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Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis

Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (4)

2021

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ATM Phosphorylation of Mdm2 Ser394 Regulates the Amplitude and Duration of the DNA Damage Response in Mice

Cancer cell, 2012-05, Vol.21 (5), p.668-679

2012

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The Wip1 Phosphatase Acts as a Gatekeeper in the p53-Mdm2 Autoregulatory Loop

Cancer cell, 2007-10, Vol.12 (4), p.342-354

2007

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The ING gene family in the regulation of cell growth and tumorigenesis

Journal of cellular physiology, 2009-01, Vol.218 (1), p.45-57

2009

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Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

Nature (London), 2010-10, Vol.467 (7318), p.977-981

2010

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Reassessment of the role of TSC, mTORC1 and microRNAs in amino acids-meditated translational control of TOP mRNAs

PloS one, 2014-10, Vol.9 (10), p.e109410-e109410

2014

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Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis

Cell reports (Cambridge), 2016-09, Vol.16 (10), p.2618-2629

2016

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DNA-Damage-Induced Nuclear Export of Precursor MicroRNAs Is Regulated by the ATM-AKT Pathway

Cell reports (Cambridge), 2013-06, Vol.3 (6), p.2100-2112

2013

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The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis

PloS one, 2008-02, Vol.3 (2), p.e1609

2008

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Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse

Developmental biology, 2010-04, Vol.340 (1), p.10-21

2010

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MicroRNA-34c Inversely Couples the Biological Functions of the Runt-related Transcription Factor RUNX2 and the Tumor Suppressor p53 in Osteosarcoma

The Journal of biological chemistry, 2013-07, Vol.288 (29), p.21307-21319

2013

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Requirement of JNK for Stress-Induced Activation of the Cytochrome c-Mediated Death Pathway

Science (American Association for the Advancement of Science), 2000-05, Vol.288 (5467), p.870-874

2000

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Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice

PloS one, 2014-06, Vol.9 (6), p.e100920

2014

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Inhibitor of growth-4 promotes IκB promoter activation to suppress NF-κB signaling and innate immunity

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (25), p.11423-11428

2010

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Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

The Journal of cell biology, 2006-03, Vol.172 (6), p.909-921

2006

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Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue

Cancer cell, 2003-11, Vol.4 (5), p.349-360

2003

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Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

Genes & development, 2003-08, Vol.17 (16), p.2021-2035

2003

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Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons

The Journal of neuroscience, 2011-08, Vol.31 (33), p.12029-12035

2011

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Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner

Journal of molecular cell biology, 2014-06, Vol.6 (3), p.255-266

2014

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Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs

Cell reports (Cambridge), 2017-12, Vol.21 (13), p.3691-3699

2017

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An essential role for Dicer in adipocyte differentiation

Journal of cellular biochemistry, 2010-07, Vol.110 (4), p.812-816

2010

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MicroRNA Biogenesis Is Required for Myc-Induced B-Cell Lymphoma Development and Survival

Cancer research (Chicago, Ill.), 2010-07, Vol.70 (14), p.6083-6092

2010

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ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (47), p.18519-18524

2008

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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

Nature (London), 1995-11, Vol.378 (6553), p.206-208

1995

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Phosphorylation of Serine 18 Regulates Distinct p53 Functions in Mice

Molecular and Cellular Biology, 2004-02, Vol.24 (3), p.976-984

2004

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Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis

ATM Phosphorylation of Mdm2 Ser394 Regulates the Amplitude and Duration of the DNA Damage Response in Mice

The Wip1 Phosphatase Acts as a Gatekeeper in the p53-Mdm2 Autoregulatory Loop

The ING gene family in the regulation of cell growth and tumorigenesis

Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

Reassessment of the role of TSC, mTORC1 and microRNAs in amino acids-meditated translational control of TOP mRNAs

Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis

DNA-Damage-Induced Nuclear Export of Precursor MicroRNAs Is Regulated by the ATM-AKT Pathway

The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis

Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse

MicroRNA-34c Inversely Couples the Biological Functions of the Runt-related Transcription Factor RUNX2 and the Tumor Suppressor p53 in Osteosarcoma

Requirement of JNK for Stress-Induced Activation of the Cytochrome c-Mediated Death Pathway

Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice

Inhibitor of growth-4 promotes IκB promoter activation to suppress NF-κB signaling and innate immunity

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons

Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner

Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs

An essential role for Dicer in adipocyte differentiation

MicroRNA Biogenesis Is Required for Myc-Induced B-Cell Lymphoma Development and Survival

ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

Phosphorylation of Serine 18 Regulates Distinct p53 Functions in Mice

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