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Structural basis for specific inhibition of the deubiquitinase UCHL1

Nature communications, 2022-10, Vol.13 (1), p.5950-5950, Article 5950

2022

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Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation

eLife, 2021-12, Vol.10

2021

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Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

Angewandte Chemie International Edition, 2020-03, Vol.59 (14), p.5721-5729

International ed. in English, 2020

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Covalent-Allosteric Kinase Inhibitors

Angewandte Chemie International Edition, 2015-08, Vol.54 (35), p.10313-10316

International ed. in English, 2015

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Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics

Bioscience, biotechnology, and biochemistry, 2020-12, Vol.84 (12), p.2484-2490

2020

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Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease

PloS one, 2018-05, Vol.13 (5), p.e0197659

2018

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Natural product-inspired cascade synthesis yields modulators of centrosome integrity

Nature chemical biology, 2011-12, Vol.8 (2), p.179-184

2011

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Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors

eLife, 2023-03, Vol.12

2023

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Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

Angewandte Chemie International Edition, 2011-10, Vol.50 (42), p.9838-9842

2011

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Molecular uptake of chitooligosaccharides through chitoporin from the marine bacterium Vibrio harveyi

PloS one, 2013-01, Vol.8 (1), p.e55126-e55126

2013

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2‐Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation

European journal of organic chemistry, 2019-09, Vol.2019 (31-32), p.5486-5496

2019

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Hypertonicity‐induced cation channels in HepG2 cells: architecture and role in proliferation vs. apoptosis

The Journal of physiology, 2018-04, Vol.596 (7), p.1227-1241

2018

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Concepts and case studies in chemical biology

Herbert Waldmann, Petra Janning

2, 2014

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PhzA/B Catalyzes the Formation of the Tricycle in Phenazine Biosynthesis

Journal of the American Chemical Society, 2008-12, Vol.130 (50), p.17053-17061

2008

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Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1

PloS one, 2014-07, Vol.9 (7), p.e102425

2014

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14-3-3 Protein Bmh1 triggers short-range compaction of mitotic chromosomes by recruiting sirtuin deacetylase Hst2

The Journal of biological chemistry, 2021-01, Vol.296, p.100078-100078, Article 100078

2021

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Small-Molecule Target Engagement in Cells

Cell chemical biology, 2016-04, Vol.23 (4), p.435-441

2016

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Structure and Function of the Phenazine Biosynthetic Protein PhzF from Pseudomonas fluorescens

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (47), p.16431-16436

2004

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A pull-down procedure for the identification of unknown GEFs for small GTPases

Small GTPases, 2016-04, Vol.7 (2), p.93-106

2016

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Development of a PDEδ‐Targeting PROTACs that Impair Lipid Metabolism

Angewandte Chemie International Edition, 2020-03, Vol.59 (14), p.5595-5601

International ed. in English, 2020

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Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36

Nature chemical biology, 2023-11, Vol.19 (11), p.1394-1405

2023

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Ras Pathway Modulator Melophlin A Targets Dynamins

Angewandte Chemie (International ed.), 2009-01, Vol.48 (39), p.7240-7245

2009

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Identification of Ustilago maydis Aurora Kinase As a Novel Antifungal Target

ACS chemical biology, 2011-09, Vol.6 (9), p.926-933

2011

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Covalent Protein Labeling at Glutamic Acids

Cell chemical biology, 2017-05, Vol.24 (5), p.589-597.e5

2017

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A hydroxylamine probe for profiling S-acylated fatty acids on proteins

Chemical communications (Cambridge, England), 2019-09, Vol.55 (75), p.11183-11186

2019

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Structural basis for specific inhibition of the deubiquitinase UCHL1

Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

Covalent-Allosteric Kinase Inhibitors

Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease

Natural product-inspired cascade synthesis yields modulators of centrosome integrity

Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

Molecular uptake of chitooligosaccharides through chitoporin from the marine bacterium Vibrio harveyi

2‐Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation

Hypertonicity‐induced cation channels in HepG2 cells: architecture and role in proliferation vs. apoptosis

Concepts and case studies in chemical biology

PhzA/B Catalyzes the Formation of the Tricycle in Phenazine Biosynthesis

Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1

14-3-3 Protein Bmh1 triggers short-range compaction of mitotic chromosomes by recruiting sirtuin deacetylase Hst2

Small-Molecule Target Engagement in Cells

Structure and Function of the Phenazine Biosynthetic Protein PhzF from Pseudomonas fluorescens

A pull-down procedure for the identification of unknown GEFs for small GTPases

Development of a PDEδ‐Targeting PROTACs that Impair Lipid Metabolism

Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36

Ras Pathway Modulator Melophlin A Targets Dynamins

Identification of Ustilago maydis Aurora Kinase As a Novel Antifungal Target

Covalent Protein Labeling at Glutamic Acids

A hydroxylamine probe for profiling S-acylated fatty acids on proteins

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