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Coumarins and P450s, Studies Reported to-Date

Molecules (Basel, Switzerland), 2019-04, Vol.24 (8), p.1620

2019

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Cytochrome P450 family 1 inhibitors and structure-activity relationships

Molecules, 2013-11, Vol.18 (12), p.14470-14495

2013

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Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date

Molecules (Basel, Switzerland), 2017-07, Vol.22 (7), p.1143

2017

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Ligands of Therapeutic Utility for the Liver X Receptors

Molecules (Basel, Switzerland), 2017-01, Vol.22 (1), p.88

2017

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Small molecule tyrosine kinase inhibitors of ErbB2/HER2/Neu in the treatment of aggressive breast cancer

Molecules, 2014-09, Vol.19 (9), p.15196-15212

2014

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Inhibition of Cytochrome P450 Enzymes by Quinones and Anthraquinones

Chemical research in toxicology, 2012-02, Vol.25 (2), p.357-365

2012

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Insights on cytochrome p450 enzymes and inhibitors obtained through QSAR studies

Molecules, 2012-08, Vol.17 (8), p.9283-9305

2012

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7-Ethynylcoumarins: Selective Inhibitors of Human Cytochrome P450s 1A1 and 1A2

Chemical research in toxicology, 2012-05, Vol.25 (5), p.1047-1057

2012

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Abstract 6360: Development of a new substituted 1,3-dioxoisoindoline series that are RPS6K1 protein kinase inhibitors as potential cancer therapeutics

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6360-6360

2020

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Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme

Drug metabolism letters, 2017-01, Vol.10 (4), p.270-277

2017

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Development of Flavone Propargyl Ethers as Potent and Selective Inhibitors of Cytochrome P450 Enzymes 1A1 and 1A2

Drug metabolism letters, 2013-07, Vol.6 (4), p.275-284

2013

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Identification of New Mono/Dihydroxynaphthoquinone as Lead Agents That Inhibit the Growth of Refractive and Triple-Negative Breast Cancer Cell Lines

ACS omega, 2019-06, Vol.4 (6), p.10610-10619

2019

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Design, Synthesis, and Biological Studies of Flavone-Based Esters and Acids as Potential P450 2A6 Inhibitors

Chemical research in toxicology, 2023-12, Vol.36 (12), p.1973-1979

2023

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Synthetic Method to Form 2,2′-Bis(naphthoquinone) Compounds

Journal of organic chemistry, 2017-12, Vol.82 (24), p.13686-13692

2017

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Crystal structure of 4-bromo-5,7-dimethoxy-2,3-dihydro-1 H -inden-1-one

Acta crystallographica. Section E, Crystallographic communications, 2024-08, Vol.80 (8), p.873-877

2024

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Modification and Biological Evaluation of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6653-6667

2014

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Crystal structure of 4-bromo-5,7-dimethoxy-2,3-dihydro-1H-inden-1-one

Acta crystallographica. Section E, Crystallographic communications, 2024-08, Vol.80 (8), p.873-877

2024

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Crystal structure of 4-bromo-5,7-dimeth-oxy-2,3-di-hydro-1H-inden-1-one

Acta crystallographica. Section E, Crystallographic communications, 2024-08, Vol.80 (Pt 8), p.873-877

2024

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Pyranoflavones: A Group of Small-Molecule Probes for Exploring the Active Site Cavities of Cytochrome P450 Enzymes 1A1, 1A2, and 1B1

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.4082-4092

2013

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Identification of CYP 2A6 inhibitors in an effort to mitigate the harmful effects of the phytochemical nicotine

Journal of Cancer Metastasis and Treatment, 2021, Vol.7

2021

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Abstract B058: Drug resistant HER2Δ16 overexpression cells are sensitive to a new class of tyrosine kinase inhibitors

Molecular cancer research, 2013-10, Vol.11 (10_Supplement), p.B058-B058

2013

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Identification of quinones as novel PIM1 kinase inhibitors

Bioorganic & medicinal chemistry letters, 2016-07, Vol.26 (13), p.3187-3191

2016

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Abstract 343: New derivatives of 1,3-dioxoisoindoline: Potential breast cancer therapeutics that are S6K1 inhibitors

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.343-343

2022

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Osteoinductive effects of glyceollins on adult mesenchymal stromal/stem cells from adipose tissue and bone marrow

Phytomedicine (Stuttgart), 2017-04, Vol.27, p.39-51

2017

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Effects of 7-O Substitutions on Estrogenic and Anti-Estrogenic Activities of Daidzein Analogues in MCF-7 Breast Cancer Cells

Journal of medicinal chemistry, 2010-08, Vol.53 (16), p.6153-6163

2010

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Coumarins and P450s, Studies Reported to-Date

Cytochrome P450 family 1 inhibitors and structure-activity relationships

Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date

Ligands of Therapeutic Utility for the Liver X Receptors

Small molecule tyrosine kinase inhibitors of ErbB2/HER2/Neu in the treatment of aggressive breast cancer

Inhibition of Cytochrome P450 Enzymes by Quinones and Anthraquinones

Insights on cytochrome p450 enzymes and inhibitors obtained through QSAR studies

7-Ethynylcoumarins: Selective Inhibitors of Human Cytochrome P450s 1A1 and 1A2

Abstract 6360: Development of a new substituted 1,3-dioxoisoindoline series that are RPS6K1 protein kinase inhibitors as potential cancer therapeutics

Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme

Development of Flavone Propargyl Ethers as Potent and Selective Inhibitors of Cytochrome P450 Enzymes 1A1 and 1A2

Identification of New Mono/Dihydroxynaphthoquinone as Lead Agents That Inhibit the Growth of Refractive and Triple-Negative Breast Cancer Cell Lines

Design, Synthesis, and Biological Studies of Flavone-Based Esters and Acids as Potential P450 2A6 Inhibitors

Synthetic Method to Form 2,2′-Bis(naphthoquinone) Compounds

Crystal structure of 4-bromo-5,7-dimethoxy-2,3-dihydro-1 H -inden-1-one

Modification and Biological Evaluation of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion

Crystal structure of 4-bromo-5,7-dimethoxy-2,3-dihydro-1H-inden-1-one

Crystal structure of 4-bromo-5,7-dimeth-oxy-2,3-di-hydro-1H-inden-1-one

Pyranoflavones: A Group of Small-Molecule Probes for Exploring the Active Site Cavities of Cytochrome P450 Enzymes 1A1, 1A2, and 1B1

Identification of CYP 2A6 inhibitors in an effort to mitigate the harmful effects of the phytochemical nicotine

Abstract B058: Drug resistant HER2Δ16 overexpression cells are sensitive to a new class of tyrosine kinase inhibitors

Identification of quinones as novel PIM1 kinase inhibitors

Abstract 343: New derivatives of 1,3-dioxoisoindoline: Potential breast cancer therapeutics that are S6K1 inhibitors

Osteoinductive effects of glyceollins on adult mesenchymal stromal/stem cells from adipose tissue and bone marrow

Effects of 7-O Substitutions on Estrogenic and Anti-Estrogenic Activities of Daidzein Analogues in MCF-7 Breast Cancer Cells

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