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Bile acid receptors as targets for drug development

Nature reviews. Gastroenterology & hepatology, 2014-01, Vol.11 (1), p.55-67

2014

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The ascending pathophysiology of cholestatic liver disease

Hepatology (Baltimore, Md.), 2017-02, Vol.65 (2), p.722-738

2017

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Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma

Journal of hepatology, 2012-06, Vol.56 (6), p.1371-1383

2012

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Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Hepatology (Baltimore, Md.), 2019-02, Vol.69 (2), p.666-683

2019

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Surveillance for hepatocellular carcinoma is associated with increased survival: Results from a large cohort in the Netherlands

Journal of hepatology, 2015-11, Vol.63 (5), p.1156-1163

2015

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Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs

Hepatology (Baltimore, Md.), 2012-03, Vol.55 (3), p.821-832

2012

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Fibroblast growth factor 21 is induced by endoplasmic reticulum stress

Biochimie, 2013-04, Vol.95 (4), p.692-699

2013

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Increased cancer risk after liver transplantation: a population-based study

Journal of hepatology, 2001, Vol.34 (1), p.84-91

2001

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Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis

Journal of hepatology, 2017-06, Vol.66 (6), p.1214-1222

2017

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Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation

Journal of hepatology, 2003-08, Vol.39 (2), p.153-161

2003

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The Genetic Basis of the Reduced Expression of Bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's Syndrome

The New England journal of medicine, 1995-11, Vol.333 (18), p.1171-1175

1995

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Hepatocellular carcinoma in cirrhotic versus noncirrhotic livers: results from a large cohort in the Netherlands

European journal of gastroenterology & hepatology, 2016-03, Vol.28 (3), p.352-359

2016

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A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump

Journal of hepatology, 2004, Vol.40 (1), p.24-30

2004

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Pituitary TSH controls bile salt synthesis

Journal of hepatology, 2015-05, Vol.62 (5), p.1005-1007

2015

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Hepatocellular carcinoma in noncirrhotic livers is associated with steatosis rather than steatohepatitis: potential implications for pathogenesis

European journal of gastroenterology & hepatology, 2016-08, Vol.28 (8), p.955-962

2016

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Endogenous bile acids as carcinogens

Journal of hepatology, 2007-09, Vol.47 (3), p.434-435

Jansen, Peter L.M

2007

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Lifestyle intervention for non-alcoholic fatty liver disease: prospective cohort study of its efficacy and factors related to improvement

Archives of disease in childhood, 2011-07, Vol.96 (7), p.669-674

2011

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Hepatitis C testing and treatment among active drug users in Amsterdam: results from the DUTCH-C project

European journal of gastroenterology & hepatology, 2011-01, Vol.23 (1), p.23-31

2011

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A new life for bile acids

Journal of hepatology, 2010-06, Vol.52 (6), p.937-938

Jansen, Peter L.M

2010

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Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

Gastroenterology (New York, N.Y. 1943), 2004-08, Vol.127 (2), p.379-384

2004

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Transient elevation of serum bile salts after partial hepatectomy is due to metabolic overload and not to cholestasis

Journal of hepatology, 2012-03, Vol.56 (3), p.743-744

Jansen, Peter L.M

2012

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Decreased P‐glycoprotein (P‐gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels

Inflammatory bowel diseases, 2007-06, Vol.13 (6), p.710-720

2007

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Drug transport proteins in the liver

Advanced drug delivery reviews, 2003-01, Vol.55 (1), p.107-124

2003

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Prometheus’ little helper, a novel role for fibroblast growth factor 15 in compensatory liver growth

Journal of hepatology, 2013-11, Vol.59 (5), p.1121-1123

2013

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Progressive familial intrahepatic cholestasis type 1

Seminars in liver disease, 2010-05, Vol.30 (2), p.117-124

2010

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Bile acid receptors as targets for drug development

The ascending pathophysiology of cholestatic liver disease

Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Surveillance for hepatocellular carcinoma is associated with increased survival: Results from a large cohort in the Netherlands

Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs

Fibroblast growth factor 21 is induced by endoplasmic reticulum stress

Increased cancer risk after liver transplantation: a population-based study

Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis

Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation

The Genetic Basis of the Reduced Expression of Bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's Syndrome

Hepatocellular carcinoma in cirrhotic versus noncirrhotic livers: results from a large cohort in the Netherlands

A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump

Pituitary TSH controls bile salt synthesis

Hepatocellular carcinoma in noncirrhotic livers is associated with steatosis rather than steatohepatitis: potential implications for pathogenesis

Endogenous bile acids as carcinogens

Lifestyle intervention for non-alcoholic fatty liver disease: prospective cohort study of its efficacy and factors related to improvement

Hepatitis C testing and treatment among active drug users in Amsterdam: results from the DUTCH-C project

A new life for bile acids

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

Transient elevation of serum bile salts after partial hepatectomy is due to metabolic overload and not to cholestasis

Decreased P‐glycoprotein (P‐gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels

Drug transport proteins in the liver

Prometheus’ little helper, a novel role for fibroblast growth factor 15 in compensatory liver growth

Progressive familial intrahepatic cholestasis type 1

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