020-09, Vol.153 (11), p.110901-110901

2020

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Specific PIP2 binding promotes calcium activation of TMEM16A chloride channels

Communications biology, 2021-02, Vol.4 (1), p.1-10, Article 259

2021

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An inner activation gate controls TMEM16F phospholipid scrambling

Nature communications, 2019-04, Vol.10 (1), p.1846-13, Article 1846

2019

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Amyloid assembly is dominated by misregistered kinetic traps on an unbiased energy landscape

Proceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (19), p.10322-10328

2020

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Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A

Nature communications, 2019-08, Vol.10 (1), p.1-12, Article 3769

2019

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Publisher Correction: Hydrophobic gating in BK channels

Nature communications, 2020-09, Vol.11 (1), p.4497-4497, Article 4497

2020

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Enhanced Sampling of Intrinsic Structural Heterogeneity of the BH3-Only Protein Binding Interface of Bcl-xL

The journal of physical chemistry. B, 2017-10, Vol.121 (39), p.9160-9168

2017

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An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening

Nature communications, 2022-11, Vol.13 (1), p.1-13, Article 6784

2022

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Aromatic interactions with membrane modulate human BK channel activation

eLife, 2020-06, Vol.9

2020

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Incorporating physics to overcome data scarcity in predictive modeling of protein function: A case study of BK channels

PLoS computational biology, 2023-09, Vol.19 (9), p.e1011460-e1011460

2023

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Covalent labeling and mass spectrometry reveal subtle higher order structural changes for antibody therapeutics

mAbs, 2019-04, Vol.11 (3), p.463-476

2019

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Activation of TMEM16F by inner gate charged mutations and possible lipid/ion permeation mechanisms

Biophysical journal, 2022-09, Vol.121 (18), p.3445-3457

2022

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Necessity of high-resolution for coarse-grained modeling of flexible proteins

Journal of computational chemistry, 2016-07, Vol.37 (18), p.1725-1733

2016

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Activation of TMEM16F lipid scramblase: transport of ions and lipids

Biophysical journal, 2022-02, Vol.121 (3), p.507a-507a

2022

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Free energy of hydrophobic dewetting in gating of BK channels

Biophysical journal, 2022-02, Vol.121 (3), p.500a-500a

2022

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Inner pore hydration free energy controls the activation of big potassium channels

Biophysical journal, 2023-04, Vol.122 (7), p.1158-1167

2023

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Small Molecule NS11021 Promotes BK Channel Activation by Increasing Inner Pore Hydration

Journal of chemical information and modeling, 2024-10, Vol.64 (19), p.7616-7625

2024

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A predictive model of voltage gating of BK channels via physical modeling and machine learning

Biophysical journal, 2023-02, Vol.122 (3), p.388a-388a

2023

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Intrinsic opening of BK channels derives from the leakage of hydrophobic gating

Biophysical journal, 2022-02, Vol.121 (3), p.500a-500a

2022

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Clean synthesis of propylene carbonate from urea and 1,2-propylene glycol over zinc-iron double oxide catalyst

Journal of chemical technology and biotechnology (1986), 2006-05, Vol.81 (5), p.794-798

2006

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Specific PIP 2 binding promotes calcium activation of TMEM16A chloride channels

Communications biology, 2021-02, Vol.4 (1), p.259

2021

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Necessity of High Physical Resolution in the Development of Flexible Coarse-Grained Protein Models

Biophysical journal, 2015-01, Vol.108 (2), p.161a-161a

2015

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The Road not Taken - Lipid/Ion Conduction Pathways in TMEM16 Protein Family

Biophysical journal, 2020-02, Vol.118 (3), p.267a-267a

2020

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The Levinthal Problem in Amyloid Aggregation: Identification of Good Coordinates in a Flat Reaction Space

Biophysical journal, 2017-02, Vol.112 (3), p.198a-198a

2017

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Hydrophobic gating in BK channels

Hydrophobic dewetting in gating and regulation of transmembrane protein ion channels

Specific PIP2 binding promotes calcium activation of TMEM16A chloride channels

An inner activation gate controls TMEM16F phospholipid scrambling

Amyloid assembly is dominated by misregistered kinetic traps on an unbiased energy landscape

Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A

Publisher Correction: Hydrophobic gating in BK channels

Enhanced Sampling of Intrinsic Structural Heterogeneity of the BH3-Only Protein Binding Interface of Bcl-xL

An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening

Aromatic interactions with membrane modulate human BK channel activation

Incorporating physics to overcome data scarcity in predictive modeling of protein function: A case study of BK channels

Covalent labeling and mass spectrometry reveal subtle higher order structural changes for antibody therapeutics

Activation of TMEM16F by inner gate charged mutations and possible lipid/ion permeation mechanisms

Necessity of high-resolution for coarse-grained modeling of flexible proteins

Activation of TMEM16F lipid scramblase: transport of ions and lipids

Free energy of hydrophobic dewetting in gating of BK channels

Inner pore hydration free energy controls the activation of big potassium channels

Small Molecule NS11021 Promotes BK Channel Activation by Increasing Inner Pore Hydration

A predictive model of voltage gating of BK channels via physical modeling and machine learning

Intrinsic opening of BK channels derives from the leakage of hydrophobic gating

Clean synthesis of propylene carbonate from urea and 1,2-propylene glycol over zinc-iron double oxide catalyst

Specific PIP 2 binding promotes calcium activation of TMEM16A chloride channels

Necessity of High Physical Resolution in the Development of Flexible Coarse-Grained Protein Models

The Road not Taken - Lipid/Ion Conduction Pathways in TMEM16 Protein Family

The Levinthal Problem in Amyloid Aggregation: Identification of Good Coordinates in a Flat Reaction Space

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