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Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes

Nature immunology, 2020-10, Vol.21 (10), p.1244-1255

2020

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Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture

Nature communications, 2023-02, Vol.14 (1), p.768-768, Article 768

2023

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Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis

Nature metabolism, 2020-05, Vol.2 (5), p.413-431

2020

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Major adverse cardiovascular events in people with chronic kidney disease in relation to disease severity and diabetes status

PloS one, 2019-08, Vol.14 (8), p.e0221044-e0221044

2019

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Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.19760-19772

2013

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Expression of high-affinity human antibody fragments in bacteria

Nature protocols, 2012-02, Vol.7 (2), p.364-373

2012

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Glucagon and exenatide improve contractile recovery following ischaemia/reperfusion in the isolated perfused rat heart

Physiological reports, 2023-03, Vol.11 (6), p.e15597-n/a

2023

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A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties

PloS one, 2016-12, Vol.11 (12), p.e0167935-e0167935

2016

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Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type

Molecular cancer, 2013-02, Vol.12 (1), p.11-11

2013

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Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease

PloS one, 2014-08, Vol.9 (8), p.e104001

2014

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A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

The Journal of immunology (1950), 2017-01, Vol.198 (1), p.528-537

2017

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Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression

mAbs, 2013-03, Vol.5 (2), p.255-262

2013

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Tailoring in vitro Evolution for Protein Affinity or Stability

Proceedings of the National Academy of Sciences - PNAS, 2001-01, Vol.98 (1), p.75-80

2001

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The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics

mAbs, 2013-11, Vol.5 (6), p.851-859

2013

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Effects of Cotadutide on Metabolic and Hepatic Parameters in Adults With Overweight or Obesity and Type 2 Diabetes: A 54-Week Randomized Phase 2b Study

Diabetes care, 2021-06, Vol.44 (6), p.1433-1442

2021

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Unbinding Forces of Single Antibody-Antigen Complexes Correlate with Their Thermal Dissociation Rates

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (18), p.9972-9977

2000

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Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

The Journal of immunology (1950), 2017-09, Vol.199 (5), p.1943-1943

2017

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cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20251-20256

2008

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Challenges and opportunities for non-antibody scaffold drugs

Drug discovery today, 2015-10, Vol.20 (10), p.1271-1283

2015

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Meet Our Editorial Board Member

Current pharmaceutical biotechnology, 2015-10, Vol.17 (1), p.1-1

Jermutus, Lutz

2015

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Ribosome display: an in vitro method for selection and evolution of antibodies from libraries

Journal of immunological methods, 1999-12, Vol.231 (1), p.119-135

1999

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Ribosome Display Efficiently Selects and Evolves High-Affinity Antibodies in vitro from Immune Libraries

Proceedings of the National Academy of Sciences - PNAS, 1998-11, Vol.95 (24), p.14130-14135

1998

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Probing a Protein-Protein Interaction by in vitro Evolution

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7619-7624

2006

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Isolation of a Small-Molecule Inhibitor of the Antiapoptotic Protein Bcl-xL from a DNA-Encoded Chemical Library

ChemMedChem, 2010-04, Vol.5 (4), p.584-590

2010

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Selection of hapten-specific single-domain antibodies from a non-immunized llama ribosome display library

Journal of immunological methods, 2003-10, Vol.281 (1), p.161-175

2003

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Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes

Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture

Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis

Major adverse cardiovascular events in people with chronic kidney disease in relation to disease severity and diabetes status

Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor

Expression of high-affinity human antibody fragments in bacteria

Glucagon and exenatide improve contractile recovery following ischaemia/reperfusion in the isolated perfused rat heart

A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties

Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type

Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression

Tailoring in vitro Evolution for Protein Affinity or Stability

The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics

Effects of Cotadutide on Metabolic and Hepatic Parameters in Adults With Overweight or Obesity and Type 2 Diabetes: A 54-Week Randomized Phase 2b Study

Unbinding Forces of Single Antibody-Antigen Complexes Correlate with Their Thermal Dissociation Rates

Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions

Challenges and opportunities for non-antibody scaffold drugs

Meet Our Editorial Board Member

Ribosome display: an in vitro method for selection and evolution of antibodies from libraries

Ribosome Display Efficiently Selects and Evolves High-Affinity Antibodies in vitro from Immune Libraries

Probing a Protein-Protein Interaction by in vitro Evolution

Isolation of a Small-Molecule Inhibitor of the Antiapoptotic Protein Bcl-xL from a DNA-Encoded Chemical Library

Selection of hapten-specific single-domain antibodies from a non-immunized llama ribosome display library

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