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STATs in cancer inflammation and immunity: a leading role for STAT3

Nature reviews. Cancer, 2009-11, Vol.9 (11), p.798-809

2009

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The STATs of cancer - new molecular targets come of age

Nature reviews. Cancer, 2004-02, Vol.4 (2), p.97-105

2004

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Differences and similarities between cancer and somatic stem cells: therapeutic implications

Stem cell research & therapy, 2020-11, Vol.11 (1), p.489-489, Article 489

2020

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STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors

Nature medicine, 2010-12, Vol.16 (12), p.1421-1428

2010

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miR‐194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice

Hepatology (Baltimore, Md.), 2010-12, Vol.52 (6), p.2148-2157

2010

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Activated STAT Signaling in Human Tumors Provides Novel Molecular Targets for Therapeutic Intervention

Clinical cancer research, 2002-04, Vol.8 (4), p.945-954

2002

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The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Cancer cell, 2009-12, Vol.16 (6), p.487-497

2009

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Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (20), p.7765-7769

2012

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S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites

Cancer cell, 2012-05, Vol.21 (5), p.642-654

2012

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Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (18), p.7391-7396

2007

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Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

Nature medicine, 2005-12, Vol.11 (12), p.1314-1321

2005

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Critical Role of STAT3 in IL-6―Mediated Drug Resistance in Human Neuroblastoma

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (13), p.3852-3864

2013

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Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (32), p.13079-13084

2013

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Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells

Blood, 2014-05, Vol.123 (18), p.2826-2837

2014

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

Nature medicine, 2004-01, Vol.10 (1), p.48-54

2004

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SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells

Molecular cancer therapeutics, 2008-05, Vol.7 (5), p.1185-1194

2008

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Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer

Molecular cancer, 2015-05, Vol.14 (1), p.100-100, Article 100

2015

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Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways

Oncogene, 2005-08, Vol.24 (36), p.5552-5560

2005

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General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors: Enantioselective Total Syntheses of (+)- and (−)-Gliocladine C, (+)-Leptosin D, (+)-T988C, (+)-Bionectin A, and (+)-Gliocladin A

Journal of the American Chemical Society, 2013-03, Vol.135 (10), p.4117-4128

2013

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Inhibition of Src Family Kinases with Dasatinib Blocks Migration and Invasion of Human Melanoma Cells

Molecular cancer research, 2008-11, Vol.6 (11), p.1766-1774

2008

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Action of the src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells

Cancer research (Chicago, Ill.), 2005-10, Vol.65 (20), p.9185-9189

2005

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Persistent Activation of Stat3 Signaling Induces Survivin Gene Expression and Confers Resistance to Apoptosis in Human Breast Cancer Cells

Clinical cancer research, 2006-01, Vol.12 (1), p.11-19

2006

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Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein

Molecular cancer therapeutics, 2006-03, Vol.5 (3), p.621-629

2006

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β1 Integrin Adhesion Enhances IL-6―Mediated STAT3 Signaling in Myeloma Cells: Implications for Microenvironment Influence on Tumor Survival and Proliferation

Cancer research (Chicago, Ill.), 2009-02, Vol.69 (3), p.1009-1015

2009

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Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3

Molecular cancer therapeutics, 2010-04, Vol.9 (4), p.953-962

2010

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STATs in cancer inflammation and immunity: a leading role for STAT3

The STATs of cancer - new molecular targets come of age

Differences and similarities between cancer and somatic stem cells: therapeutic implications

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors

miR‐194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice

Activated STAT Signaling in Human Tumors Provides Novel Molecular Targets for Therapeutic Intervention

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation

S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

Critical Role of STAT3 in IL-6―Mediated Drug Resistance in Human Neuroblastoma

Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance

Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells

Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer

Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways

General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors: Enantioselective Total Syntheses of (+)- and (−)-Gliocladine C, (+)-Leptosin D, (+)-T988C, (+)-Bionectin A, and (+)-Gliocladin A

Inhibition of Src Family Kinases with Dasatinib Blocks Migration and Invasion of Human Melanoma Cells

Action of the src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells

Persistent Activation of Stat3 Signaling Induces Survivin Gene Expression and Confers Resistance to Apoptosis in Human Breast Cancer Cells

Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein

β1 Integrin Adhesion Enhances IL-6―Mediated STAT3 Signaling in Myeloma Cells: Implications for Microenvironment Influence on Tumor Survival and Proliferation

Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3

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