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Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (43), p.11506-11511

2017

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Evidence for Multiple Recent Host Species Shifts among the Ranaviruses (Family Iridoviridae)

Journal of Virology, 2010-03, Vol.84 (6), p.2636-2647

2010

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Convergent Loss of the Necroptosis Pathway in Disparate Mammalian Lineages Shapes Viruses Countermeasures

Frontiers in immunology, 2021-09, Vol.12, p.747737-747737

2021

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The Amino Terminus of the Vaccinia Virus E3 Protein Is Necessary To Inhibit the Interferon Response

Journal of Virology, 2012-05, Vol.86 (10), p.5895-5904

2012

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Innate Immune Evasion Mediated by the Ambystoma tigrinum Virus Eukaryotic Translation Initiation Factor 2α Homologue

Journal of Virology, 2011-05, Vol.85 (10), p.5061-5069

2011

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Small Hero with Great Powers: Vaccinia Virus E3 Protein and Evasion of the Type I IFN Response

Biomedicines, 2022-01, Vol.10 (2), p.235

2022

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Loss of Protein Kinase PKR Expression in Human HeLa Cells Complements the Vaccinia Virus E3L Deletion Mutant Phenotype by Restoration of Viral Protein Synthesis

Journal of Virology, 2008-01, Vol.82 (2), p.840-848

2008

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Improved NYVAC-based vaccine vectors

PloS one, 2011-11, Vol.6 (11), p.e25674-e25674

2011

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Mouse Hepatitis Coronavirus A59 Nucleocapsid Protein Is a Type I Interferon Antagonist

Journal of Virology, 2007-03, Vol.81 (6), p.2554-2563

2007

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Regulation of inflammatory gene expression in PBMCs by immunostimulatory botanicals

PloS one, 2010-09, Vol.5 (9), p.e12561

2010

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Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis

Cell host & microbe, 2021-08, Vol.29 (8), p.1266-1276.e5

2021

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Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501YMA30 Strain of SARS-CoV-2

Vaccines (Basel), 2022-07, Vol.10 (8), p.1172

2022

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A Role for Z-DNA Binding in Vaccinia Virus Pathogenesis

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (12), p.6974-6979

2003

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Protein Kinase PKR-Dependent Activation of Mitogen-Activated Protein Kinases Occurs through Mitochondrial Adapter IPS-1 and Is Antagonized by Vaccinia Virus E3L

Journal of Virology, 2009-06, Vol.83 (11), p.5718-5725

2009

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Type I Interferon: Monkeypox/Mpox Viruses Achilles Heel?

Advances in experimental medicine and biology, 2024, Vol.1451, p.125

2024

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In vitro characterization of a nineteenth-century therapy for smallpox

PloS one, 2012-03, Vol.7 (3), p.e32610-e32610

2012

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Detecting Necroptosis in Virus-Infected Cells

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2225, p.199

2021

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Use of a recombinant vaccinia virus expressing interferon gamma for post-exposure protection against vaccinia and ectromelia viruses

PloS one, 2013-10, Vol.8 (10), p.e77879-e77879

2013

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Attenuated NYCBH vaccinia virus deleted for the E3L gene confers partial protection against lethal monkeypox virus disease in cynomolgus macaques

Vaccine, 2011-12, Vol.29 (52), p.9684-9690

2011

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Canonical cellular stress granules are required for arsenite-induced necroptosis mediated by Z-DNA-binding protein 1

Science signaling, 2023-03, Vol.16 (776), p.eabq0837

2023

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Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

Journal of Virology, 2002-09, Vol.76 (18), p.9207-9217

2002

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Suppression of Proinflammatory Signal Transduction and Gene Expression by the Dual Nucleic Acid Binding Domains of the Vaccinia Virus E3L Proteins

Journal of Virology, 2006-10, Vol.80 (20), p.10083-10095

2006

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Use of a negative selectable marker for rapid selection of recombinant vaccinia virus

BioTechniques, 2011-05, Vol.50 (5), p.303-309

2011

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Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3

Evidence for Multiple Recent Host Species Shifts among the Ranaviruses (Family Iridoviridae)

Convergent Loss of the Necroptosis Pathway in Disparate Mammalian Lineages Shapes Viruses Countermeasures

The Amino Terminus of the Vaccinia Virus E3 Protein Is Necessary To Inhibit the Interferon Response

Innate Immune Evasion Mediated by the Ambystoma tigrinum Virus Eukaryotic Translation Initiation Factor 2α Homologue

Small Hero with Great Powers: Vaccinia Virus E3 Protein and Evasion of the Type I IFN Response

Loss of Protein Kinase PKR Expression in Human HeLa Cells Complements the Vaccinia Virus E3L Deletion Mutant Phenotype by Restoration of Viral Protein Synthesis

Improved NYVAC-based vaccine vectors

Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques

Mouse Hepatitis Coronavirus A59 Nucleocapsid Protein Is a Type I Interferon Antagonist

Regulation of inflammatory gene expression in PBMCs by immunostimulatory botanicals

Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis

Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501YMA30 Strain of SARS-CoV-2

A Role for Z-DNA Binding in Vaccinia Virus Pathogenesis

Protein Kinase PKR-Dependent Activation of Mitogen-Activated Protein Kinases Occurs through Mitochondrial Adapter IPS-1 and Is Antagonized by Vaccinia Virus E3L

Type I Interferon: Monkeypox/Mpox Viruses Achilles Heel?

In vitro characterization of a nineteenth-century therapy for smallpox

Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors

Detecting Necroptosis in Virus-Infected Cells

Use of a recombinant vaccinia virus expressing interferon gamma for post-exposure protection against vaccinia and ectromelia viruses

Attenuated NYCBH vaccinia virus deleted for the E3L gene confers partial protection against lethal monkeypox virus disease in cynomolgus macaques

Canonical cellular stress granules are required for arsenite-induced necroptosis mediated by Z-DNA-binding protein 1

Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

Suppression of Proinflammatory Signal Transduction and Gene Expression by the Dual Nucleic Acid Binding Domains of the Vaccinia Virus E3L Proteins

Use of a negative selectable marker for rapid selection of recombinant vaccinia virus

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