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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2061-2065

2001

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Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (17), p.2241-2244

2001

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Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1959-1962

2002

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Biochemical and genetic characterization of the action of triclosan on Staphylococcus aureus

Journal of antimicrobial chemotherapy, 2001-07, Vol.48 (1), p.1-6

2001

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Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Antimicrobial Agents and Chemotherapy, 2002-10, Vol.46 (10), p.3118-3124

2002

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Nanomolar Inhibitors of Staphylococcus a ureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1959-1962

2002

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A functional origin of transfer (oriT) on the conjugative transposon Tn916

Journal of Bacteriology, 1995-11, Vol.177 (22), p.6644-6651

1995

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A novel gentamicin resistance gene in Enterococcus

Antimicrobial Agents and Chemotherapy, 1997-03, Vol.41 (3), p.511-514

1997

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Evidence that coupling sequences play a frequency-determining role in conjugative transposition of Tn916 in Enterococcus faecalis

Journal of Bacteriology, 1994-06, Vol.176 (11), p.3328-3335

1994

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Analyses oftraA, int-Tn,andxis-TnMutations in the Conjugative Transposon Tn916inEnterococcus faecalis

Plasmid, 1996-11, Vol.36 (3), p.201-208

1996

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Analyses of traA, int-Tn, and xis-Tn mutations in the conjugative transposon Tn916 in Enterococcus faecalis

Plasmid, 1996-11, Vol.36 (3), p.201-208

1996

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Mutations in Ehrlichia chaffeensis Causing Polar Effects in Gene Expression and Differential Host Specificities

PloS one, 2015-07, Vol.10 (7), p.e0132657-e0132657

2015

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Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4+ T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host

PloS one, 2016-02, Vol.11 (2), p.e0148229-e0148229

2016

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Ehrlichia chaffeensis infection in the reservoir host (white-tailed deer) and in an incidental host (dog) is impacted by its prior growth in macrophage and tick cell environments

PloS one, 2014-10, Vol.9 (10), p.e109056-e109056

2014

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Genetically modified live vaccine offers protective immunity against wild-type Anaplasma marginale tick-transmission challenge

Vaccine, 2024-06, p.126069, Article 126069

2024

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Multiple Ehrlichia chaffeensis Genes Critical for Its Persistent Infection in a Vertebrate Host Are Identified by Random Mutagenesis Coupled with In Vivo Infection Assessment

Infection and immunity, 2020-09, Vol.88 (10)

2020

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Targeted mutagenesis in Anaplasma marginale to define virulence and vaccine development against bovine anaplasmosis

PLoS pathogens, 2022-05, Vol.18 (5), p.e1010540

2022

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Attenuated Mutants of Ehrlichia chaffeensis Induce Protection against Wild-Type Infection Challenge in the Reservoir Host and in an Incidental Host

Infection and immunity, 2015-07, Vol.83 (7), p.2827-2835

2015

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Targeted and random mutagenesis of Ehrlichia chaffeensis for the identification of genes required for in vivo infection

PLoS pathogens, 2013-02, Vol.9 (2), p.e1003171

2013

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American College of Sports Medicine Expert Consensus Statement to Update Recommendations for Screening, Staffing, and Emergency Policies to Prevent Cardiovascular Events at Health Fitness Facilities

Current sports medicine reports, 2020-06, Vol.19 (6), p.223-231

2020

Volltextzugriff (PDF)

The transcriptome of the lone star tick, Amblyomma americanum, reveals molecular changes in response to infection with the pathogen, Ehrlichia chaffeensis

Journal of Asia-Pacific Entomology, 2018, 21(3), , pp.852-863

2018

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Doxycycline's Effect on Ocular Angiogenesis: An In Vivo Analysis

Ophthalmology (Rochester, Minn.), 2010-09, Vol.117 (9), p.1782-1791

2010

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Amblyomma americanum ticks infected with in vitro cultured wild-type and mutants of Ehrlichia chaffeensis are competent to produce infection in naïve deer and dogs

Ticks and tick-borne diseases, 2017-01, Vol.8 (1), p.60-64

2017

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The New ACSM Recommendations for Preventing Cardiovascular Events at Fitness Facilities

ACSM's health & fitness journal, 2020-11, Vol.24 (6), p.10-17

2020

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Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4.sup.+ T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host

PloS one, 2016-02, Vol.11 (2)

2016

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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents

Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Biochemical and genetic characterization of the action of triclosan on Staphylococcus aureus

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Nanomolar Inhibitors of Staphylococcus a ureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

A functional origin of transfer (oriT) on the conjugative transposon Tn916

A novel gentamicin resistance gene in Enterococcus

Evidence that coupling sequences play a frequency-determining role in conjugative transposition of Tn916 in Enterococcus faecalis

Analyses oftraA, int-Tn,andxis-TnMutations in the Conjugative Transposon Tn916inEnterococcus faecalis

Analyses of traA, int-Tn, and xis-Tn mutations in the conjugative transposon Tn916 in Enterococcus faecalis

Mutations in Ehrlichia chaffeensis Causing Polar Effects in Gene Expression and Differential Host Specificities

Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4+ T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host

Ehrlichia chaffeensis infection in the reservoir host (white-tailed deer) and in an incidental host (dog) is impacted by its prior growth in macrophage and tick cell environments

Genetically modified live vaccine offers protective immunity against wild-type Anaplasma marginale tick-transmission challenge

Multiple Ehrlichia chaffeensis Genes Critical for Its Persistent Infection in a Vertebrate Host Are Identified by Random Mutagenesis Coupled with In Vivo Infection Assessment

Targeted mutagenesis in Anaplasma marginale to define virulence and vaccine development against bovine anaplasmosis

Attenuated Mutants of Ehrlichia chaffeensis Induce Protection against Wild-Type Infection Challenge in the Reservoir Host and in an Incidental Host

Targeted and random mutagenesis of Ehrlichia chaffeensis for the identification of genes required for in vivo infection

American College of Sports Medicine Expert Consensus Statement to Update Recommendations for Screening, Staffing, and Emergency Policies to Prevent Cardiovascular Events at Health Fitness Facilities

The transcriptome of the lone star tick, Amblyomma americanum, reveals molecular changes in response to infection with the pathogen, Ehrlichia chaffeensis

Doxycycline's Effect on Ocular Angiogenesis: An In Vivo Analysis

Amblyomma americanum ticks infected with in vitro cultured wild-type and mutants of Ehrlichia chaffeensis are competent to produce infection in naïve deer and dogs

The New ACSM Recommendations for Preventing Cardiovascular Events at Fitness Facilities

Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4.sup.+ T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host

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