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Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

Annals of the rheumatic diseases, 2011-11, Vol.70 (11), p.2029-2036

2011

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A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth

Oncogene, 2012-03, Vol.31 (12), p.1558-1570

2012

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Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis

Genes and immunity, 2012-04, Vol.13 (3), p.207-213

2012

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Pharmacogenomics and Translational Simulations to Bridge Indications for an Anti-Interferon-α Receptor Antibody

Clinical pharmacology and therapeutics, 2013-06, Vol.93 (6), p.483-492

2013

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AB0814 Molecular profiling to diagnose a case of atypical dermatomyositis

Annals of the rheumatic diseases, 2013-06, Vol.71 (Suppl 3), p.685-685

2013

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OP0255 Inhibition of the Plasma Cell Signature Correlates with Reduced Collagen Expression in Systemic Sclerosis

Annals of the rheumatic diseases, 2013-06, Vol.72 (Suppl 3), p.A139-A139

2013

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Heregulin‐dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3

The EMBO journal, 1995-09, Vol.14 (17), p.4267-4275

1995

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SAT0020 Molecular characterization of collagen in muscle of polymyositis and dermatomyositis

Annals of the rheumatic diseases, 2013-06, Vol.71 (Suppl 3), p.477-478

2013

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SAT0004 Genomic signatures characterize leukocyte infiltration in myositis muscles

Annals of the rheumatic diseases, 2013-06, Vol.71 (Suppl 3), p.472-472

2013

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THU0005 Investigating the Plasma Cell Signature in Autoimmune Disease

Annals of the rheumatic diseases, 2013-06, Vol.72 (Suppl 3), p.A166-A166

2013

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Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression

Molecular and Cellular Biology, 1996-06, Vol.16 (6), p.3066-3073

1996

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The secreted tumor-associated antigen 90K is a potent immune stimulator

The Journal of biological chemistry, 1994-07, Vol.269 (28), p.18401-18407

1994

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Protein tyrosine phosphatases: their role in insulin action and potential as drug targets

Expert opinion on investigational drugs, 1999-02, Vol.8 (2), p.139-160

1999

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Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNα antibody, in systemic lupus erythematosus

Arthritis research & therapy, 2010-01, Vol.12 Suppl 1 (Suppl 1), p.S6-S6

2010

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Cloning and sequencing of porcine LH-hCG receptor cDNA: variants lacking transmembrane domain

Science (American Association for the Advancement of Science), 1989-08, Vol.245 (4917), p.525-528

1989

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Requirement for PAK4 in the Anchorage-independent Growth of Human Cancer Cell Lines

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.550-558

2002

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PAK4 mediates morphological changes through the regulation of GEF-H1

Journal of cell science, 2005-05, Vol.118 (9), p.1861-1872

2005

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100 Inhibition of PDGFRalpha in tumor stroma with MEDI-575 enhances activity of carboplatin/paclitaxel and delays tumor regrowth in a NSCLC xenograft model

European journal of cancer supplements, 2010, Vol.8 (7), p.39-39

2010

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57 Glioblastoma multiforme is characterized by high incidence of PDGFRalpha expression and susceptibility to the PDGFRalphaspecific antibody MEDI-575 in mouse tumor models

European journal of cancer supplements, 2010, Vol.8 (7), p.27-27

2010

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The Serine/Threonine Kinase Nek6 Is Required for Cell Cycle Progression through Mitosis

The Journal of biological chemistry, 2003-12, Vol.278 (52), p.52454-52460

2003

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The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Molecular and Cellular Biology, 2003-03, Vol.23 (6), p.2068-2082

2003

Volltextzugriff (PDF)

Tyrosine phosphatase inhibition permits analysis of signal transduction complexes in p185HER2/neu-overexpressing human tumor cells

The Journal of biological chemistry, 1992-03, Vol.267 (7), p.4357-4363

1992

Volltextzugriff (PDF)

The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)

Oncogene, 2002-10, Vol.21 (46), p.7067-7076

2002

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The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation

Experimental hematology, 2002-03, Vol.30 (3), p.237-244

2002

Volltextzugriff (PDF)

Structure-Based design and discovery of novel inhibitors of protein tyrosine phosphatases

Bioorganic & medicinal chemistry, 2003-04, Vol.11 (8), p.1835-1849

2003

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Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth

Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis

Pharmacogenomics and Translational Simulations to Bridge Indications for an Anti-Interferon-α Receptor Antibody

AB0814 Molecular profiling to diagnose a case of atypical dermatomyositis

OP0255 Inhibition of the Plasma Cell Signature Correlates with Reduced Collagen Expression in Systemic Sclerosis

Heregulin‐dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3

SAT0020 Molecular characterization of collagen in muscle of polymyositis and dermatomyositis

SAT0004 Genomic signatures characterize leukocyte infiltration in myositis muscles

THU0005 Investigating the Plasma Cell Signature in Autoimmune Disease

Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression

The secreted tumor-associated antigen 90K is a potent immune stimulator

Protein tyrosine phosphatases: their role in insulin action and potential as drug targets

Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNα antibody, in systemic lupus erythematosus

Cloning and sequencing of porcine LH-hCG receptor cDNA: variants lacking transmembrane domain

Requirement for PAK4 in the Anchorage-independent Growth of Human Cancer Cell Lines

PAK4 mediates morphological changes through the regulation of GEF-H1

100 Inhibition of PDGFRalpha in tumor stroma with MEDI-575 enhances activity of carboplatin/paclitaxel and delays tumor regrowth in a NSCLC xenograft model

57 Glioblastoma multiforme is characterized by high incidence of PDGFRalpha expression and susceptibility to the PDGFRalphaspecific antibody MEDI-575 in mouse tumor models

The Serine/Threonine Kinase Nek6 Is Required for Cell Cycle Progression through Mitosis

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Tyrosine phosphatase inhibition permits analysis of signal transduction complexes in p185HER2/neu-overexpressing human tumor cells

The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)

The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation

Structure-Based design and discovery of novel inhibitors of protein tyrosine phosphatases

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