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RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3

Cell, 2014-05, Vol.157 (5), p.1189-1202

2014

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The many faces of mouse histiocytic sarcoma in C57BL/6J mice

Veterinary pathology, 2023-07, Vol.60 (4), p.443

2023

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Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (27), p.11199-11204

2013

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Survival Function of the FADD-CASPASE-8-cFLIPL Complex

Cell reports (Cambridge), 2012-05, Vol.1 (5), p.401-407

2012

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Crenolanib is active against models of drug-resistant FLT3-ITD−positive acute myeloid leukemia

Blood, 2013-11, Vol.122 (22), p.3607-3615

2013

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Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis

Cell reports (Cambridge), 2013-10, Vol.5 (2), p.340-348

2013

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Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.5231-5236

2015

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Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model

PloS one, 2016-03, Vol.11 (3), p.e0151433

2016

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Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice

The Journal of clinical investigation, 2022-11, Vol.132 (21), p.1-14

2022

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Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy

Blood, 2018-05, Vol.131 (22), p.2466-2474

2018

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Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function

Immunity (Cambridge, Mass.), 2016-01, Vol.44 (1), p.88-102

2016

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The interaction between RIPK1 and FADD controls perinatal lethality and inflammation

Cell reports (Cambridge), 2024-06, Vol.43 (6), p.114335-114335, Article 114335

2024

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Cisplatin-Induced Renal Injury Is Independently Mediated by OCT2 and p53

Clinical cancer research, 2014-08, Vol.20 (15), p.4026-4035

2014

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Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models

PloS one, 2019-05, Vol.14 (5), p.e0216328

2019

Volltextzugriff (PDF)

Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL)

Scientific reports, 2021-03, Vol.11 (1), p.5154-5154, Article 5154

2021

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Primary Epiphyseal Arteriopathy in a Mouse Model of Steroid-Induced Osteonecrosis

The American journal of pathology, 2013-07, Vol.183 (1), p.19-25

2013

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Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia

PloS one, 2015-08, Vol.10 (8), p.e0135134

2015

Volltextzugriff (PDF)

NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs

Cell, 2023-06, Vol.186 (13), p.2783-2801.e20

2023

Volltextzugriff (PDF)

ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia

Blood cancer discovery, 2022-05, Vol.3 (3), p.240

2022

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Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

Clinical and translational science, 2021-07, Vol.14 (4), p.1490-1504

2021

Volltextzugriff (PDF)

3’ UTR-truncated HMGA2 overexpression induces non-malignant in vivo expansion of hematopoietic stem cells in non-human primates

Molecular therapy. Methods & clinical development, 2021-06, Vol.21, p.693-701

2021

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Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis

JCI insight, 2017-08, Vol.2 (15)

2017

Volltextzugriff (PDF)

Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis

Immunity (Cambridge, Mass.), 2020-06, Vol.52 (6), p.994-1006.e8

2020

Volltextzugriff (PDF)

Host thiopurine methyltransferase status affects mercaptopurine antileukemic effectiveness in a murine model

Pharmacogenetics and genomics, 2014-05, Vol.24 (5), p.263-271

2014

Volltextzugriff (PDF)

The genetic basis and cell of origin of mixed phenotype acute leukaemia

Nature (London), 2018-10, Vol.562 (7727), p.373-379

2018

Volltextzugriff (PDF)

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RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3

The many faces of mouse histiocytic sarcoma in C57BL/6J mice

Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

Survival Function of the FADD-CASPASE-8-cFLIPL Complex

Crenolanib is active against models of drug-resistant FLT3-ITD−positive acute myeloid leukemia

Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis

Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model

Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice

Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy

Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function

The interaction between RIPK1 and FADD controls perinatal lethality and inflammation

Cisplatin-Induced Renal Injury Is Independently Mediated by OCT2 and p53

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models

Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL)

Primary Epiphyseal Arteriopathy in a Mouse Model of Steroid-Induced Osteonecrosis

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia

NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs

ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

3’ UTR-truncated HMGA2 overexpression induces non-malignant in vivo expansion of hematopoietic stem cells in non-human primates

Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis

Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis

Host thiopurine methyltransferase status affects mercaptopurine antileukemic effectiveness in a murine model

The genetic basis and cell of origin of mixed phenotype acute leukaemia

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