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Mechanisms of triazole resistance in Aspergillus fumigatus

Environmental microbiology, 2020-12, Vol.22 (12), p.4934-4952

2020

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Emerging threat of triazole-resistant Aspergillus fumigatus

Journal of antimicrobial chemotherapy, 2019-04, Vol.74 (4), p.835-842

2019

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The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species

Nature communications, 2024-05, Vol.15 (1), p.4261-4261, Article 4261

2024

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A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1

Nature communications, 2024-04, Vol.15 (1), p.3642-3642, Article 3642

2024

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Delineation of the Direct Contribution of Candida auris ERG11 Mutations to Clinical Triazole Resistance

Microbiology spectrum, 2021-12, Vol.9 (3), p.e0158521

2021

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Characterization of the Efflux Capability and Substrate Specificity of Aspergillus fumigatus PDR5-like ABC Transporters Expressed in Saccharomyces cerevisiae

mBio, 2020-03, Vol.11 (2)

2020

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Current and prospective treatments for multidrug-resistant gram-positive infections

Expert opinion on pharmacotherapy, 2013-10, Vol.14 (14), p.1919-1932

2013

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The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase

mBio, 2024-05, Vol.15 (5), p.e0063324

2024

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The β-Lactams Strike Back: Ceftazidime-Avibactam

Pharmacotherapy, 2015-08, Vol.35 (8), p.755-770

2015

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The [beta]-Lactams Strike Back: Ceftazidime-Avibactam

Pharmacotherapy, 2015-08, Vol.35 (8), p.755

2015

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hapE and hmg1 Mutations Are Drivers of cyp51A -Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate

Microbiology spectrum, 2023-06, Vol.11 (3), p.e0518822-e0518822

2023

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Rapid Hypothesis Testing in Candida albicans Clinical Isolates Using a Cloning-Free, Modular, and Recyclable System for CRISPR-Cas9 Mediated Mutant and Revertant Construction

Microbiology spectrum, 2022-06, Vol.10 (3), p.e0263021-e0263021

2022

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Azole Antifungal Resistance in Candida albicans and Emerging Non- albicans Candida Species

Frontiers in microbiology, 2017-01, Vol.7, p.2173-2173

2017

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Imipenem‐Cilastatin‐Relebactam: A Novel β‐Lactam–β‐Lactamase Inhibitor Combination for the Treatment of Multidrug‐Resistant Gram‐Negative Infections

Pharmacotherapy, 2020-04, Vol.40 (4), p.343-356

2020

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The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris

Current opinion in microbiology, 2022-12, Vol.70, p.102208-102208, Article 102208

2022

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Abrogation of Triazole Resistance upon Deletion of CDR1 in a Clinical Isolate of Candida auris

Antimicrobial agents and chemotherapy, 2019-04, Vol.63 (4)

2019

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Mutations in hmg1 , Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

mBio, 2019-04, Vol.10 (2)

2019

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Mutations in TAC1 and ERG11 are major drivers of triazole antifungal resistance in clinical isolates of Candida parapsilosis

Clinical microbiology and infection, 2023-12, Vol.29 (12), p.1602.e1-1602.e7

2023

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Mutations in TAC1B : a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

mBio, 2020-05, Vol.11 (3)

2020

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In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris

Clinical microbiology and infection, 2022-06, Vol.28 (6), p.838-843

2022

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Candida parapsilosis Mdr1B and Cdr1B Are Drivers of Mrr1-Mediated Clinical Fluconazole Resistance

Antimicrobial agents and chemotherapy, 2022-07, Vol.66 (7), p.e0028922-e0028922

2022

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Analysis of clinical Candida parapsilosis isolates reveals copy number variation in key fluconazole resistance genes

Antimicrobial agents and chemotherapy, 2024-05

2024

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Oritavancin: A New Lipoglycopeptide Antibiotic in the Treatment of Gram-Positive Infections

Infectious diseases and therapy, 2016-03, Vol.5 (1), p.1-15

2016

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Tedizolid Phosphate: a Next-Generation Oxazolidinone

Infectious diseases and therapy, 2015-03, Vol.4 (1), p.1-14

2015

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Isavuconazole: Pharmacology, Pharmacodynamics, and Current Clinical Experience with a New Triazole Antifungal Agent

Pharmacotherapy, 2015-11, Vol.35 (11), p.1037-1051

2015

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Mechanisms of triazole resistance in Aspergillus fumigatus

Emerging threat of triazole-resistant Aspergillus fumigatus

The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species

A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1

Delineation of the Direct Contribution of Candida auris ERG11 Mutations to Clinical Triazole Resistance

Characterization of the Efflux Capability and Substrate Specificity of Aspergillus fumigatus PDR5-like ABC Transporters Expressed in Saccharomyces cerevisiae

Current and prospective treatments for multidrug-resistant gram-positive infections

The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase

The β-Lactams Strike Back: Ceftazidime-Avibactam

The [beta]-Lactams Strike Back: Ceftazidime-Avibactam

hapE and hmg1 Mutations Are Drivers of cyp51A -Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate

Rapid Hypothesis Testing in Candida albicans Clinical Isolates Using a Cloning-Free, Modular, and Recyclable System for CRISPR-Cas9 Mediated Mutant and Revertant Construction

Azole Antifungal Resistance in Candida albicans and Emerging Non- albicans Candida Species

Imipenem‐Cilastatin‐Relebactam: A Novel β‐Lactam–β‐Lactamase Inhibitor Combination for the Treatment of Multidrug‐Resistant Gram‐Negative Infections

The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris

Abrogation of Triazole Resistance upon Deletion of CDR1 in a Clinical Isolate of Candida auris

Mutations in hmg1 , Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

Mutations in TAC1 and ERG11 are major drivers of triazole antifungal resistance in clinical isolates of Candida parapsilosis

Mutations in TAC1B : a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris

Candida parapsilosis Mdr1B and Cdr1B Are Drivers of Mrr1-Mediated Clinical Fluconazole Resistance

Analysis of clinical Candida parapsilosis isolates reveals copy number variation in key fluconazole resistance genes

Oritavancin: A New Lipoglycopeptide Antibiotic in the Treatment of Gram-Positive Infections

Tedizolid Phosphate: a Next-Generation Oxazolidinone

Isavuconazole: Pharmacology, Pharmacodynamics, and Current Clinical Experience with a New Triazole Antifungal Agent

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