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Mineralocorticoid receptor antagonists and kidney diseases: pathophysiological basis

Kidney international, 2019-08, Vol.96 (2), p.302-319

2019

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Mineralocorticoid receptor antagonists in diabetic kidney disease - mechanistic and therapeutic effects

Nature reviews. Nephrology, 2022-01, Vol.18 (1), p.56-70

2022

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Roles of Mineralocorticoid Receptors in Cardiovascular and Cardiorenal Diseases

Annual review of physiology, 2022-02, Vol.84, p.585

2022

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Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy

The Journal of clinical investigation, 2012-07, Vol.122 (7), p.2672-2679

2012

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Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1

Journal of the American Society of Nephrology, 2017-04, Vol.28 (4), p.1216-1226

2017

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Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction

Hypertension (Dallas, Tex. 1979), 2016-04, Vol.67 (4), p.717-723

2016

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Cutaneous Wound Healing in Diabetic Mice Is Improved by Topical Mineralocorticoid Receptor Blockade

Journal of investigative dermatology, 2020-01, Vol.140 (1), p.223-234.e7

2020

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Steroidal and Novel Non-steroidal Mineralocorticoid Receptor Antagonists in Heart Failure and Cardiorenal Diseases: Comparison at Bench and Bedside

Handbook of experimental pharmacology, 2017-01, Vol.243, p.271-305

2017

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Differentiation between emerging non-steroidal and established steroidal mineralocorticoid receptor antagonists: head-to-head comparisons of pharmacological and clinical characteristics

Expert opinion on investigational drugs, 2021-11, Vol.30 (11), p.1141-1157

2021

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Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration

Nature communications, 2019-01, Vol.10 (1), p.369-369, Article 369

2019

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Galectin-3 Blockade Inhibits Cardiac Inflammation and Fibrosis in Experimental Hyperaldosteronism and Hypertension

Hypertension (Dallas, Tex. 1979), 2015-10, Vol.66 (4), p.767-775

2015

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Epithelial Sodium Channel in Aldosterone-Induced Endothelium Stiffness and Aortic Dysfunction

Hypertension (Dallas, Tex. 1979), 2018-09, Vol.72 (3), p.731-738

2018

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Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion

PloS one, 2018-02, Vol.13 (2), p.e0193380

2018

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Pathophysiologic mechanisms in diabetic kidney disease: A focus on current and future therapeutic targets

Diabetes, obesity & metabolism, 2020-04, Vol.22 (S1), p.16-31

2020

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CT-1 (Cardiotrophin-1)-Gal-3 (Galectin-3) Axis in Cardiac Fibrosis and Inflammation: Mechanistic Insights and Clinical Implications

Hypertension (Dallas, Tex. 1979), 2019-03, Vol.73 (3), p.602-611

2019

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Mineralocorticoid receptor activation and blockade: an emerging paradigm in chronic kidney disease

Kidney international, 2011-05, Vol.79 (10), p.1051-1060

2011

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Rapid glycemic regulation in poorly controlled patients living with diabetes, a new associated factor in the pathophysiology of Charcot's acute neuroarthropathy

PloS one, 2020-05, Vol.15 (5), p.e0233168-e0233168

2020

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Nonepithelial mineralocorticoid receptor activation as a determinant of kidney disease

Kidney international supplements, 2022-04, Vol.12 (1), p.12-18

2022

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Mineralocorticoid Receptor Activation and Mineralocorticoid Receptor Antagonist Treatment in Cardiac and Renal Diseases

Hypertension (Dallas, Tex. 1979), 2015-02, Vol.65 (2), p.257-263

2015

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Endothelial Mineralocorticoid Receptors Differentially Contribute to Coronary and Mesenteric Vascular Function Without Modulating Blood Pressure

Hypertension (Dallas, Tex. 1979), 2015-11, Vol.66 (5), p.988-997

2015

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Epithelial Sodium Channel Stiffens the Vascular Endothelium In Vitro and in Liddle Mice

Hypertension (Dallas, Tex. 1979), 2013-05, Vol.61 (5), p.1053-1059

2013

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Epithelial sodium channels in endothelial cells mediate diet-induced endothelium stiffness and impaired vascular relaxation in obese female mice

Metabolism, clinical and experimental, 2019-10, Vol.99, p.57-66

2019

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Mineralocorticoid Receptor and Cardiovascular Disease

American journal of hypertension, 2018-10, Vol.31 (11), p.1165-1174

2018

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Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

European heart journal, 2014-04, Vol.35 (14), p.932-941

2014

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Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis

Progress in retinal and eye research, 2015-09, Vol.48, p.82-118

2015

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Mineralocorticoid receptor antagonists and kidney diseases: pathophysiological basis

Mineralocorticoid receptor antagonists in diabetic kidney disease - mechanistic and therapeutic effects

Roles of Mineralocorticoid Receptors in Cardiovascular and Cardiorenal Diseases

Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy

Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1

Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction

Cutaneous Wound Healing in Diabetic Mice Is Improved by Topical Mineralocorticoid Receptor Blockade

Steroidal and Novel Non-steroidal Mineralocorticoid Receptor Antagonists in Heart Failure and Cardiorenal Diseases: Comparison at Bench and Bedside

Differentiation between emerging non-steroidal and established steroidal mineralocorticoid receptor antagonists: head-to-head comparisons of pharmacological and clinical characteristics

Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration

Galectin-3 Blockade Inhibits Cardiac Inflammation and Fibrosis in Experimental Hyperaldosteronism and Hypertension

Epithelial Sodium Channel in Aldosterone-Induced Endothelium Stiffness and Aortic Dysfunction

Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion

Pathophysiologic mechanisms in diabetic kidney disease: A focus on current and future therapeutic targets

CT-1 (Cardiotrophin-1)-Gal-3 (Galectin-3) Axis in Cardiac Fibrosis and Inflammation: Mechanistic Insights and Clinical Implications

Mineralocorticoid receptor activation and blockade: an emerging paradigm in chronic kidney disease

Rapid glycemic regulation in poorly controlled patients living with diabetes, a new associated factor in the pathophysiology of Charcot's acute neuroarthropathy

Nonepithelial mineralocorticoid receptor activation as a determinant of kidney disease

Mineralocorticoid Receptor Activation and Mineralocorticoid Receptor Antagonist Treatment in Cardiac and Renal Diseases

Endothelial Mineralocorticoid Receptors Differentially Contribute to Coronary and Mesenteric Vascular Function Without Modulating Blood Pressure

Epithelial Sodium Channel Stiffens the Vascular Endothelium In Vitro and in Liddle Mice

Epithelial sodium channels in endothelial cells mediate diet-induced endothelium stiffness and impaired vascular relaxation in obese female mice

Mineralocorticoid Receptor and Cardiovascular Disease

Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis

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