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Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts

Molecular cell, 2016-11, Vol.64 (3), p.520-533

2016

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The Human Nuclear Exosome Targeting Complex Is Loaded onto Newly Synthesized RNA to Direct Early Ribonucleolysis

Cell reports (Cambridge), 2015-01, Vol.10 (2), p.178-192

2015

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Nuclear stability and transcriptional directionality separate functionally distinct RNA species

Nature communications, 2014-11, Vol.5 (1), p.5336-5336, Article 5336

2014

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Controlling nuclear RNA levels

Nature reviews. Genetics, 2018-08, Vol.19 (8), p.518

2018

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Interaction Profiling Identifies the Human Nuclear Exosome Targeting Complex

Molecular cell, 2011-08, Vol.43 (4), p.624-637

2011

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Dealing with Pervasive Transcription

Molecular cell, 2013-11, Vol.52 (4), p.473-484

2013

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The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

Nature communications, 2019-07, Vol.10 (1), p.3393-11, Article 3393

2019

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Mapping domains of ARS2 critical for its RNA decay capacity

Nucleic acids research, 2020-07, Vol.48 (12), p.6943

2020

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Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex

Cell reports (Cambridge), 2024-01, Vol.43 (1), p.113639-113639, Article 113639

2024

Volltextzugriff (PDF)

The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production

Cell reports (Cambridge), 2015-07, Vol.12 (1), p.128-139

2015

Volltextzugriff (PDF)

Nuclear sorting of RNA

Wiley interdisciplinary reviews. RNA, 2020-03, Vol.11 (2), p.e1572-n/a

2020

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Escaping nuclear decay: the significance of mRNA export for gene expression

Current genetics, 2019-04, Vol.65 (2), p.473-476

2019

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Nuclear Retention Prevents Premature Cytoplasmic Appearance of mRNA

Molecular cell, 2012-10, Vol.48 (1), p.145-152

2012

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Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes

Genes & development, 2014-11, Vol.28 (22), p.2498-2517

2014

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Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage

RNA biology, 2017-07, Vol.14 (7), p.820-826

2017

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Rapid factor depletion highlights intricacies of nucleoplasmic RNA degradation

Nucleic acids research, 2022-02, Vol.50 (3), p.1583

2022

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Assigning function to an unexplored Integrator module

Molecular cell, 2024-07, Vol.84 (13), p.2405-2406

2024

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Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome

Molecular cell, 2022-07, Vol.82 (13), p.2505-2518.e7

2022

Volltextzugriff (PDF)

The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay

Nucleic acids research, 2020-03, Vol.48 (5), p.2518

2020

Volltextzugriff (PDF)

ARS2/SRRT: at the nexus of RNA polymerase II transcription, transcript maturation and quality control

Biochemical Society transactions, 2021-06, Vol.49 (3), p.1325

2021

Volltextzugriff (PDF)

RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters

Science (American Association for the Advancement of Science), 2008-12, Vol.322 (5909), p.1851-1854

2008

Volltextzugriff (PDF)

Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA

The EMBO journal, 2013-07, Vol.32 (13), p.1855-1868

2013

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Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae

Nature communications, 2021-08, Vol.12 (1), p.4951-4951, Article 4951

2021

Volltextzugriff (PDF)

Diminished nuclear RNA decay upon Salmonella infection upregulates antibacterial noncoding RNAs

The EMBO journal, 2018-07, Vol.37 (13), p.n/a

2018

Volltextzugriff (PDF)

Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality

Nature structural & molecular biology, 2013-08, Vol.20 (8), p.923

2013

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Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts

The Human Nuclear Exosome Targeting Complex Is Loaded onto Newly Synthesized RNA to Direct Early Ribonucleolysis

Nuclear stability and transcriptional directionality separate functionally distinct RNA species

Controlling nuclear RNA levels

Interaction Profiling Identifies the Human Nuclear Exosome Targeting Complex

Dealing with Pervasive Transcription

The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

Mapping domains of ARS2 critical for its RNA decay capacity

Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex

The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production

Nuclear sorting of RNA

Escaping nuclear decay: the significance of mRNA export for gene expression

Nuclear Retention Prevents Premature Cytoplasmic Appearance of mRNA

Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes

Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage

Rapid factor depletion highlights intricacies of nucleoplasmic RNA degradation

Assigning function to an unexplored Integrator module

Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome

The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay

ARS2/SRRT: at the nexus of RNA polymerase II transcription, transcript maturation and quality control

RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters

Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA

Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae

Diminished nuclear RNA decay upon Salmonella infection upregulates antibacterial noncoding RNAs

Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality

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