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Bile acid receptors as targets for drug development

Nature reviews. Gastroenterology & hepatology, 2014-01, Vol.11 (1), p.55-67

2014

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The ascending pathophysiology of cholestatic liver disease

Hepatology (Baltimore, Md.), 2017-02, Vol.65 (2), p.722-738

2017

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Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma

Journal of hepatology, 2012-06, Vol.56 (6), p.1371-1383

2012

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Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration

Hepatology communications, 2021-08, Vol.5 (8), p.1400-1411

2021

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Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Hepatology (Baltimore, Md.), 2019-02, Vol.69 (2), p.666-683

2019

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Increased cancer risk after liver transplantation: a population-based study

Journal of hepatology, 2001, Vol.34 (1), p.84-91

2001

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Surveillance for hepatocellular carcinoma is associated with increased survival: Results from a large cohort in the Netherlands

Journal of hepatology, 2015-11, Vol.63 (5), p.1156-1163

2015

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The Genetic Basis of the Reduced Expression of Bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's Syndrome

The New England journal of medicine, 1995-11, Vol.333 (18), p.1171-1175

1995

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Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs

Hepatology (Baltimore, Md.), 2012-03, Vol.55 (3), p.821-832

2012

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Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation

Journal of hepatology, 2003-08, Vol.39 (2), p.153-161

2003

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Fibroblast growth factor 21 is induced by endoplasmic reticulum stress

Biochimie, 2013-04, Vol.95 (4), p.692-699

2013

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Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis

Journal of hepatology, 2017-06, Vol.66 (6), p.1214-1222

2017

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A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump

Journal of hepatology, 2004, Vol.40 (1), p.24-30

2004

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Hepatocellular carcinoma in cirrhotic versus noncirrhotic livers: results from a large cohort in the Netherlands

European journal of gastroenterology & hepatology, 2016-03, Vol.28 (3), p.352-359

2016

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Pituitary TSH controls bile salt synthesis

Journal of hepatology, 2015-05, Vol.62 (5), p.1005-1007

2015

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Endogenous bile acids as carcinogens

Journal of hepatology, 2007-09, Vol.47 (3), p.434-435

Jansen, Peter L.M

2007

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Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

Gastroenterology (New York, N.Y. 1943), 2004-08, Vol.127 (2), p.379-384

2004

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Hepatocellular carcinoma in noncirrhotic livers is associated with steatosis rather than steatohepatitis: potential implications for pathogenesis

European journal of gastroenterology & hepatology, 2016-08, Vol.28 (8), p.955-962

2016

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Drug transport proteins in the liver

Advanced drug delivery reviews, 2003-01, Vol.55 (1), p.107-124

2003

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Lifestyle intervention for non-alcoholic fatty liver disease: prospective cohort study of its efficacy and factors related to improvement

Archives of disease in childhood, 2011-07, Vol.96 (7), p.669-674

2011

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A new life for bile acids

Journal of hepatology, 2010-06, Vol.52 (6), p.937-938

Jansen, Peter L.M

2010

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Hepatitis C testing and treatment among active drug users in Amsterdam: results from the DUTCH-C project

European journal of gastroenterology & hepatology, 2011-01, Vol.23 (1), p.23-31

2011

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Decreased P‐glycoprotein (P‐gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels

Inflammatory bowel diseases, 2007-06, Vol.13 (6), p.710-720

2007

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Transient elevation of serum bile salts after partial hepatectomy is due to metabolic overload and not to cholestasis

Journal of hepatology, 2012-03, Vol.56 (3), p.743-744

Jansen, Peter L.M

2012

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Prometheus’ little helper, a novel role for fibroblast growth factor 15 in compensatory liver growth

Journal of hepatology, 2013-11, Vol.59 (5), p.1121-1123

2013

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Bile acid receptors as targets for drug development

The ascending pathophysiology of cholestatic liver disease

Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma

Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Increased cancer risk after liver transplantation: a population-based study

Surveillance for hepatocellular carcinoma is associated with increased survival: Results from a large cohort in the Netherlands

The Genetic Basis of the Reduced Expression of Bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's Syndrome

Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs

Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation

Fibroblast growth factor 21 is induced by endoplasmic reticulum stress

Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis

A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump

Hepatocellular carcinoma in cirrhotic versus noncirrhotic livers: results from a large cohort in the Netherlands

Pituitary TSH controls bile salt synthesis

Endogenous bile acids as carcinogens

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

Hepatocellular carcinoma in noncirrhotic livers is associated with steatosis rather than steatohepatitis: potential implications for pathogenesis

Drug transport proteins in the liver

Lifestyle intervention for non-alcoholic fatty liver disease: prospective cohort study of its efficacy and factors related to improvement

A new life for bile acids

Hepatitis C testing and treatment among active drug users in Amsterdam: results from the DUTCH-C project

Decreased P‐glycoprotein (P‐gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels

Transient elevation of serum bile salts after partial hepatectomy is due to metabolic overload and not to cholestasis

Prometheus’ little helper, a novel role for fibroblast growth factor 15 in compensatory liver growth

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