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PDK4 Deficiency Suppresses Hepatic Glucagon Signaling by Decreasing cAMP Levels

Diabetes (New York, N.Y.), 2018-10, Vol.67 (10), p.2054-2068

2018

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Pyruvate Dehydrogenase Complex Activity Controls Metabolic and Malignant Phenotype in Cancer Cells

The Journal of biological chemistry, 2008-08, Vol.283 (33), p.22700-22708

2008

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Cuban Policosanol Prevents the Apoptosis and the Mitochondrial Dysfunction Induced by Lipopolysaccharide in C2C12 Myoblast via Activation of Akt and Erk Pathways

Journal of Nutritional Science and Vitaminology, 2022/04/30, Vol.68(2), pp.79-86

2022

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Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers

Diabetes and Metabolism Journal, 2015, 39(3), 149, pp.188-197

Jeoung, Nam Ho

2015

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Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet

Biochemical journal, 2009-10, Vol.423 (2), p.243-252

2009

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Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation

Biochemical journal, 2006-08, Vol.397 (3), p.417-425

2006

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Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy

American journal of physiology. Heart and circulatory physiology, 2008-02, Vol.294 (2), p.H936-H943

2008

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Carbohydrate-response Element-binding Protein Deletion Alters Substrate Utilization Producing an Energy-deficient Liver

The Journal of biological chemistry, 2008-01, Vol.283 (3), p.1670-1678

2008

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Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice

American journal of physiology: endocrinology and metabolism, 2008-07, Vol.295 (1), p.E46-E54

2008

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Physiological effect and therapeutic application of alpha lipoic acid

Current medicinal chemistry, 2014-01, Vol.21 (32), p.3636

2014

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Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis

Diabetes (New York, N.Y.), 2016-10, Vol.65 (10), p.2876-2887

2016

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Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation

Scientific reports, 2015-11, Vol.5 (1), p.16577-16577, Article 16577

2015

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Transcriptional regulation of pyruvate dehydrogenase kinase

Diabetes and Metabolism Journal, 2012, 36(5), 133, pp.328-335

2012

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Targeted Disruption of ROCK1 Causes Insulin Resistance in Vivo

The Journal of biological chemistry, 2009-05, Vol.284 (18), p.11776-11780

2009

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Overview of the molecular and biochemical basis of branched-chain amino acid catabolism

The Journal of nutrition, 2005-06, Vol.135 (6 Suppl), p.1527S-1530S

2005

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Fasting induces ketoacidosis and hypothermia in PDHK2/PDHK4-double-knockout mice

Biochemical journal, 2012-05, Vol.443 (3), p.829-839

2012

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Dimethylfumarate suppresses adipogenic differentiation in 3T3-L1 preadipocytes through inhibition of STAT3 activity

PloS one, 2013-04, Vol.8 (4), p.e61411

2013

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Loss or Silencing of the PHD1 Prolyl Hydroxylase Protects Livers of Mice Against Ischemia/Reperfusion Injury

Gastroenterology (New York, N.Y. 1943), 2010-03, Vol.138 (3), p.1143-1154.e2

2010

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Mechanisms responsible for regulation of branched-chain amino acid catabolism

Biochemical and biophysical research communications, 2004-01, Vol.313 (2), p.391-396

2004

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Activation of NAD(P)H:Quinone Oxidoreductase 1 Prevents Arterial Restenosis by Suppressing Vascular Smooth Muscle Cell Proliferation

Circulation research, 2009-04, Vol.104 (7), p.842-850

2009

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Metformin Inhibits Growth Hormone―Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner

Diabetes (New York, N.Y.), 2012-10, Vol.61 (10), p.2484-2494

2012

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Pyruvate dehydrogenase kinase-4 contributes to the recirculation of gluconeogenic precursors during postexercise glycogen recovery

American journal of physiology. Regulatory, integrative and comparative physiology, 2014-01, Vol.306 (2), p.R102-R107

2014

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Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells

Arteriosclerosis, thrombosis, and vascular biology, 2009-10, Vol.29 (10), p.1558

2009

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Dimethylfumarate attenuates restenosis after acute vascular injury by cell-specific and Nrf2-dependent mechanisms

Redox biology, 2014-01, Vol.2 (C), p.855-864

2014

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Impaired growth and neurological abnormalities in branched-chain alpha-keto acid dehydrogenase kinase-deficient mice

Biochemical journal, 2006-11, Vol.400 (1), p.153-162

2006

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PDK4 Deficiency Suppresses Hepatic Glucagon Signaling by Decreasing cAMP Levels

Pyruvate Dehydrogenase Complex Activity Controls Metabolic and Malignant Phenotype in Cancer Cells

Cuban Policosanol Prevents the Apoptosis and the Mitochondrial Dysfunction Induced by Lipopolysaccharide in C2C12 Myoblast via Activation of Akt and Erk Pathways

Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers

Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet

Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation

Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy

Carbohydrate-response Element-binding Protein Deletion Alters Substrate Utilization Producing an Energy-deficient Liver

Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice

Physiological effect and therapeutic application of alpha lipoic acid

Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis

Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation

Transcriptional regulation of pyruvate dehydrogenase kinase

Targeted Disruption of ROCK1 Causes Insulin Resistance in Vivo

Overview of the molecular and biochemical basis of branched-chain amino acid catabolism

Fasting induces ketoacidosis and hypothermia in PDHK2/PDHK4-double-knockout mice

Dimethylfumarate suppresses adipogenic differentiation in 3T3-L1 preadipocytes through inhibition of STAT3 activity

Loss or Silencing of the PHD1 Prolyl Hydroxylase Protects Livers of Mice Against Ischemia/Reperfusion Injury

Mechanisms responsible for regulation of branched-chain amino acid catabolism

Activation of NAD(P)H:Quinone Oxidoreductase 1 Prevents Arterial Restenosis by Suppressing Vascular Smooth Muscle Cell Proliferation

Metformin Inhibits Growth Hormone―Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner

Pyruvate dehydrogenase kinase-4 contributes to the recirculation of gluconeogenic precursors during postexercise glycogen recovery

Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells

Dimethylfumarate attenuates restenosis after acute vascular injury by cell-specific and Nrf2-dependent mechanisms

Impaired growth and neurological abnormalities in branched-chain alpha-keto acid dehydrogenase kinase-deficient mice

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