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Development and application of an enantioselective liquid chromatography – tandem mass spectrometry method for the quantification of enantiomers to evaluate in vivo chiral inversion in beagle dog

Journal of Chromatography Open, 2023-11, Vol.3, p.100077, Article 100077

2023

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Direct determination of unbound intrinsic drug clearance in the microsomal stability assay

Drug metabolism and disposition, 2005-09, Vol.33 (9), p.1319-1324

2005

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Development of carboxylic acid replacements in indole- N-acetamide inhibitors of hepatitis C virus NS5B polymerase

Bioorganic & medicinal chemistry letters, 2007-09, Vol.17 (18), p.5143-5149

2007

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Development and validation of a liquid chromatography-triple quadrupole mass spectrometry method for the determination of isopeptide ε-(γ-glutamyl) lysine in human urine as biomarker for transglutaminase 2 cross-linked proteins

Journal of Chromatography A, 2023-06, Vol.1699, p.464002, Article 464002

2023

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IQ consortium perspective: complementary LBA and LC–MS in protein therapeutics bioanalysis and biotransformation assessment

Bioanalysis, 2020-02, Vol.12 (4), p.257-270

2020

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Introduction of a routine quan/qual approach into research DMPK: experiences and evolving strategies

Bioanalysis, 2014-01, Vol.6 (24), p.3337-3348

2014

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Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6705-6723

2018

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Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

mAbs, 2016-10, Vol.8 (7), p.1336-1346

2016

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Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

mAbs, 2016-10, Vol.8 (7), p.1319-1335

2016

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Design, synthesis and biological evaluation of peptide derivatives of l-dopa as anti-parkinsonian agents

Bioorganic & medicinal chemistry letters, 2013-10, Vol.23 (19), p.5279-5282

2013

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Design, synthesis and biological evaluation of l-dopa amide derivatives as potential prodrugs for the treatment of Parkinson’s disease

European journal of medicinal chemistry, 2010-09, Vol.45 (9), p.4035-4042

2010

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Benserazide dosing regimen affects the response to L-3,4-dihydroxyphenylalanine in the 6-hydroxydopamine-lesioned rat

Behavioural pharmacology, 2012-04, Vol.23 (2), p.126-133

2012

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The toxicity of opiates and their metabolites in HepG2 cells

Chemico-biological interactions, 2003-10, Vol.146 (2), p.121-129

2003

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Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

mAbs, 2016, Vol.8 (7), p.1336-1346

2016

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High-Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies

LC GC Europe, 2004, Vol.17 (2), p.114

Jairaj, Mark

2004

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Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

mAbs, 2016, Vol.8 (7), p.1319-1335

2016

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Dynamic Heterochromatin States in Anisotropic Nuclei of Cells on Aligned Nanofibers

ACS nano, 2022-07, Vol.16 (7), p.10754-10767

2022

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A randomized trial of once-daily fluticasone furoate/vilanterol or vilanterol versus placebo to determine effects on arterial stiffness in COPD

International journal of chronic obstructive pulmonary disease, 2017-01, Vol.12, p.351-365

2017

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Immunosurveillance and Survivin-Specific T-Cell Immunity in Children With High-Risk Neuroblastoma

Journal of clinical oncology, 2006-12, Vol.24 (36), p.5725-5734

2006

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Bankruptcy and Financial Distress in US Small and Medium Sized Enterprises

SSRN Electronic Journal

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Development and application of an enantioselective liquid chromatography – tandem mass spectrometry method for the quantification of enantiomers to evaluate in vivo chiral inversion in beagle dog

Direct determination of unbound intrinsic drug clearance in the microsomal stability assay

A Mixture of Functionally Oligoclonal Humanized Monoclonal Antibodies That Neutralize Clostridium difficile TcdA and TcdB with High Levels of In Vitro Potency Shows In Vivo Protection in a Hamster Infection Model

Development of carboxylic acid replacements in indole- N-acetamide inhibitors of hepatitis C virus NS5B polymerase

Development and validation of a liquid chromatography-triple quadrupole mass spectrometry method for the determination of isopeptide ε-(γ-glutamyl) lysine in human urine as biomarker for transglutaminase 2 cross-linked proteins

IQ consortium perspective: complementary LBA and LC–MS in protein therapeutics bioanalysis and biotransformation assessment

Introduction of a routine quan/qual approach into research DMPK: experiences and evolving strategies

Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

Design, synthesis and biological evaluation of peptide derivatives of l-dopa as anti-parkinsonian agents

Design, synthesis and biological evaluation of l-dopa amide derivatives as potential prodrugs for the treatment of Parkinson’s disease

Benserazide dosing regimen affects the response to L-3,4-dihydroxyphenylalanine in the 6-hydroxydopamine-lesioned rat

The toxicity of opiates and their metabolites in HepG2 cells

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

High-Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies

Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

Dynamic Heterochromatin States in Anisotropic Nuclei of Cells on Aligned Nanofibers

A randomized trial of once-daily fluticasone furoate/vilanterol or vilanterol versus placebo to determine effects on arterial stiffness in COPD

Immunosurveillance and Survivin-Specific T-Cell Immunity in Children With High-Risk Neuroblastoma

Bankruptcy and Financial Distress in US Small and Medium Sized Enterprises

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