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AMP-activated protein kinase, super metabolic regulator

Biochemical Society transactions, 2003-02, Vol.31 (Pt 1), p.162

2003

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Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition

Bioorganic & medicinal chemistry, 2019-12, Vol.27 (24), p.115157-115157, Article 115157

2019

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Substituted 1-methyl-4-phenylpyrrolidin-2-ones – Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors

European journal of medicinal chemistry, 2020-04, Vol.191, p.112120-112120, Article 112120

2020

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Structure and function of the aromatic amino acid hydroxylases

Biochemical journal, 1995-10, Vol.311 ( Pt 2) (2), p.353-366

1995

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Water wave propagation in unbounded domains. Part I: Nonreflecting boundaries

Journal of computational physics, 2014-11, Vol.276, p.729-739

2014

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Water wave propagation in unbounded domains. Part II: Numerical methods for fractional PDEs

Journal of computational physics, 2014-10, Vol.275, p.443-458

2014

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Delineation of the catalytic core of phenylalanine hydroxylase and identification of glutamate 286 as a critical residue for pterin function

The Journal of biological chemistry, 1994-08, Vol.269 (32), p.20369-20375

1994

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Structural basis of autoregulation of phenylalanine hydroxylase

Nature structural biology, 1999-05, Vol.6 (5), p.442-448

1999

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Biophysical Characterization of Interactions Involving Importin-α during Nuclear Import

The Journal of biological chemistry, 2001-09, Vol.276 (36), p.34189-34198

2001

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Localization of Cofactor Binding Sites with Monoclonal Anti-Idiotype Antibodies: Phenylalanine Hydroxylase

Proceedings of the National Academy of Sciences - PNAS, 1991-07, Vol.88 (13), p.5734-5738

1991

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Essential role of the N-terminal autoregulatory sequence in the regulation of phenylalanine hydroxylase

FEBS letters, 2001-01, Vol.488 (3), p.196-200

2001

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Regulation and crystallization of phosphorylated and dephosphorylated forms of truncated dimeric phenylalanine hydroxylase

Protein science, 1997-06, Vol.6 (6), p.1352-1357

1997

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Turn up the HEAT

Structure, 1999-05, Vol.7 (5), p.R91-R97

1999

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Identification of serotonergic neurons in human brain by a monoclonal antibody binding to all three aromatic amino acid hydroxylases

Brain research, 1987-11, Vol.426 (1), p.19-27

1987

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Structural interpretation of mutations in phenylalanine hydroxylase protein aids in identifying genotype-phenotype correlations in phenylketonuria

European journal of human genetics : EJHG, 2000-09, Vol.8 (9), p.683-696

2000

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Functional analysis of the effect of monoclonal antibodies on monkey liver phenylalanine hydroxylase

Biochemical journal, 1986-04, Vol.235 (1), p.133-138

1986

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Functional Analysis, Using in Vitro Mutagenesis, of Amino Acids Located in the Phenylalanine Hydroxylase Active Site

Archives of biochemistry and biophysics, 2000-12, Vol.384 (2), p.238-244

2000

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AMPK β Subunit Targets Metabolic Stress Sensing to Glycogen

Current biology, 2003-05, Vol.13 (10), p.867-871

2003

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Structure function studies of the phenylalanine hydroxylase active site and a summary of structural features

Advances in experimental medicine and biology, 1993, Vol.338, p.55

1993

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Src Kinase Activates Endothelial Nitric-oxide Synthase by Phosphorylating Tyr-83

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.35943-35952

2005

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Anti-idiotypic antibodies elicited by pterin recognize active site epitopes in dihydrofolate reductases and dihydropteridine reductase

Archives of biochemistry and biophysics, 1989-12, Vol.275 (2), p.344-353

1989

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Interaction with a monoclonal antibody alters the expression of co-operativity by phenylalanine hydroxylase from rat liver

Biochemical journal, 1989-01, Vol.257 (2), p.383-388

1989

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Isolation and characterization of a myeloma--spleen-cell hybrid producing antibody to phenylalanine hydroxylase

Biochemical journal, 1980-12, Vol.191 (3), p.777-783

1980

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Structure/function analysis of the domains required for the multimerisation of phenylalanine hydroxylase

Biochimica et biophysica acta, 1998-02, Vol.1382 (2), p.295-304

1998

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Erectile Dysfunction Predicts Cardiovascular Events in High-Risk Patients Receiving Telmisartan, Ramipril, or Both: The ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (ONTARGET/ TRANSCEND) Trials

Circulation (New York, N.Y.), 2010-03, Vol.121 (12), p.1439-1446

2010

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AMP-activated protein kinase, super metabolic regulator

Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition

Substituted 1-methyl-4-phenylpyrrolidin-2-ones – Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors

Structure and function of the aromatic amino acid hydroxylases

Water wave propagation in unbounded domains. Part I: Nonreflecting boundaries

Water wave propagation in unbounded domains. Part II: Numerical methods for fractional PDEs

Delineation of the catalytic core of phenylalanine hydroxylase and identification of glutamate 286 as a critical residue for pterin function

Structural basis of autoregulation of phenylalanine hydroxylase

Biophysical Characterization of Interactions Involving Importin-α during Nuclear Import

Localization of Cofactor Binding Sites with Monoclonal Anti-Idiotype Antibodies: Phenylalanine Hydroxylase

Essential role of the N-terminal autoregulatory sequence in the regulation of phenylalanine hydroxylase

Regulation and crystallization of phosphorylated and dephosphorylated forms of truncated dimeric phenylalanine hydroxylase

Turn up the HEAT

Identification of serotonergic neurons in human brain by a monoclonal antibody binding to all three aromatic amino acid hydroxylases

Structural interpretation of mutations in phenylalanine hydroxylase protein aids in identifying genotype-phenotype correlations in phenylketonuria

Functional analysis of the effect of monoclonal antibodies on monkey liver phenylalanine hydroxylase

Functional Analysis, Using in Vitro Mutagenesis, of Amino Acids Located in the Phenylalanine Hydroxylase Active Site

AMPK β Subunit Targets Metabolic Stress Sensing to Glycogen

Structure function studies of the phenylalanine hydroxylase active site and a summary of structural features

Src Kinase Activates Endothelial Nitric-oxide Synthase by Phosphorylating Tyr-83

Anti-idiotypic antibodies elicited by pterin recognize active site epitopes in dihydrofolate reductases and dihydropteridine reductase

Interaction with a monoclonal antibody alters the expression of co-operativity by phenylalanine hydroxylase from rat liver

Isolation and characterization of a myeloma--spleen-cell hybrid producing antibody to phenylalanine hydroxylase

Structure/function analysis of the domains required for the multimerisation of phenylalanine hydroxylase

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