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An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol

Frontiers in pharmacology, 2017-06, Vol.8, p.422-422

2017

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Antitumor Cannabinoid Chemotypes: Structural Insights

Frontiers in pharmacology, 2019-05, Vol.10, p.621

2019

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Advances Towards The Discovery of GPR55 Ligands

Current medicinal chemistry, 2016-01, Vol.23 (20), p.2087-2100

2016

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Relevance of Peroxisome Proliferator Activated Receptors in Multitarget Paradigm Associated with the Endocannabinoid System

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1001

2021

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Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update

Expert opinion on therapeutic patents, 2016-07, Vol.26 (7), p.843-856

2016

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Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders

Frontiers in neuroscience, 2016-09, Vol.10, p.406-406

2016

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Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling

Pharmacological research, 2024-10, Vol.208, p.107363, Article 107363

2024

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The Binding Mode to Orthosteric Sites and/or Exosites Underlies the Therapeutic Potential of Drugs Targeting Cannabinoid CB2 Receptors

Frontiers in pharmacology, 2022-02, Vol.13, p.852631-852631

2022

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Allosteric Modulators of the CB1 Cannabinoid Receptor: A Structural Update Review

Cannabis and cannabinoid research, 2016-01, Vol.1 (1), p.22-30

2016

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Palmitoleoylethanolamide Is an Efficient Anti-Obesity Endogenous Compound: Comparison with Oleylethanolamide in Diet-Induced Obesity

Nutrients, 2021-07, Vol.13 (8), p.2589

2021

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Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis

Molecules (Basel, Switzerland), 2021-12, Vol.26 (24), p.7643

2021

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Administration of Linoleoylethanolamide Reduced Weight Gain, Dyslipidemia, and Inflammation Associated with High-Fat-Diet-Induced Obesity

Nutrients, 2023-10, Vol.15 (20), p.4448

2023

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Targeting CB2 and TRPV1: Computational Approaches for the Identification of Dual Modulators

Frontiers in molecular biosciences, 2022-02, Vol.9, p.841190

2022

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CB1 cannabinoid antagonists: structure-activity relationships and potential therapeutic applications

Current topics in medicinal chemistry, 2008-02, Vol.8 (3), p.205-230

2008

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Novel approaches and current challenges with targeting the endocannabinoid system

Expert opinion on drug discovery, 2020-08, Vol.15 (8), p.917-930

2020

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New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking

European journal of medicinal chemistry, 2017-02, Vol.127, p.398-412

2017

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Synthetic and Natural Derivatives of Cannabidiol

Advances in experimental medicine and biology, 2021-01, Vol.1297, p.11-25

2021

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Identification of Novel GPR55 Modulators Using Cell-Impedance-Based Label-Free Technology

Journal of medicinal chemistry, 2016-03, Vol.59 (5), p.1840-1853

2016

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Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism

PloS one, 2013-04, Vol.8 (4), p.e60918-e60918

2013

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Emerging strategies targeting CB2 cannabinoid receptor: Biased agonism and allosterism

Biochemical pharmacology, 2018-11, Vol.157, p.8-17

2018

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Dynamic NMR Study of the Mechanisms of Double, Triple, and Quadruple Proton and Deuteron Transfer in Cyclic Hydrogen Bonded Solids of Pyrazole Derivatives

Journal of the American Chemical Society, 2004-09, Vol.126 (37), p.11718-11732

2004

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Antiprotozoal Activity of 1-Phenethyl-4-Aminopiperidine Derivatives

Antimicrobial Agents and Chemotherapy, 2009-09, Vol.53 (9), p.3815-3821

2009

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Preparation of 2,2-dimethylchroman-4-ones from 5-alkyl-substituted resorcinols: microwave-assisted synthesis and theoretical calculations

ARKIVOC, 2013-11, Vol.2014 (2), p.319-332

2013

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N-substituted-1,2,3-triazoles: synthesis, characterization and evaluation as cannabinoid ligands

ARKIVOC, 2010-05, Vol.2010 (2), p.127-147

2010

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Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes

Biochemical pharmacology, 2018-11, Vol.157, p.148-158

2018

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An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol

Antitumor Cannabinoid Chemotypes: Structural Insights

Advances Towards The Discovery of GPR55 Ligands

Relevance of Peroxisome Proliferator Activated Receptors in Multitarget Paradigm Associated with the Endocannabinoid System

Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update

Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders

Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling

The Binding Mode to Orthosteric Sites and/or Exosites Underlies the Therapeutic Potential of Drugs Targeting Cannabinoid CB2 Receptors

Allosteric Modulators of the CB1 Cannabinoid Receptor: A Structural Update Review

Palmitoleoylethanolamide Is an Efficient Anti-Obesity Endogenous Compound: Comparison with Oleylethanolamide in Diet-Induced Obesity

Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis

Administration of Linoleoylethanolamide Reduced Weight Gain, Dyslipidemia, and Inflammation Associated with High-Fat-Diet-Induced Obesity

Targeting CB2 and TRPV1: Computational Approaches for the Identification of Dual Modulators

CB1 cannabinoid antagonists: structure-activity relationships and potential therapeutic applications

Novel approaches and current challenges with targeting the endocannabinoid system

New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking

Synthetic and Natural Derivatives of Cannabidiol

Identification of Novel GPR55 Modulators Using Cell-Impedance-Based Label-Free Technology

Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism

Emerging strategies targeting CB2 cannabinoid receptor: Biased agonism and allosterism

Dynamic NMR Study of the Mechanisms of Double, Triple, and Quadruple Proton and Deuteron Transfer in Cyclic Hydrogen Bonded Solids of Pyrazole Derivatives

Antiprotozoal Activity of 1-Phenethyl-4-Aminopiperidine Derivatives

Preparation of 2,2-dimethylchroman-4-ones from 5-alkyl-substituted resorcinols: microwave-assisted synthesis and theoretical calculations

N-substituted-1,2,3-triazoles: synthesis, characterization and evaluation as cannabinoid ligands

Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes

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