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Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans

Physiological reviews, 2017-10, Vol.97 (4), p.1469-1528

2017

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Artificial intelligence and machine learning to fight COVID-19

Physiological genomics, 2020-04, Vol.52 (4), p.200-202

2020

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QTL mapping of rat blood pressure loci on RNO1 within a homologous region linked to human hypertension on HSA15

PloS one, 2019-08, Vol.14 (8), p.e0221658-e0221658

2019

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Circular RNAs in rat models of cardiovascular and renal diseases

Physiological genomics, 2017-09, Vol.49 (9), p.484-490

2017

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Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

Cell, 2018-10, Vol.175 (3), p.679-694.e22

2018

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Identification of Upstream Transcriptional Regulators of Ischemic Cardiomyopathy Using Cardiac RNA-Seq Meta-Analysis

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3472

2020

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Evidence for a link between gut microbiota and hypertension in the Dahl rat

Physiological genomics, 2015-06, Vol.47 (6), p.187-197

2015

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Genome-Wide Identification of Long Noncoding RNAs in Rat Models of Cardiovascular and Renal Disease

Hypertension (Dallas, Tex. 1979), 2015-01, Vol.65 (1), p.200-210

2015

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Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension

Cell reports (Cambridge), 2018-10, Vol.25 (3), p.677-689.e4

2018

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Cryptorchidism and infertility in rats with targeted disruption of the Adamts16 locus

PloS one, 2014-07, Vol.9 (7), p.e100967-e100967

2014

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Meta-Analysis of Dilated Cardiomyopathy Using Cardiac RNA-Seq Transcriptomic Datasets

Genes, 2020-01, Vol.11 (1), p.60

2020

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Microbiotal-Host Interactions and Hypertension

Physiology (Bethesda, Md.), 2017-05, Vol.32 (3), p.224-233

2017

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Positional cloning of quantitative trait nucleotides for blood pressure and cardiac QT-interval by targeted CRISPR/Cas9 editing of a novel long non-coding RNA

PLoS genetics, 2017-08, Vol.13 (8), p.e1006961

2017

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Bioinformatic analysis reveals new determinants of antigenic 14-3-3 proteins and a novel antifungal strategy

PloS one, 2017-12, Vol.12 (12), p.e0189503-e0189503

2017

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Microbiota Introduced to Germ-Free Rats Restores Vascular Contractility and Blood Pressure

Hypertension (Dallas, Tex. 1979), 2020-12, Vol.76 (6), p.1847-1855

2020

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Perceptions of US Medical Students on Artificial Intelligence in Medicine: Mixed Methods Survey Study

JMIR medical education, 2022-10, Vol.8 (4), p.e38325-e38325

2022

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Microbial Reconstitution Reverses Early Female Puberty Induced by Maternal High-fat Diet During Lactation

Endocrinology (Philadelphia), 2020-02, Vol.161 (2), p.1

2020

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Epigenetic histone modification by butyrate downregulates KIT and attenuates mast cell function

Journal of cellular and molecular medicine, 2023-10, Vol.27 (19), p.2983-2994

2023

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Spontaneous vascular dysfunction in Dahl salt‐sensitive male rats raised without a high‐salt diet

Physiological reports, 2024-07, Vol.12 (14), p.e16165-n/a

2024

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Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice

Cell metabolism, 2015-12, Vol.22 (6), p.983-996

2015

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Pleiotropic Effect of a High Resolution Mapped Blood Pressure QTL on Tumorigenesis

PloS one, 2016-04, Vol.11 (4), p.e0153519

2016

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Genetic predisposition for increased red blood cell distribution width is an early risk factor for cardiovascular and renal comorbidities

Disease models & mechanisms, 2020-05, Vol.13 (5)

2020

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Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension - 2021 NHLBI Workshop Report

Hypertension (Dallas, Tex. 1979), 2023-03, Vol.80 (3), p.503-522

2023

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Immunoglobulin A, an Active Liaison for Host-Microbiota Homeostasis

Microorganisms (Basel), 2021-10, Vol.9 (10), p.2117

2021

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Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats

Pharmacological research, 2023-10, Vol.196, p.106920-106920, Article 106920

2023

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Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans

Artificial intelligence and machine learning to fight COVID-19

QTL mapping of rat blood pressure loci on RNO1 within a homologous region linked to human hypertension on HSA15

Circular RNAs in rat models of cardiovascular and renal diseases

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

Identification of Upstream Transcriptional Regulators of Ischemic Cardiomyopathy Using Cardiac RNA-Seq Meta-Analysis

Evidence for a link between gut microbiota and hypertension in the Dahl rat

Genome-Wide Identification of Long Noncoding RNAs in Rat Models of Cardiovascular and Renal Disease

Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension

Cryptorchidism and infertility in rats with targeted disruption of the Adamts16 locus

Meta-Analysis of Dilated Cardiomyopathy Using Cardiac RNA-Seq Transcriptomic Datasets

Microbiotal-Host Interactions and Hypertension

Positional cloning of quantitative trait nucleotides for blood pressure and cardiac QT-interval by targeted CRISPR/Cas9 editing of a novel long non-coding RNA

Bioinformatic analysis reveals new determinants of antigenic 14-3-3 proteins and a novel antifungal strategy

Microbiota Introduced to Germ-Free Rats Restores Vascular Contractility and Blood Pressure

Perceptions of US Medical Students on Artificial Intelligence in Medicine: Mixed Methods Survey Study

Microbial Reconstitution Reverses Early Female Puberty Induced by Maternal High-fat Diet During Lactation

Epigenetic histone modification by butyrate downregulates KIT and attenuates mast cell function

Spontaneous vascular dysfunction in Dahl salt‐sensitive male rats raised without a high‐salt diet

Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice

Pleiotropic Effect of a High Resolution Mapped Blood Pressure QTL on Tumorigenesis

Genetic predisposition for increased red blood cell distribution width is an early risk factor for cardiovascular and renal comorbidities

Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension - 2021 NHLBI Workshop Report

Immunoglobulin A, an Active Liaison for Host-Microbiota Homeostasis

Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats

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