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PfEMP1 - A Parasite Protein Family of Key Importance in Plasmodium falciparum Malaria Immunity and Pathogenesis

Advances in parasitology, 2015-04, Vol.88, p.51-84

2015

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A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

Cell reports (Cambridge), 2018-03, Vol.22 (11), p.2951-2963

2018

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Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

The Journal of experimental medicine, 2004-11, Vol.200 (9), p.1197-1203

2004

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Differential Expression of var Gene Groups Is Associated with Morbidity Caused by Plasmodium falciparum Infection in Tanzanian Children

Infection and Immunity, 2006-07, Vol.74 (7), p.3904-3911

2006

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Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1

PLoS pathogens, 2010-09, Vol.6 (9), p.e1001083-e1001083

2010

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Hierarchical, Domain Type-Specific Acquisition of Antibodies to Plasmodium falciparum Erythrocyte Membrane Protein 1 in Tanzanian Children

Infection and Immunity, 2010-11, Vol.78 (11), p.4653-4659

2010

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Baculovirus-Expressed Constructs Induce Immunoglobulin G That Recognizes VAR2CSA on Plasmodium falciparum- Infected Erythrocytes

Infection and Immunity, 2006-07, Vol.74 (7), p.4357-4360

2006

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Spleen-dependent regulation of antigenic variation in malaria parasites: Plasmodium knowlesi SICAvar expression profiles in splenic and asplenic hosts

PloS one, 2013-10, Vol.8 (10), p.e78014-e78014

2013

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Knockdown of the Plasmodium falciparum SURFIN4.1 antigen leads to an increase of its cognate transcript

PloS one, 2017-08, Vol.12 (8), p.e0183129-e0183129

2017

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Dynamics in the cytoadherence phenotypes of Plasmodium falciparum infected erythrocytes isolated during pregnancy

PloS one, 2014-06, Vol.9 (6), p.e98577-e98577

2014

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Immunoglobulin G Antibody Reactivity to a Group A Plasmodium falciparum Erythrocyte Membrane Protein 1 and Protection from P. falciparum Malaria

Infection and Immunity, 2007-05, Vol.75 (5), p.2415-2420

2007

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Limited Cross-Reactivity among Domains of the Plasmodium falciparum Clone 3D7 Erythrocyte Membrane Protein 1 Family

Infection and Immunity, 2006-12, Vol.74 (12), p.6778-6784

2006

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Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood-brain barrier in cerebral malaria

The Journal of experimental medicine, 2021-03, Vol.218 (3)

2021

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Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria

Cell host & microbe, 2017-03, Vol.21 (3), p.403-414

2017

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Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1

The Journal of infectious diseases, 2017-06, Vol.215 (12), p.1918-1925

2017

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Gα s -coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells

The Journal of experimental medicine, 2019-03, Vol.216 (3), p.517-526

2019

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A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies

The Journal of immunology (1950), 2013-01, Vol.190 (1), p.240-249

2013

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A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

Cell reports (Cambridge), 2018-03, Vol.22 (11), p.2951-2963

2018

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Activated integrins identify functional antigen-specific CD8⁺ T cells within minutes after antigen stimulation

Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (24), p.E5536-E5545

2018

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Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

Nature (London), 2014-09, Vol.513 (7518), p.431-435

2014

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Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigen Family Varies between Groups A, B, and C

Infection and immunity, 2019-10, Vol.87 (10)

2019

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Natural and Vaccine-Induced Acquisition of Cross-Reactive IgG-Inhibiting ICAM-1-Specific Binding of a Plasmodium falciparum PfEMP1 Subtype Associated Specifically with Cerebral Malaria

Infection and immunity, 2018-04, Vol.86 (4)

2018

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Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes

PloS one, 2018-10, Vol.13 (10), p.e0204177-e0204177

2018

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Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

Malaria journal, 2016-11, Vol.15 (1), p.575-575, Article 575

2016

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A vaccine targeted specifically to prevent cerebral malaria - is there hope?

Expert review of vaccines, 2018-07, Vol.17 (7), p.565-567

2018

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PfEMP1 - A Parasite Protein Family of Key Importance in Plasmodium falciparum Malaria Immunity and Pathogenesis

A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

Differential Expression of var Gene Groups Is Associated with Morbidity Caused by Plasmodium falciparum Infection in Tanzanian Children

Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1

Hierarchical, Domain Type-Specific Acquisition of Antibodies to Plasmodium falciparum Erythrocyte Membrane Protein 1 in Tanzanian Children

Baculovirus-Expressed Constructs Induce Immunoglobulin G That Recognizes VAR2CSA on Plasmodium falciparum- Infected Erythrocytes

Spleen-dependent regulation of antigenic variation in malaria parasites: Plasmodium knowlesi SICAvar expression profiles in splenic and asplenic hosts

Knockdown of the Plasmodium falciparum SURFIN4.1 antigen leads to an increase of its cognate transcript

Dynamics in the cytoadherence phenotypes of Plasmodium falciparum infected erythrocytes isolated during pregnancy

Immunoglobulin G Antibody Reactivity to a Group A Plasmodium falciparum Erythrocyte Membrane Protein 1 and Protection from P. falciparum Malaria

Limited Cross-Reactivity among Domains of the Plasmodium falciparum Clone 3D7 Erythrocyte Membrane Protein 1 Family

Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood-brain barrier in cerebral malaria

Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria

Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1

Gα s -coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells

A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies

A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

Activated integrins identify functional antigen-specific CD8⁺ T cells within minutes after antigen stimulation

Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigen Family Varies between Groups A, B, and C

Natural and Vaccine-Induced Acquisition of Cross-Reactive IgG-Inhibiting ICAM-1-Specific Binding of a Plasmodium falciparum PfEMP1 Subtype Associated Specifically with Cerebral Malaria

Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes

Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

A vaccine targeted specifically to prevent cerebral malaria - is there hope?

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