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Prodrugs: design and clinical applications

Nature reviews. Drug discovery, 2008-03, Vol.7 (3), p.255-270

2008

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Glucose Promoiety Enables Glucose Transporter Mediated Brain Uptake of Ketoprofen and Indomethacin Prodrugs in Rats

Journal of medicinal chemistry, 2009-05, Vol.52 (10), p.3348-3353

2009

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Cyclodextrins in drug delivery

Expert opinion on drug delivery, 2005-03, Vol.2 (2), p.335-351

2005

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In vitro toxicity and permeation of cyclodextrins in Calu-3 cells

Journal of controlled release, 2008-02, Vol.126 (1), p.10-16

2008

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The First Bioreversible Prodrug of Metformin with Improved Lipophilicity and Enhanced Intestinal Absorption

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4142-4148

2009

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Antibacterial activity of methylated chitosan and chitooligomer derivatives: Synthesis and structure activity relationships

European polymer journal, 2007-06, Vol.43 (6), p.2660-2671

2007

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Cyclodextrins in ophthalmic drug delivery

Advanced drug delivery reviews, 1999-03, Vol.36 (1), p.59-79

1999

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Antimicrobial activity of piperazine derivatives of chitosan

Carbohydrate polymers, 2008-11, Vol.74 (3), p.566-571

2008

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Antimicrobial activity of chitosan N-betainates

Carbohydrate polymers, 2006-07, Vol.65 (1), p.114-118

2006

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Precipitation Complexation Method Produces Cannabidiol/β-Cyclodextrin Inclusion Complex Suitable for Sublingual Administration of Cannabidiol

Journal of pharmaceutical sciences, 2007-02, Vol.96 (2), p.312-319

2007

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Ocular absorption following topical delivery

Advanced drug delivery reviews, 1995-08, Vol.16 (1), p.3-19

1995

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In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs

Journal of antimicrobial chemotherapy, 2007-10, Vol.60 (4), p.802-810

2007

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Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors

European journal of nutrition, 2006-12, Vol.45 (8), p.470-477

2006

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Development and validation of a gas chromatographic–mass spectrometric method for quantitative determination of perphenazine in rabbit plasma after sublingual administration

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-09, Vol.872 (1), p.51-57

2008

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Crystal structure changes of γ-cyclodextrin after the SEDS process in supercritical carbon dioxide affect the dissolution rate of complexed budesonide

Pharmaceutical research, 2007-06, Vol.24 (6), p.1058-1066

2007

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Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits

Journal of pharmacy and pharmacology, 2011-01, Vol.63 (1), p.19-25

2011

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Design, Synthesis, and In Vitro Evaluation of Carbamate Derivatives of 2-Benzoxazolyl- and 2-Benzothiazolyl-(3-hydroxyphenyl)-methanones as Novel Fatty Acid Amide Hydrolase Inhibitors

Journal of medicinal chemistry, 2007-08, Vol.50 (17), p.4236-4242

2007

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Fatty Acid Amide Hydrolase Inhibitors from Virtual Screening of the Endocannabinoid System

Journal of medicinal chemistry, 2006-07, Vol.49 (15), p.4650-4656

2006

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Quantitative analysis of natural cyclodextrins by high-performance liquid chromatography with pulsed amperometric detection: Application to cell permeation study

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-05, Vol.867 (1), p.90-98

2008

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Comparison of the Enzymatic Stability and Intraocular Pressure Effects of 2-Arachidonylglycerol and Noladin Ether, a Novel Putative Endocannabinoid

Investigative ophthalmology & visual science, 2002-10, Vol.43 (10), p.3216-3222

2002

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Preparation of budesonide/γ‐cyclodextrin complexes in supercritical fluids with a novel SEDS method

Journal of pharmaceutical sciences, 2006-10, Vol.95 (10), p.2235-2245

2006

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Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line

Pharmaceutical research, 1998-08, Vol.15 (8), p.1275-1280

1998

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N-(3-(4-Hydroxyphenyl)-propenoyl)-amino acid tryptamides as SIRT2 inhibitors

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (9), p.2448-2451

2007

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N,N‘-Bisbenzylidenebenzene-1,4-diamines and N,N‘-Bisbenzylidenenaphthalene-1,4-diamines as Sirtuin Type 2 (SIRT2) Inhibitors

Journal of medicinal chemistry, 2006-12, Vol.49 (26), p.7907-7911

2006

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Synthesis, in vitro and in vivo characterization of novel ethyl dioxy phosphate prodrug of propofol

European journal of pharmaceutical sciences, 2008-07, Vol.34 (2), p.110-117

2008

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Prodrugs: design and clinical applications

Glucose Promoiety Enables Glucose Transporter Mediated Brain Uptake of Ketoprofen and Indomethacin Prodrugs in Rats

Cyclodextrins in drug delivery

In vitro toxicity and permeation of cyclodextrins in Calu-3 cells

The First Bioreversible Prodrug of Metformin with Improved Lipophilicity and Enhanced Intestinal Absorption

Antibacterial activity of methylated chitosan and chitooligomer derivatives: Synthesis and structure activity relationships

Cyclodextrins in ophthalmic drug delivery

Antimicrobial activity of piperazine derivatives of chitosan

Antimicrobial activity of chitosan N-betainates

Precipitation Complexation Method Produces Cannabidiol/β-Cyclodextrin Inclusion Complex Suitable for Sublingual Administration of Cannabidiol

Ocular absorption following topical delivery

In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs

Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors

Development and validation of a gas chromatographic–mass spectrometric method for quantitative determination of perphenazine in rabbit plasma after sublingual administration

Crystal structure changes of γ-cyclodextrin after the SEDS process in supercritical carbon dioxide affect the dissolution rate of complexed budesonide

Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits

Design, Synthesis, and In Vitro Evaluation of Carbamate Derivatives of 2-Benzoxazolyl- and 2-Benzothiazolyl-(3-hydroxyphenyl)-methanones as Novel Fatty Acid Amide Hydrolase Inhibitors

Fatty Acid Amide Hydrolase Inhibitors from Virtual Screening of the Endocannabinoid System

Quantitative analysis of natural cyclodextrins by high-performance liquid chromatography with pulsed amperometric detection: Application to cell permeation study

Comparison of the Enzymatic Stability and Intraocular Pressure Effects of 2-Arachidonylglycerol and Noladin Ether, a Novel Putative Endocannabinoid

Preparation of budesonide/γ‐cyclodextrin complexes in supercritical fluids with a novel SEDS method

Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line

N-(3-(4-Hydroxyphenyl)-propenoyl)-amino acid tryptamides as SIRT2 inhibitors

N,N‘-Bisbenzylidenebenzene-1,4-diamines and N,N‘-Bisbenzylidenenaphthalene-1,4-diamines as Sirtuin Type 2 (SIRT2) Inhibitors

Synthesis, in vitro and in vivo characterization of novel ethyl dioxy phosphate prodrug of propofol

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