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Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist

The Journal of pharmacology and experimental therapeutics, 2007-08, Vol.322 (2), p.477-485

2007

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Discovery of 2-Hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist

Journal of medicinal chemistry, 2006-12, Vol.49 (26), p.7603-7606

2006

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Minimum significant ratio of selectivity ratios (MSRSR) and confidence in ratio of selectivity ratios (CRSR): quantitative measures for selectivity ratios obtained by screening assays

Journal of biomolecular screening, 2012-08, Vol.17 (7), p.857-867

2012

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3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists

Bioorganic & medicinal chemistry, 2008, Vol.18 (1), p.228-231

2008

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The synthesis of substituted bipiperidine amide compounds as CCR3 antagonists

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1375-1378

2005

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Identification of full, partial and inverse CC chemokine receptor 3 agonists using [ 35S]GTPγS binding

European journal of pharmacology, 2002-12, Vol.456 (1), p.1-10

2002

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Receptor reserve analysis of the human CCR3 receptor in eosinophils and CCR3-transfected cells

Journal of leukocyte biology, 2000-03, Vol.67 (3), p.441-447

2000

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Pertussis Toxin Inhibition of B Cell and Macrophage Responses to Bacterial Lipopolysaccharide

Science (American Association for the Advancement of Science), 1986-11, Vol.234 (4777), p.743-746

1986

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Identification of Differentially Expressed Genes in a Monkey Model of Allergic Asthma by Microarray Technology

Chest, 2002-03, Vol.121 (3), p.26S-27S

2002

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Effects of Cyclosporin A and Dinactin on T-Cell Proliferation, Interleukin-5 Production, and Murine Pulmonary Inflammation

American journal of respiratory cell and molecular biology, 1999-03, Vol.20 (3), p.481-492

1999

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C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (13), p.3778-3783

2007

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Synthesis and structure–activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1318-1322

2008

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The synthesis of substituted bipiperidine amide compounds as CCR3 ligands: Antagonists versus agonists

Bioorganic & medicinal chemistry letters, 2005-06, Vol.15 (12), p.3020-3023

2005

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Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding

European journal of pharmacology, 2002-12, Vol.456 (1-3), p.1-10

2002

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Postjunctional α2C-adrenoceptor contractility in human saphenous vein

European journal of pharmacology, 2001-02, Vol.413 (2-3), p.263-269

2001

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B-Lymphocyte Signal Transduction in Response to Anti-Immunoglobulin and Bacterial Lipopolysaccharide

Immunological reviews, 1987-02, Vol.95 (1), p.161-176

1987

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Postjunctional α 2C-adrenoceptor contractility in human saphenous vein

European journal of pharmacology, 2001, Vol.413 (2), p.263-269

2001

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Cytokine Inhibition by A Novel Steroid, Mometasone Furoate

Immunopharmacology and immunotoxicology, 1991, Vol.13 (3), p.251-261

1991

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Pertussis toxin inhibition of B cell and macrophage response to bacterial lipopolysaccharide

Science (American Association for the Advancement of Science), 1986-11, Vol.234, p.743

1986

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Synthesis of dibenzo[a,d]cycloheptanes as cytokine biosynthesis inhibitors

Bioorganic & medicinal chemistry letters, 1995-11, Vol.5 (22), p.2749-2754

1995

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[45] The hazards of mycoplasma contamination in the screening of hybridoma supernatants for effects on [ 3H]thymidine incorporation

Methods in Enzymology, 1986, Vol.121, p.481-484

Jakway, James P.

1986

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Suppression of in vitro cytotoxic response by macrophages due to induced arginase

The Journal of experimental medicine, 1977-09, Vol.146 (3), p.665-672

1977

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Stimulation of T-cell activation by UV-treated, antigen-pulsed macrophages: Evidence for a requirement for antigen processing and interleukin 1 secretion

Cellular immunology, 1983-08, Vol.80 (1), p.151-162

1983

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SERUM FACTORS REQUIRED FOR THE IN VITRO INDUCTION OF ARGINASE PRODUCTION IN MOUSE PERITONEAL MACROPHAGES

JAKWAY, JAMES PATRICK

1980

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Mycoplasma contamination: a hazard of screening hybridoma supernatants for inhibition of [ 3H]thymidine incorporation

Journal of immunological methods, 1984-03, Vol.67 (2), p.337-345

1984

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Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist

Discovery of 2-Hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist

Minimum significant ratio of selectivity ratios (MSRSR) and confidence in ratio of selectivity ratios (CRSR): quantitative measures for selectivity ratios obtained by screening assays

3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists

The synthesis of substituted bipiperidine amide compounds as CCR3 antagonists

Identification of full, partial and inverse CC chemokine receptor 3 agonists using [ 35S]GTPγS binding

Receptor reserve analysis of the human CCR3 receptor in eosinophils and CCR3-transfected cells

Pertussis Toxin Inhibition of B Cell and Macrophage Responses to Bacterial Lipopolysaccharide

Identification of Differentially Expressed Genes in a Monkey Model of Allergic Asthma by Microarray Technology

Effects of Cyclosporin A and Dinactin on T-Cell Proliferation, Interleukin-5 Production, and Murine Pulmonary Inflammation

C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists

Synthesis and structure–activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists

The synthesis of substituted bipiperidine amide compounds as CCR3 ligands: Antagonists versus agonists

Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding

Postjunctional α2C-adrenoceptor contractility in human saphenous vein

B-Lymphocyte Signal Transduction in Response to Anti-Immunoglobulin and Bacterial Lipopolysaccharide

Postjunctional α 2C-adrenoceptor contractility in human saphenous vein

Cytokine Inhibition by A Novel Steroid, Mometasone Furoate

Pertussis toxin inhibition of B cell and macrophage response to bacterial lipopolysaccharide

Synthesis of dibenzo[a,d]cycloheptanes as cytokine biosynthesis inhibitors

[45] The hazards of mycoplasma contamination in the screening of hybridoma supernatants for effects on [ 3H]thymidine incorporation

Suppression of in vitro cytotoxic response by macrophages due to induced arginase

Stimulation of T-cell activation by UV-treated, antigen-pulsed macrophages: Evidence for a requirement for antigen processing and interleukin 1 secretion

SERUM FACTORS REQUIRED FOR THE IN VITRO INDUCTION OF ARGINASE PRODUCTION IN MOUSE PERITONEAL MACROPHAGES

Mycoplasma contamination: a hazard of screening hybridoma supernatants for inhibition of [ 3H]thymidine incorporation

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