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Finding the Keys to the CAR: Identifying Novel Target Antigens for T Cell Redirection Immunotherapies

International journal of molecular sciences, 2020-01, Vol.21 (2), p.515

2020

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Cellular and Molecular Mechanisms of CD8 + T Cell Differentiation, Dysfunction and Exhaustion

International journal of molecular sciences, 2020-10, Vol.21 (19), p.7357

2020

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Indigenous Australian genomes show deep structure and rich novel variation

Nature (London), 2023-12, Vol.624 (7992), p.593-3

2023

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Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time

The Journal of experimental medicine, 2015-03, Vol.212 (3), p.307-317

2015

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Identification and Targeting of Mutant Peptide Neoantigens in Cancer Immunotherapy

Cancers, 2021-08, Vol.13 (16), p.4245

2021

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Synthetic biology, genetic circuits and machine learning: a new age of cancer therapy

Molecular oncology, 2023-06, Vol.17 (6), p.946-949

2023

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Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

Blood, 2013-04, Vol.121 (14), p.2659-2668

2013

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The Evolving Protein Engineering in the Design of Chimeric Antigen Receptor T Cells

International journal of molecular sciences, 2019-12, Vol.21 (1), p.204

2019

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Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma

Scientific reports, 2018-03, Vol.8 (1), p.4159-14, Article 4159

2018

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De novo-designed transmembrane domains tune engineered receptor functions

eLife, 2022-05, Vol.11

2022

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To go or not to go? Biological logic gating engineered T cells

Journal for immunotherapy of cancer, 2022-04, Vol.10 (4), p.e004185

2022

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The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells

Haematologica (Roma), 2023-01, Vol.108 (1), p.83

2023

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Centrosome docking at the immunological synapse is controlled by Lck signaling

The Journal of cell biology, 2011-02, Vol.192 (4), p.663-674

2011

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From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress

Signal transduction and targeted therapy, 2023-10, Vol.8 (1), p.400-400, Article 400

2023

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A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma

Frontiers in oncology, 2023-08, Vol.13, p.1192448-1192448

2023

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CAR T-Cell Therapy for Glioblastoma

The New England journal of medicine, 2024-04, Vol.390 (14), p.1329

2024

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Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma

Clinical & translational immunology, 2021, Vol.10 (5), p.e1283-n/a

2021

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Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL

eLife, 2014-03, Vol.3, p.e01310

2014

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Human EGFRvIII chimeric antigen receptor T cells demonstrate favorable safety profile and curative responses in orthotopic glioblastoma

Clinical & translational immunology, 2023-01, Vol.12 (3), p.e1440-e1440

2023

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Human γδ T‐cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation

Clinical & translational immunology, 2019, Vol.8 (9), p.e1079-n/a

2019

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Location rather than CD62L phenotype is critical in the early establishment of influenza-specific CD8⁺ T cell memory

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (23), p.9782-9787

2007

Volltextzugriff (PDF)

The Strength of T Cell Receptor Signal Controls the Polarization of Cytotoxic Machinery to the Immunological Synapse

Immunity (Cambridge, Mass.), 2009-10, Vol.31 (4), p.621-631

2009

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Flow Cytometry Identification of Cell Compartments in the Murine Brain

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2691, p.185

2023

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BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Cell death and differentiation, 2022-07, Vol.29 (7), p.1335-1348

2022

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Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma

Clinical & translational immunology, 2021, Vol.10 (7), p.n/a

2021

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Finding the Keys to the CAR: Identifying Novel Target Antigens for T Cell Redirection Immunotherapies

Cellular and Molecular Mechanisms of CD8 + T Cell Differentiation, Dysfunction and Exhaustion

Indigenous Australian genomes show deep structure and rich novel variation

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time

Identification and Targeting of Mutant Peptide Neoantigens in Cancer Immunotherapy

Synthetic biology, genetic circuits and machine learning: a new age of cancer therapy

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

The Evolving Protein Engineering in the Design of Chimeric Antigen Receptor T Cells

Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma

De novo-designed transmembrane domains tune engineered receptor functions

To go or not to go? Biological logic gating engineered T cells

The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells

Centrosome docking at the immunological synapse is controlled by Lck signaling

From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress

A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma

CAR T-Cell Therapy for Glioblastoma

Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma

Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL

Human EGFRvIII chimeric antigen receptor T cells demonstrate favorable safety profile and curative responses in orthotopic glioblastoma

Human γδ T‐cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation

Location rather than CD62L phenotype is critical in the early establishment of influenza-specific CD8⁺ T cell memory

The Strength of T Cell Receptor Signal Controls the Polarization of Cytotoxic Machinery to the Immunological Synapse

Flow Cytometry Identification of Cell Compartments in the Murine Brain

BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma

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