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Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy

eLife, 2019-01, Vol.8

2019

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A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy

eLife, 2015-01, Vol.4

2015

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NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins

eLife, 2018-03, Vol.7

2018

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The evolution of DUX4 gene regulation and its implication for facioscapulohumeral muscular dystrophy

Biochimica et biophysica acta. Molecular basis of disease, 2022-05, Vol.1868 (5), p.166367-166367, Article 166367

Jagannathan, Sujatha

2022

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DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy

PLoS genetics, 2017-03, Vol.13 (3), p.e1006658-e1006658

2017

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The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

PLoS biology, 2023-09, Vol.21 (9), p.e3002317-e3002317

2023

Volltextzugriff (PDF)

Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression

Cell reports (Cambridge), 2023-06, Vol.42 (6), p.112642-112642, Article 112642

2023

Volltextzugriff (PDF)

Multifunctional Roles for the Protein Translocation Machinery in RNA Anchoring to the Endoplasmic Reticulum

The Journal of biological chemistry, 2014-09, Vol.289 (37), p.25907-25924

2014

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Analyzing mRNA localization to the endoplasmic reticulum via cell fractionation

Methods in molecular biology (Clifton, N.J.), 2011, Vol.714, p.301

2011

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Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells

Molecular biology of the cell, 2011-07, Vol.22 (14), p.2646-2658

2011

Volltextzugriff (PDF)

Meeting report: the 2021 FSHD International Research Congress

Skeletal muscle, 2022-01, Vol.12 (1), p.1-1, Article 1

2022

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Premature translational termination products are rapidly degraded substrates for MHC class I presentation

PloS one, 2012-12, Vol.7 (12), p.e51968

2012

Volltextzugriff (PDF)

The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity

Molecular cell, 2017-07, Vol.67 (2), p.239-251.e6

2017

Volltextzugriff (PDF)

How to get away with nonsense: Mechanisms and consequences of escape from nonsense‐mediated RNA decay

Wiley interdisciplinary reviews. RNA, 2020-01, Vol.11 (1), p.e1560-n/a

2020

Volltextzugriff (PDF)

A system of reporters for comparative investigation of EJC-independent and EJC-enhanced nonsense-mediated mRNA decay

Nucleic acids research, 2024-04, Vol.52 (6), p.e34

2024

Volltextzugriff (PDF)

Slow Down to Catch Up

Cell, 2019-08, Vol.178 (4), p.774-776

2019

Volltextzugriff (PDF)

Recruitment of endoplasmic reticulum-targeted and cytosolic mRNAs into membrane-associated stress granules

RNA (Cambridge), 2021-10, Vol.27 (10), p.1241-1256

2021

Volltextzugriff (PDF)

Principles, mechanisms, and biological implications of translation termination-reinitiation

RNA (Cambridge), 2023-07, Vol.29 (7), p.865-884

2023

Volltextzugriff (PDF)

Congenital myotonic dystrophy-an RNA-mediated disease across a developmental continuum

Genes & development, 2017-06, Vol.31 (11), p.1067-1068

2017

Volltextzugriff (PDF)

Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells

Human molecular genetics, 2016-10, Vol.25 (20), p.4419-4431

2016

Volltextzugriff (PDF)

De novo translation initiation on membrane-bound ribosomes as a mechanism for localization of cytosolic protein mRNAs to the endoplasmic reticulum

RNA (Cambridge), 2014-10, Vol.20 (10), p.1489-1498

2014

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A Targeted Approach for Evaluating DUX4-Regulated Proteins as Potential Serum Biomarkers for Facioscapulohumeral Muscular Dystrophy Using Immunoassay Proteomics

Journal of neuromuscular diseases, 2023-01, Vol.10 (6), p.1031-1040

2023

Volltextzugriff (PDF)

Bimodal mechanism of mRNA association with the endoplasmic reticulum (ER)

The FASEB journal, 2011-04, Vol.25 (S1), p.lb51-lb51

2011

Volltextzugriff (PDF)

Post-transcriptional Regulation of Membrane-associated RNAs

Jagannathan, Sujatha

2013

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Moving Vehicle Detection and Classification Using Gaussian Mixture Model and Ensemble Deep Learning Technique

Wireless communications and mobile computing, 2021, Vol.2021 (1)

2021

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Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy

A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy

NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins

The evolution of DUX4 gene regulation and its implication for facioscapulohumeral muscular dystrophy

DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy

The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression

Multifunctional Roles for the Protein Translocation Machinery in RNA Anchoring to the Endoplasmic Reticulum

Analyzing mRNA localization to the endoplasmic reticulum via cell fractionation

Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells

Meeting report: the 2021 FSHD International Research Congress

Premature translational termination products are rapidly degraded substrates for MHC class I presentation

The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity

How to get away with nonsense: Mechanisms and consequences of escape from nonsense‐mediated RNA decay

A system of reporters for comparative investigation of EJC-independent and EJC-enhanced nonsense-mediated mRNA decay

Slow Down to Catch Up

Recruitment of endoplasmic reticulum-targeted and cytosolic mRNAs into membrane-associated stress granules

Principles, mechanisms, and biological implications of translation termination-reinitiation

Congenital myotonic dystrophy-an RNA-mediated disease across a developmental continuum

Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells

De novo translation initiation on membrane-bound ribosomes as a mechanism for localization of cytosolic protein mRNAs to the endoplasmic reticulum

A Targeted Approach for Evaluating DUX4-Regulated Proteins as Potential Serum Biomarkers for Facioscapulohumeral Muscular Dystrophy Using Immunoassay Proteomics

Bimodal mechanism of mRNA association with the endoplasmic reticulum (ER)

Post-transcriptional Regulation of Membrane-associated RNAs

Moving Vehicle Detection and Classification Using Gaussian Mixture Model and Ensemble Deep Learning Technique

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