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Pathogenesis of myeloproliferative neoplasms

Experimental hematology, 2015-08, Vol.43 (8), p.599-608

2015

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ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (15), p.4642-4647

2015

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Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN

Blood, 2015-03, Vol.125 (13), p.2131-2140

2015

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Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines

Endocrine-related cancer, 2009-06, Vol.16 (2), p.429-441

2009

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Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

Haematologica (Roma), 2014-04, Vol.99 (4), p.e52-e54

2014

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Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes

American journal of physiology: endocrinology and metabolism, 2013-01, Vol.304 (1), p.E1-E13

2013

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Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2-V617F–driven mouse model of MPNs

Blood, 2014-06, Vol.123 (25), p.3943-3950

2014

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Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation

Diabetology and metabolic syndrome, 2011-07, Vol.3 (1), p.16-16, Article 16

2011

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Specific involvement of glycogen synthase kinase-3 in the function and activity of sex steroid hormone receptors reveals the complexity of their regulation

The Journal of steroid biochemistry and molecular biology, 2009-11, Vol.117 (4), p.87-92

2009

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JAK2 exon 12 mutant mice display isolated erythrocytosis and changes in iron metabolism favoring increased erythropoiesis

Blood, 2016-08, Vol.128 (6), p.839-851

2016

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Glycogen Synthase Kinase-3 Interacts with and Phosphorylates Estrogen Receptor α and Is Involved in the Regulation of Receptor Activity

The Journal of biological chemistry, 2005-09, Vol.280 (38), p.33006-33014

2005

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Glycogen Synthase Kinase-3 Protects Estrogen Receptor α from Proteasomal Degradation and Is Required for Full Transcriptional Activity of the Receptor

Molecular endocrinology (Baltimore, Md.), 2007-10, Vol.21 (10), p.2427-2439

2007

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Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model

Blood, 2013-02, Vol.121 (7), p.1188-1199

2013

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Mechanisms of metformin action on glucose transport and metabolism in human adipocytes

Biochemical pharmacology, 2010-12, Vol.80 (11), p.1736-1745

2010

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Complex subclone structure that responds differentially to therapy in a patient with essential thrombocythemia and chronic myeloid leukemia

Blood, 2013-11, Vol.122 (22), p.3694-3696

2013

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JAK2V617F and Loss of Ezh2 in Hematopoietic Cells Contribute Synergistically to Myeloproliferative Neoplasm Initiation Potential, and Accelerate Progression of Disease

Blood, 2014-12, Vol.124 (21), p.158-158

2014

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Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharide-induced lipolysis in human adipocytes

Innate immunity (London, England), 2012-02, Vol.18 (1), p.25-34

2012

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Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes

The journal of clinical endocrinology and metabolism, 2011-02, Vol.96 (2), p.E297-E303

2011

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Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes

American journal of physiology: endocrinology and metabolism, 2013, Vol.67 (1)

2013

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Role of calcium in lipopolysaccharide-induced calcitonin gene expression in human adipocytes

Innate immunity (London, England), 2011-08, Vol.17 (4), p.403-413

2011

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Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes

Molecular endocrinology (Baltimore, Md.), 2011-01, Vol.25 (1), p.195-196

2011

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Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and cell proliferation

Diabetology and metabolic syndrome, 2011-07, Vol.3, p.16

2011

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Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and -induced lipolysis in human adipocytes

Archives of physiology and biochemistry, 2011-10, Vol.117 (4), p.209-214

2011

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Glycogen Synthase Kinase-3 Interacts with and Phosphorylates Estrogen Receptor Î± and Is Involved in the Regulation of Receptor Activity

The Journal of biological chemistry, 2005-09, Vol.280 (38), p.33006

2005

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P42. Glycogen synthase kinase 3beta (GSK3beta) as a key component of estradiol signalling pathway

European journal of cancer supplements, 2006-06, Vol.4 (6), p.42-42

2006

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Pathogenesis of myeloproliferative neoplasms

ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation

Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN

Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines

Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes

Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2-V617F–driven mouse model of MPNs

Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation

Specific involvement of glycogen synthase kinase-3 in the function and activity of sex steroid hormone receptors reveals the complexity of their regulation

JAK2 exon 12 mutant mice display isolated erythrocytosis and changes in iron metabolism favoring increased erythropoiesis

Glycogen Synthase Kinase-3 Interacts with and Phosphorylates Estrogen Receptor α and Is Involved in the Regulation of Receptor Activity

Glycogen Synthase Kinase-3 Protects Estrogen Receptor α from Proteasomal Degradation and Is Required for Full Transcriptional Activity of the Receptor

Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model

Mechanisms of metformin action on glucose transport and metabolism in human adipocytes

Complex subclone structure that responds differentially to therapy in a patient with essential thrombocythemia and chronic myeloid leukemia

JAK2V617F and Loss of Ezh2 in Hematopoietic Cells Contribute Synergistically to Myeloproliferative Neoplasm Initiation Potential, and Accelerate Progression of Disease

Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharide-induced lipolysis in human adipocytes

Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes

Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes

Role of calcium in lipopolysaccharide-induced calcitonin gene expression in human adipocytes

Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes

Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and cell proliferation

Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and -induced lipolysis in human adipocytes

Glycogen Synthase Kinase-3 Interacts with and Phosphorylates Estrogen Receptor Î± and Is Involved in the Regulation of Receptor Activity

P42. Glycogen synthase kinase 3beta (GSK3beta) as a key component of estradiol signalling pathway

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