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Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis

Chemical reviews, 2011-10, Vol.111 (10), p.5821-5865

2011

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Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis

Journal of internal medicine, 2022-11, Vol.292 (5), p.745-763

2022

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A review on mPGES-1 inhibitors: From preclinical studies to clinical applications

Prostaglandins & other lipid mediators, 2020-04, Vol.147, p.106383, Article 106383

2020

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Membrane prostaglandin E synthase-1: a novel therapeutic target

Pharmacological reviews, 2007-09, Vol.59 (3), p.207-224

2007

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Anti–Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis

Arthritis & rheumatology (Hoboken, N.J.), 2020-10, Vol.72 (10), p.1658-1667

2020

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Proinflammatory Histidyl–Transfer RNA Synthetase–Specific CD4+ T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies

Arthritis & rheumatology (Hoboken, N.J.), 2020-01, Vol.72 (1), p.179-191

2020

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Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis

Arthritis & rheumatology (Hoboken, N.J.), 2013-04, Vol.65 (4), p.899-910

2013

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Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

The Journal of clinical investigation, 2012-05, Vol.122 (5), p.1791-1802

2012

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Effects of microsomal prostaglandin E synthase‐1 inhibition on resistance artery tone in patients with end stage kidney disease

British journal of pharmacology, 2022-04, Vol.179 (7), p.1433-1449

2022

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High‐content screening of drug combinations of an mPGES‐1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance

Molecular oncology, 2024-02, Vol.18 (2), p.317-335

2024

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Microsomal prostaglandin E synthase‐1 inhibition prevents adverse cardiac remodelling after myocardial infarction in mice

British journal of pharmacology, 2023-08, Vol.180 (15), p.1981-1998

2023

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Presence of autoantibodies in "seronegative" rheumatoid arthritis associates with classical risk factors and high disease activity

Arthritis research & therapy, 2020-07, Vol.22 (1), p.170-11, Article 170

2020

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Inhibition of microsomal PGE synthase‐1 reduces human vascular tone by increasing PGI2: a safer alternative to COX‐2 inhibition

British journal of pharmacology, 2017-11, Vol.174 (22), p.4087-4098

2017

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Persisting eicosanoid pathways in rheumatic diseases

Nature reviews. Rheumatology, 2014-04, Vol.10 (4), p.229-241

2014

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Helminthic dehydrogenase drives PGE2 and IL‐10 production in monocytes to potentiate Treg induction

EMBO reports, 2022-05, Vol.23 (5), p.e54096-n/a

2022

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Characterization of Microsomal Prostaglandin E Synthase 1 Inhibitors

Basic & clinical pharmacology & toxicology, 2014-01, Vol.114 (1), p.64-69

2014

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COX/mPGES-1/PGE₂ pathway depicts an inflammatory-dependent high-risk neuroblastoma subset

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (26), p.8070-8075

2015

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Prostaglandin E2 Exerts Multiple Regulatory Actions on Human Obese Adipose Tissue Remodeling, Inflammation, Adaptive Thermogenesis and Lipolysis

PloS one, 2016-04, Vol.11 (4), p.e0153751-e0153751

2016

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In early rheumatoid arthritis, anticitrullinated peptide antibodies associate with low number of affected joints and rheumatoid factor associates with systemic inflammation

Annals of the rheumatic diseases, 2024-03, Vol.83 (3), p.277-287

2024

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Establishment of an in vitro 3D model for neuroblastoma enables preclinical investigation of combined tumor‐stroma drug targeting

The FASEB journal, 2020-08, Vol.34 (8), p.11101-11114

2020

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MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (25), p.10258-10263

2013

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Biological characterization of new inhibitors of microsomal PGE synthase‐1 in preclinical models of inflammation and vascular tone

British journal of pharmacology, 2019-12, Vol.176 (24), p.4625-4638

2019

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Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

Annals of the rheumatic diseases, 2015-02, Vol.74 (2), p.375-380

2015

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The anti-inflammatory and vasoprotective properties of mPGES-1 inhibition offer promising therapeutic potential

Expert opinion on therapeutic targets, 2023-11, Vol.27 (11), p.1115-1123

2023

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Phosphodiesterase 4A confers resistance to PGE2‐mediated suppression in CD25+/CD54+ NK cells

EMBO reports, 2021-03, Vol.22 (3), p.e51329-n/a

2021

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Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis

Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis

A review on mPGES-1 inhibitors: From preclinical studies to clinical applications

Membrane prostaglandin E synthase-1: a novel therapeutic target

Anti–Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis

Proinflammatory Histidyl–Transfer RNA Synthetase–Specific CD4+ T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies

Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

Effects of microsomal prostaglandin E synthase‐1 inhibition on resistance artery tone in patients with end stage kidney disease

High‐content screening of drug combinations of an mPGES‐1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance

Microsomal prostaglandin E synthase‐1 inhibition prevents adverse cardiac remodelling after myocardial infarction in mice

Presence of autoantibodies in "seronegative" rheumatoid arthritis associates with classical risk factors and high disease activity

Inhibition of microsomal PGE synthase‐1 reduces human vascular tone by increasing PGI2: a safer alternative to COX‐2 inhibition

Persisting eicosanoid pathways in rheumatic diseases

Helminthic dehydrogenase drives PGE2 and IL‐10 production in monocytes to potentiate Treg induction

Characterization of Microsomal Prostaglandin E Synthase 1 Inhibitors

COX/mPGES-1/PGE₂ pathway depicts an inflammatory-dependent high-risk neuroblastoma subset

Prostaglandin E2 Exerts Multiple Regulatory Actions on Human Obese Adipose Tissue Remodeling, Inflammation, Adaptive Thermogenesis and Lipolysis

In early rheumatoid arthritis, anticitrullinated peptide antibodies associate with low number of affected joints and rheumatoid factor associates with systemic inflammation

Establishment of an in vitro 3D model for neuroblastoma enables preclinical investigation of combined tumor‐stroma drug targeting

MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

Biological characterization of new inhibitors of microsomal PGE synthase‐1 in preclinical models of inflammation and vascular tone

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

The anti-inflammatory and vasoprotective properties of mPGES-1 inhibition offer promising therapeutic potential

Phosphodiesterase 4A confers resistance to PGE2‐mediated suppression in CD25+/CD54+ NK cells

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