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Steroid catabolism in marine and freshwater fish

The Journal of steroid biochemistry and molecular biology, 2011-11, Vol.127 (3), p.167-175

James, Margaret O.

2011

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Triclosan is a potent inhibitor of estradiol and estrone sulfonation in sheep placenta

Environment international, 2010-11, Vol.36 (8), p.942-949

2010

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Slow O-demethylation of methyl triclosan to triclosan, which is rapidly glucuronidated and sulfonated in channel catfish liver and intestine

Aquatic toxicology, 2012-11, Vol.124-125, p.72-82

2012

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Triclosan as a substrate and inhibitor of 3'-phosphoadenosine 5'-phosphosulfate-sulfotransferase and UDP-glucuronosyl transferase in human liver fractions

Drug metabolism and disposition, 2004-10, Vol.32 (10), p.1162-1169

2004

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Genomic Effect of Triclosan on the Fetal Hypothalamus: Evidence for Altered Neuropeptide Regulation

Endocrinology (Philadelphia), 2016-07, Vol.157 (7), p.2686-2697

2016

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Editorial: Translational Research and Drug Repurposing for Non-Communicable Diseases (NCDs)

Frontiers in pharmacology, 2022-03, Vol.13, p.879611-879611

2022

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Interactions of cytosolic sulfotransferases with xenobiotics

Drug metabolism reviews, 2013-11, Vol.45 (4), p.401-414

2013

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Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1

Pharmacology & therapeutics (Oxford), 2017-02, Vol.170, p.166-180

2017

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Efficacy data of halogenated phenazine and quinoline agents and an NH125 analogue to veterinary mycoplasmas

BMC veterinary research, 2020-04, Vol.16 (1), p.107-11, Article 107

2020

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The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression

Pharmacogenetics and genomics, 2015-05, Vol.25 (5), p.239-245

2015

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state of in vitro science for use in bioaccumulation assessments for fish

Environmental toxicology and chemistry, 2009, Vol.28 (1), p.86-96

2009

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Sulfonation and glucuronidation of hydroxylated bromodiphenyl ethers in human liver

Chemosphere (Oxford), 2019-07, Vol.226, p.132-139

2019

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Age-dependent kinetics and metabolism of dichloroacetate: possible relevance to toxicity

The Journal of pharmacology and experimental therapeutics, 2008-03, Vol.324 (3), p.1163-1171

2008

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Phase II metabolism of betulin by rat and human UDP-glucuronosyltransferases and sulfotransferases

Chemico-biological interactions, 2019-04, Vol.302, p.190-195

2019

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Model Informed Dose Optimization of Dichloroacetate for the Treatment of Congenital Lactic Acidosis in Children

Journal of clinical pharmacology, 2018-02, Vol.58 (2), p.212-220

2018

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Pharmacogenetic considerations with dichloroacetate dosing

Pharmacogenomics, 2016-05, Vol.17 (7), p.743-753

2016

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Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine

Drug metabolism and disposition, 2008-04, Vol.36 (4), p.623-630

2008

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Sulfonation of environmental chemicals and their metabolites in the polar bear (Ursus maritimus)

Drug metabolism and disposition, 2005-09, Vol.33 (9), p.1341-1348

2005

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Hepatic demethylation of methoxy-bromodiphenyl ethers and conjugation of the resulting hydroxy-bromodiphenyl ethers in a marine fish, the red snapper, Lutjanus campechanus, and a freshwater fish, the channel catfish, Ictalurus punctatus

Chemosphere (Oxford), 2022-01, Vol.286, p.131620-131620, Article 131620

2022

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Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate

The Journal of steroid biochemistry and molecular biology, 2005-09, Vol.96 (5), p.367-374

2005

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Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes

Drug metabolism and disposition, 2006-06, Vol.34 (6), p.932-938

2006

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Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1

Drug metabolism and disposition, 2020-11, Vol.48 (11), p.1224-1230

2020

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Administration of low dose triclosan to pregnant ewes results in placental uptake and reduced estradiol sulfotransferase activity in fetal liver and placenta

Toxicology letters, 2018-09, Vol.294, p.116-121

2018

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Pharmacokinetic and Biochemical Profiling of Sodium Dichloroacetate in Pregnant Ewes and Fetuses

Drug metabolism and disposition, 2021-06, Vol.49 (6), p.451-458

2021

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A Mechanism-Based Pharmacokinetic Enzyme Turnover Model for Dichloroacetic Acid Autoinhibition in Rats

Journal of pharmaceutical sciences, 2017-05, Vol.106 (5), p.1396-1404

2017

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Steroid catabolism in marine and freshwater fish

Triclosan is a potent inhibitor of estradiol and estrone sulfonation in sheep placenta

Slow O-demethylation of methyl triclosan to triclosan, which is rapidly glucuronidated and sulfonated in channel catfish liver and intestine

Triclosan as a substrate and inhibitor of 3'-phosphoadenosine 5'-phosphosulfate-sulfotransferase and UDP-glucuronosyl transferase in human liver fractions

Genomic Effect of Triclosan on the Fetal Hypothalamus: Evidence for Altered Neuropeptide Regulation

Editorial: Translational Research and Drug Repurposing for Non-Communicable Diseases (NCDs)

Interactions of cytosolic sulfotransferases with xenobiotics

Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1

Efficacy data of halogenated phenazine and quinoline agents and an NH125 analogue to veterinary mycoplasmas

The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression

state of in vitro science for use in bioaccumulation assessments for fish

Sulfonation and glucuronidation of hydroxylated bromodiphenyl ethers in human liver

Age-dependent kinetics and metabolism of dichloroacetate: possible relevance to toxicity

Phase II metabolism of betulin by rat and human UDP-glucuronosyltransferases and sulfotransferases

Model Informed Dose Optimization of Dichloroacetate for the Treatment of Congenital Lactic Acidosis in Children

Pharmacogenetic considerations with dichloroacetate dosing

Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine

Sulfonation of environmental chemicals and their metabolites in the polar bear (Ursus maritimus)

Hepatic demethylation of methoxy-bromodiphenyl ethers and conjugation of the resulting hydroxy-bromodiphenyl ethers in a marine fish, the red snapper, Lutjanus campechanus, and a freshwater fish, the channel catfish, Ictalurus punctatus

Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate

Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes

Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1

Administration of low dose triclosan to pregnant ewes results in placental uptake and reduced estradiol sulfotransferase activity in fetal liver and placenta

Pharmacokinetic and Biochemical Profiling of Sodium Dichloroacetate in Pregnant Ewes and Fetuses

A Mechanism-Based Pharmacokinetic Enzyme Turnover Model for Dichloroacetic Acid Autoinhibition in Rats

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