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Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells

The Journal of nutrition, 2017-04, Vol.147 (4), p.482-498

2017

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Incrimination of Heterogeneous Nuclear Ribonucleoprotein E1 (hnRNP-E1) as a Candidate Sensor of Physiological Folate Deficiency

The Journal of biological chemistry, 2011-11, Vol.286 (45), p.39100-39115

2011

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Effect of ethanol on hydrogen peroxide-induced AMPK phosphorylation

American journal of physiology: Gastrointestinal and liver physiology, 2008-12, Vol.295 (6), p.G1173-G1181

2008

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Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure

Bioorganic & medicinal chemistry, 2010-08, Vol.18 (16), p.5950-5964

2010

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From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: Synthesis and biological evaluation of valproic esters of 3′-C-methyladenosine

Bioorganic & medicinal chemistry letters, 2014-11, Vol.24 (22), p.5304-5309

2014

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Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: Targeting the pyrophosphate binding sub-domain

Bioorganic & medicinal chemistry, 2011-03, Vol.19 (5), p.1594-1605

2011

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Influence of Physiologic Folate Deficiency on Human Papillomavirus Type 16 (HPV16)-harboring Human Keratinocytes in Vitro and in Vivo

The Journal of biological chemistry, 2012-04, Vol.287 (15), p.12559-12577

2012

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Variability of Apoptosis and Response in N1-S1 Rodent Hepatomas to Benzamide Riboside and Correlation to Early Changes in Water Apparent Diffusion Coefficient and Sodium MR Imaging

Journal of vascular and interventional radiology, 2013-06, Vol.24 (6), p.894-900

2013

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Technical Aspects of Imaging and Transfemoral Arterial Treatment of N1-S1 Tumors in Rats: An Appropriate Model to Test the Biology and Therapeutic Response to Transarterial Treatments of Liver Cancers

Journal of vascular and interventional radiology, 2009-03, Vol.20 (3), p.410-414

2009

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Ribose-Modified Purine Nucleosides as Ribonucleotide Reductase Inhibitors. Synthesis, Antitumor Activity, and Molecular Modeling of N 6-Substituted 3′-C-Methyladenosine Derivatives

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4260-4269

2008

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Predicting Response to Benzamide Riboside Chemotherapy in Hepatocellular Carcinoma Using Apparent Diffusion Coefficient of Water

Anticancer research, 2011-06, Vol.31 (6), p.2045-2051

2011

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Can targeting organic anion transporter polypeptide (OATP) genes play a key role in drug therapy

Cancer biology & therapy, 2008-09, Vol.7 (9), p.1456-1459

2008

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Effects of WY-14,643 on the phosphorylation and activation of AMP-dependent protein kinase

Archives of biochemistry and biophysics, 2009-05, Vol.485 (1), p.10-15

2009

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Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas

Biochemical journal, 2004-01, Vol.377 (Pt 2), p.317-326

2004

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Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5'-mononucleotide adenylyltransferase-2

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2011-11, Vol.7 (6), p.718

2011

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Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents

European journal of medicinal chemistry, 2011-05, Vol.46 (5), p.1499-1504

2011

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Mycophenolic acid analogs with a modified metabolic profile

Bioorganic & medicinal chemistry, 2008-10, Vol.16 (20), p.9340-9345

2008

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Probing Binding Requirements of Type I and Type II Isoforms of Inosine Monophosphate Dehydrogenase with Adenine-Modified Nicotinamide Adenine Dinucleotide Analogues

Journal of medicinal chemistry, 2007-11, Vol.50 (23), p.5743-5751

2007

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Antitumor Activity of C-Methyl-β-d-ribofuranosyladenine Nucleoside Ribonucleotide Reductase Inhibitors

Journal of medicinal chemistry, 2005-07, Vol.48 (15), p.4983-4989

2005

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Studies on the mechanism of action of benzamide riboside: a novel inhibitor of IMP dehydrogenase

Current medicinal chemistry, 2002-04, Vol.9 (7), p.743

2002

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Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3152-3155

2007

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Ribose-Modified Purine Nucleosides as Ribonucleotide Reductase Inhibitors. Synthesis, Antitumor Activity, and Molecular Modeling of N6-Substituted 3′-C-Methyladenosine Derivatives

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4260-4269

2008

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Maternal folate deficiency results in selective upregulation of folate receptors and heterogeneous nuclear ribonucleoprotein-E1 associated with multiple subtle aberrations in fetal tissues

Birth defects research. A Clinical and molecular teratology, 2005-01, Vol.73 (1), p.6-28

2005

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Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase

Current medicinal chemistry, 2002-04, Vol.9 (7), p.749

2002

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Pteroyl-γ-glutamate-cysteine synthesis and its application in folate receptor-mediated cancer cell targeting using folate-tethered liposomes

Analytical biochemistry, 2004-09, Vol.332 (1), p.168-177

2004

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Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells

Incrimination of Heterogeneous Nuclear Ribonucleoprotein E1 (hnRNP-E1) as a Candidate Sensor of Physiological Folate Deficiency

Effect of ethanol on hydrogen peroxide-induced AMPK phosphorylation

Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure

From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: Synthesis and biological evaluation of valproic esters of 3′-C-methyladenosine

Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: Targeting the pyrophosphate binding sub-domain

Influence of Physiologic Folate Deficiency on Human Papillomavirus Type 16 (HPV16)-harboring Human Keratinocytes in Vitro and in Vivo

Variability of Apoptosis and Response in N1-S1 Rodent Hepatomas to Benzamide Riboside and Correlation to Early Changes in Water Apparent Diffusion Coefficient and Sodium MR Imaging

Technical Aspects of Imaging and Transfemoral Arterial Treatment of N1-S1 Tumors in Rats: An Appropriate Model to Test the Biology and Therapeutic Response to Transarterial Treatments of Liver Cancers

Ribose-Modified Purine Nucleosides as Ribonucleotide Reductase Inhibitors. Synthesis, Antitumor Activity, and Molecular Modeling of N 6-Substituted 3′-C-Methyladenosine Derivatives

Predicting Response to Benzamide Riboside Chemotherapy in Hepatocellular Carcinoma Using Apparent Diffusion Coefficient of Water

Can targeting organic anion transporter polypeptide (OATP) genes play a key role in drug therapy

Effects of WY-14,643 on the phosphorylation and activation of AMP-dependent protein kinase

Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas

Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5'-mononucleotide adenylyltransferase-2

Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents

Mycophenolic acid analogs with a modified metabolic profile

Probing Binding Requirements of Type I and Type II Isoforms of Inosine Monophosphate Dehydrogenase with Adenine-Modified Nicotinamide Adenine Dinucleotide Analogues

Antitumor Activity of C-Methyl-β-d-ribofuranosyladenine Nucleoside Ribonucleotide Reductase Inhibitors

Studies on the mechanism of action of benzamide riboside: a novel inhibitor of IMP dehydrogenase

Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor

Ribose-Modified Purine Nucleosides as Ribonucleotide Reductase Inhibitors. Synthesis, Antitumor Activity, and Molecular Modeling of N6-Substituted 3′-C-Methyladenosine Derivatives

Maternal folate deficiency results in selective upregulation of folate receptors and heterogeneous nuclear ribonucleoprotein-E1 associated with multiple subtle aberrations in fetal tissues

Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase

Pteroyl-γ-glutamate-cysteine synthesis and its application in folate receptor-mediated cancer cell targeting using folate-tethered liposomes

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