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Implant‐associated osteomyelitis: Development, characterisation, and application of a porcine model

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2021-04, Vol.129 (S141), p.1-44

Jensen, Louise Kruse

2021

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Bacterial micro-aggregates as inoculum in animal models of implant-associated infections

Biofilm, 2024-06, Vol.7, p.100200-100200, Article 100200

2024

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Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli

Scientific reports, 2023-07, Vol.13 (1), p.12404-12404, Article 12404

2023

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The inflammatory response to bone infection – a review based on animal models and human patients

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2020-04, Vol.128 (4), p.275-286

2020

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Fibrinolytic and antibiotic treatment of prosthetic vascular graft infections in a novel rat model

PloS one, 2023-07, Vol.18 (7), p.e0287671-e0287671

2023

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Bacterial invasion of the submicron osteocyte lacuna–canaliculi network (OLCN): a part of osteomyelitis disease biology

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2023-07, Vol.131 (7), p.325-332

2023

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Rifampicin does not reduce moxifloxacin concentrations at the site of infection and may not improve treatment outcome of a one-stage exchange surgery protocol of implant-associated osteomyelitis lesions in a porcine model

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2024-03, Vol.132 (3), p.198-209

2024

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Pigs are useful for the molecular study of bone inflammation and regeneration in humans

Laboratory animals (London), 2018-12, Vol.52 (6), p.630-640

2018

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In memoriam Elisabeth Ralfkiær 30.10.1950–11.07.2020

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2020-10, Vol.128 (10), p.541-542

2020

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First hip hemiarthroplasty in a Göttingen Minipig; surgical and post-mortem protocol

Journal of orthopaedic surgery and research, 2024-09, Vol.19 (1), p.549-13, Article 549

2024

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Synthesis of the cyanobacterial halometabolite Chlorosphaerolactylate B and demonstration of its antimicrobial effect in vitro and in vivo

Frontiers in microbiology, 2022-09, Vol.13, p.950855-950855

2022

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Catheter‐associated bladder mucosal trauma during intermittent voiding: An experimental study in pigs

BJUI compass, 2024-03, Vol.5 (2), p.217-223

2024

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Inflammatory proteins in infected bone tissue – An explorative porcine study

Bone Reports, 2020-12, Vol.13, p.100292-100292, Article 100292

2020

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Intraoperative tissue sampling for histology in chronic osteomyelitis shows high neutrophil infiltration centrally and low remains in debrided presumed infection-free regions

Injury, 2024-02, Vol.55 (2), p.111178-111178, Article 111178

2024

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Bladder catheterization improves bacterial interference with asymptomatic Escherichia coli 83972 in an experimental porcine model of urinary tract infection

The Journal of infectious diseases, 2024-08

2024

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In Vivo Gentamicin Susceptibility Test for Prevention of Bacterial Biofilms in Bone Tissue and on Implants

Antimicrobial agents and chemotherapy, 2019-02, Vol.63 (2)

2019

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Eradication of Staphylococcus aureus in Implant-Associated Osteomyelitis by an Injectable In Situ-Forming Depot Antibiotics Delivery System

The Journal of infectious diseases, 2024-09, Vol.230 (3), p.614-623

2024

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Single‐dose bone pharmacokinetics of vancomycin in a porcine implant‐associated osteomyelitis model

Journal of orthopaedic research, 2018-04, Vol.36 (4), p.1093-1098

2018

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Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model

Journal of bone and joint surgery. American volume, 2016-03, Vol.98 (5), p.363-369

2016

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Novel porcine model of implant‐associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response

Journal of orthopaedic research, 2017-10, Vol.35 (10), p.2211-2221

2017

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Early implant‐associated osteomyelitis results in a peri‐implanted bacterial reservoir

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2017-01, Vol.125 (1), p.38-45

2017

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The host response to bacterial bone infection involves a local upregulation of several acute phase proteins

Immunobiology (1979), 2020-05, Vol.225 (3), p.151914-151914, Article 151914

2020

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Specific Antibodies to Staphylococcus aureus Biofilm Are Present in Serum from Pigs with Osteomyelitis

In vivo (Athens), 2015-09, Vol.29 (5), p.555-560

2015

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Coating of bone implants with silica, hyperbranched polyethyleneimine, and gentamicin prevents development of osteomyelitis in a porcine model

Materialia, 2022-08, Vol.24, p.101473, Article 101473

2022

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Whole-Genome Sequence of Staphylococcus aureus S54F9 Isolated from a Chronic Disseminated Porcine Lung Abscess and Used in Human Infection Models

Genome announcements (Washington, DC), 2015-10, Vol.3 (5)

2015

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Implant‐associated osteomyelitis: Development, characterisation, and application of a porcine model

Bacterial micro-aggregates as inoculum in animal models of implant-associated infections

Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli

The inflammatory response to bone infection – a review based on animal models and human patients

Fibrinolytic and antibiotic treatment of prosthetic vascular graft infections in a novel rat model

Bacterial invasion of the submicron osteocyte lacuna–canaliculi network (OLCN): a part of osteomyelitis disease biology

Rifampicin does not reduce moxifloxacin concentrations at the site of infection and may not improve treatment outcome of a one-stage exchange surgery protocol of implant-associated osteomyelitis lesions in a porcine model

Pigs are useful for the molecular study of bone inflammation and regeneration in humans

In memoriam Elisabeth Ralfkiær 30.10.1950–11.07.2020

First hip hemiarthroplasty in a Göttingen Minipig; surgical and post-mortem protocol

Synthesis of the cyanobacterial halometabolite Chlorosphaerolactylate B and demonstration of its antimicrobial effect in vitro and in vivo

Catheter‐associated bladder mucosal trauma during intermittent voiding: An experimental study in pigs

Inflammatory proteins in infected bone tissue – An explorative porcine study

Intraoperative tissue sampling for histology in chronic osteomyelitis shows high neutrophil infiltration centrally and low remains in debrided presumed infection-free regions

Bladder catheterization improves bacterial interference with asymptomatic Escherichia coli 83972 in an experimental porcine model of urinary tract infection

In Vivo Gentamicin Susceptibility Test for Prevention of Bacterial Biofilms in Bone Tissue and on Implants

Eradication of Staphylococcus aureus in Implant-Associated Osteomyelitis by an Injectable In Situ-Forming Depot Antibiotics Delivery System

Single‐dose bone pharmacokinetics of vancomycin in a porcine implant‐associated osteomyelitis model

Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model

Novel porcine model of implant‐associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response

Early implant‐associated osteomyelitis results in a peri‐implanted bacterial reservoir

The host response to bacterial bone infection involves a local upregulation of several acute phase proteins

Specific Antibodies to Staphylococcus aureus Biofilm Are Present in Serum from Pigs with Osteomyelitis

Coating of bone implants with silica, hyperbranched polyethyleneimine, and gentamicin prevents development of osteomyelitis in a porcine model

Whole-Genome Sequence of Staphylococcus aureus S54F9 Isolated from a Chronic Disseminated Porcine Lung Abscess and Used in Human Infection Models

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