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Regulating IRFs in IFN Driven Disease

Frontiers in immunology, 2019-03, Vol.10, p.325-325

Jefferies, Caroline A

2019

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Nucleic Acid Sensors as Therapeutic Targets for Human Disease

Immunity (Cambridge, Mass.), 2020-07, Vol.53 (1), p.78-97

2020

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TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms

PloS one, 2014-08, Vol.9 (8), p.e103609-e103609

2014

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Btk regulates macrophage polarization in response to lipopolysaccharide

PloS one, 2014-01, Vol.9 (1), p.e85834

2014

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Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon

American journal of physiology: Gastrointestinal and liver physiology, 2017-06, Vol.312 (6), p.G550-G558

2017

Volltextzugriff (PDF)

Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors

PloS one, 2010-07, Vol.5 (7), p.e11776-e11776

2010

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IRF5-mediated signaling and implications for SLE

Clinical immunology (Orlando, Fla.), 2014-08, Vol.153 (2), p.343-352

2014

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Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

The Journal of experimental medicine, 2009-08, Vol.206 (8), p.1661-1671

2009

Volltextzugriff (PDF)

Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity

PloS one, 2012-03, Vol.7 (3), p.e34041-e34041

2012

Volltextzugriff (PDF)

Herpes simplex virus 1 targets IRF7 via ICP0 to limit type I IFN induction

Scientific reports, 2020-12, Vol.10 (1), p.22216-22216, Article 22216

2020

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Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

Frontiers in immunology, 2020-09, Vol.11, p.554725

2020

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The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3

The Journal of immunology (1950), 2008-08, Vol.181 (3), p.1780-1786

2008

Volltextzugriff (PDF)

MicroRNA-302d targets IRF9 to regulate the IFN-induced gene expression in SLE

Journal of autoimmunity, 2017-05, Vol.79, p.105-111

2017

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TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (33), p.16479-16488

2019

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α‐Ketoglutarate–Dependent KDM6 Histone Demethylases and Interferon‐Stimulated Gene Expression in Lupus

Arthritis & rheumatology (Hoboken, N.J.), 2024-03, Vol.76 (3), p.396-410

2024

Volltextzugriff (PDF)

High-throughput mRNA-seq atlas of human placenta shows vast transcriptome remodeling from first to third trimester

Biology of reproduction, 2024-05, Vol.110 (5), p.936

2024

Volltextzugriff (PDF)

Neutrophils Contribute to ER Stress in Lung Epithelial Cells in the Pristane-Induced Diffuse Alveolar Hemorrhage Mouse Model

Frontiers in immunology, 2022-02, Vol.13, p.790043-790043

2022

Volltextzugriff (PDF)

miR-744-5p contributes to ocular inflammation in patients with primary Sjogrens Syndrome

Scientific reports, 2020-05, Vol.10 (1), p.7484-7484, Article 7484

2020

Volltextzugriff (PDF)

Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization

Immunity (Cambridge, Mass.), 2013-01, Vol.38 (1), p.66-78

2013

Volltextzugriff (PDF)

IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation

JCI insight, 2018-08, Vol.3 (15)

2018

Volltextzugriff (PDF)

MyD88 Adapter-like (Mal) Is Phosphorylated by Bruton's Tyrosine Kinase during TLR2 and TLR4 Signal Transduction

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.10489-10495

2006

Volltextzugriff (PDF)

Type 1 Interferon Gene Signature Promotes RBC Alloimmunization in a Lupus Mouse Model

Frontiers in immunology, 2020-09, Vol.11, p.584254

2020

Volltextzugriff (PDF)

High-throughput mRNA sequencing of human placenta shows sex differences across gestation

Placenta (Eastbourne), 2024-05, Vol.150, p.8-21

2024

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TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems

PloS one, 2014-07, Vol.9 (7), p.e101503-e101503

2014

Volltextzugriff (PDF)

Macrophage MMP10 Regulates TLR7-Mediated Tolerance

Frontiers in immunology, 2018-12, Vol.9, p.2817-2817

2018

Volltextzugriff (PDF)

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Regulating IRFs in IFN Driven Disease

Nucleic Acid Sensors as Therapeutic Targets for Human Disease

TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms

Btk regulates macrophage polarization in response to lipopolysaccharide

Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon

Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors

IRF5-mediated signaling and implications for SLE

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity

Herpes simplex virus 1 targets IRF7 via ICP0 to limit type I IFN induction

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3

MicroRNA-302d targets IRF9 to regulate the IFN-induced gene expression in SLE

TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages

α‐Ketoglutarate–Dependent KDM6 Histone Demethylases and Interferon‐Stimulated Gene Expression in Lupus

High-throughput mRNA-seq atlas of human placenta shows vast transcriptome remodeling from first to third trimester

Neutrophils Contribute to ER Stress in Lung Epithelial Cells in the Pristane-Induced Diffuse Alveolar Hemorrhage Mouse Model

miR-744-5p contributes to ocular inflammation in patients with primary Sjogrens Syndrome

Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization

IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation

MyD88 Adapter-like (Mal) Is Phosphorylated by Bruton's Tyrosine Kinase during TLR2 and TLR4 Signal Transduction

Type 1 Interferon Gene Signature Promotes RBC Alloimmunization in a Lupus Mouse Model

High-throughput mRNA sequencing of human placenta shows sex differences across gestation

TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems

Macrophage MMP10 Regulates TLR7-Mediated Tolerance

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