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Pharmacokinetics of Otamixaban, a Direct Factor Xa Inhibitor, in Healthy Male Subjects: Pharmacokinetic Model Development for Phase 2/3 Simulation of Exposure

Journal of clinical pharmacology, 2006-01, Vol.46 (1), p.37-44

2006

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Pharmacokinetics and Concentration-Effect Analysis of Intravenous RGD891, a Platelet GPIIb/IIIa Antagonist, Using Mixed-Effects Modeling (NONMEM)

Journal of clinical pharmacology, 2000-10, Vol.40 (10), p.1129-1140

2000

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Pharmacokinetic/Pharmacodynamic Relationships for Otamixaban, a Direct Factor Xa Inhibitor, in Healthy Subjects

Journal of clinical pharmacology, 2006-01, Vol.46 (1), p.45-51

2006

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The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: A case study with fexofenadine hydrochloride

Biopharmaceutics & drug disposition, 2004-12, Vol.25 (9), p.373-387

2004

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Pharmacokinetics, pharmacodynamics, and safety of a lipid-lowering adenosine A1 agonist, RPR749, in healthy subjects

American journal of therapeutics, 2004-05, Vol.11 (3), p.175-189

2004

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Effect of Food on Pharmacokinetics of an Inhaled Drug: A Case Study with a VLA-4 Antagonist, HMR1031

Journal of clinical pharmacology, 2003-12, Vol.43 (12), p.1341-1349

2003

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A Mass Balance Study to Evaluate the Biotransformation and Excretion of [14C]-Triamcinolone Acetonide following Oral Administration

Journal of clinical pharmacology, 2000-07, Vol.40 (7), p.770-780

2000

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Estimating Mass Balance for Inhaled Drugs in Humans: An Example with a VLA-4 Antagonist, IVL745

Journal of clinical pharmacology, 2004-04, Vol.44 (4), p.348-358

2004

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Pharmacokinetic-Pharmacodynamic Modeling of the Antilipolytic Effects of an Adenosine Receptor Agonist in Healthy Volunteers

Journal of clinical pharmacology, 2001-01, Vol.41 (1), p.61-69

2001

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Pharmacokinetics of M100240 and MDL 100,173, a Dual Angiotensin-Converting Enzyme/Neutral Endopeptidase Inhibitor, in Healthy Young and Elderly Volunteers

Journal of clinical pharmacology, 2004-08, Vol.44 (8), p.901-905

2004

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Pharmacoscintigraphic comparison of HMR 1031, a VLA-4 antagonist, in healthy volunteers following delivery via a nebulizer and a dry powder inhaler

American journal of therapeutics, 2004-03, Vol.11 (2), p.103-113

2004

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Mass balance study of [14C]M100240, a dual angiotensin-converting enzyme/neutral endopeptidase inhibitor, in healthy male subjects

American journal of therapeutics, 2003-09, Vol.10 (5), p.356-362

2003

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Pharmacokinetics, Pharmacodynamics, and Safety of a Platelet GPIIb/IIIa Antagonist, RGD891, following Intravenous Administration in Healthy Male Volunteers

Journal of clinical pharmacology, 2000-11, Vol.40 (11), p.1245-1256

2000

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Pharmacokinetics, Safety, and Tolerability of Single Intravenous Infusions of an Adenosine Agonist, AMP 579, in Healthy Male Volunteers

Journal of clinical pharmacology, 1999-10, Vol.39 (10), p.1044-1052

1999

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Pharmacokinetics and Safety of Single Intravenous Infusions of the Adenosine Agonist, AMP 579, in Patients with End-Stage Renal Insufficiency

Journal of clinical pharmacology, 2000-07, Vol.40 (7), p.745-751

2000

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Population pharmacokinetics/pharmacodynamics of ciclesonide

Journal of allergy and clinical immunology, 2002, Vol.109 (1), p.S236-S236

2002

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First report of an intravenous and oral glycoprotein IIb/IIIa inhibitor (RPR 109891) in patients with recent acute coronary syndromes: Results of the TIMI 15A and 15B trials

The American heart journal, 2000-07, Vol.140 (1), p.81-92

2000

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Negligible Systemic Absorption of Topical Isotretinoin Cream: Implications for Teratogenicity

Journal of clinical pharmacology, 1997-04, Vol.37 (4), p.279-284

1997

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THE PHARMACOKINETICS AND PHARMACODYNAMICS OF DESMOPRESSIN: EFFECT ON PLASMA FACTOR VIII

American journal of therapeutics, 1997-01, Vol.4 (1), p.3-8

1997

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Effects of food on the pharmacokinetics of sparfloxacin

Clinical therapeutics, 1999-06, Vol.21 (6), p.982-991

1999

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Pharmacokinetics, Safety, and Tolerability of Single Intravenous Infusions of an Adenosine Agonist, AMP 579, in Healthy Male Volunteers

Journal of clinical pharmacology, 1999-10, Vol.39 (10), p.1044-1052

1999

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Pharmacokinetics and Safety of Single Intravenous Infusions of the Adenosine Agonist, AMP 579, in Patients with End-Stage Renal Insufficiency

Journal of clinical pharmacology, 2000-07, Vol.40 (7), p.745-751

2000

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The negligible systemic availability of retinoids with multiple and excessive topical application of isotretinoin 0.05% gel (Isotrex) in patients with acne vulgaris

Journal of the American Academy of Dermatology, 1991-03, Vol.24 (3), p.425-428

1991

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The pharmacokinetics and pharmacodynamics of desmopressin: effect on plasma factor VIII:C and von Willebrand factor

American journal of therapeutics, 1997-01, Vol.4 (1), p.3-8

1997

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Food Increases the Bioavailability of Acitretin

Journal of clinical pharmacology, 1988-11, Vol.28 (11), p.1051-1055

1988

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Pharmacokinetics of Otamixaban, a Direct Factor Xa Inhibitor, in Healthy Male Subjects: Pharmacokinetic Model Development for Phase 2/3 Simulation of Exposure

Pharmacokinetics and Concentration-Effect Analysis of Intravenous RGD891, a Platelet GPIIb/IIIa Antagonist, Using Mixed-Effects Modeling (NONMEM)

Pharmacokinetic/Pharmacodynamic Relationships for Otamixaban, a Direct Factor Xa Inhibitor, in Healthy Subjects

The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: A case study with fexofenadine hydrochloride

Pharmacokinetics, pharmacodynamics, and safety of a lipid-lowering adenosine A1 agonist, RPR749, in healthy subjects

Effect of Food on Pharmacokinetics of an Inhaled Drug: A Case Study with a VLA-4 Antagonist, HMR1031

A Mass Balance Study to Evaluate the Biotransformation and Excretion of [14C]-Triamcinolone Acetonide following Oral Administration

Estimating Mass Balance for Inhaled Drugs in Humans: An Example with a VLA-4 Antagonist, IVL745

Pharmacokinetic-Pharmacodynamic Modeling of the Antilipolytic Effects of an Adenosine Receptor Agonist in Healthy Volunteers

Pharmacokinetics of M100240 and MDL 100,173, a Dual Angiotensin-Converting Enzyme/Neutral Endopeptidase Inhibitor, in Healthy Young and Elderly Volunteers

Pharmacoscintigraphic comparison of HMR 1031, a VLA-4 antagonist, in healthy volunteers following delivery via a nebulizer and a dry powder inhaler

Mass balance study of [14C]M100240, a dual angiotensin-converting enzyme/neutral endopeptidase inhibitor, in healthy male subjects

Pharmacokinetics, Pharmacodynamics, and Safety of a Platelet GPIIb/IIIa Antagonist, RGD891, following Intravenous Administration in Healthy Male Volunteers

Pharmacokinetics, Safety, and Tolerability of Single Intravenous Infusions of an Adenosine Agonist, AMP 579, in Healthy Male Volunteers

Pharmacokinetics and Safety of Single Intravenous Infusions of the Adenosine Agonist, AMP 579, in Patients with End-Stage Renal Insufficiency

Population pharmacokinetics/pharmacodynamics of ciclesonide

First report of an intravenous and oral glycoprotein IIb/IIIa inhibitor (RPR 109891) in patients with recent acute coronary syndromes: Results of the TIMI 15A and 15B trials

Negligible Systemic Absorption of Topical Isotretinoin Cream: Implications for Teratogenicity

THE PHARMACOKINETICS AND PHARMACODYNAMICS OF DESMOPRESSIN: EFFECT ON PLASMA FACTOR VIII

Effects of food on the pharmacokinetics of sparfloxacin

Pharmacokinetics, Safety, and Tolerability of Single Intravenous Infusions of an Adenosine Agonist, AMP 579, in Healthy Male Volunteers

Pharmacokinetics and Safety of Single Intravenous Infusions of the Adenosine Agonist, AMP 579, in Patients with End-Stage Renal Insufficiency

The negligible systemic availability of retinoids with multiple and excessive topical application of isotretinoin 0.05% gel (Isotrex) in patients with acne vulgaris

The pharmacokinetics and pharmacodynamics of desmopressin: effect on plasma factor VIII:C and von Willebrand factor

Food Increases the Bioavailability of Acitretin

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