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A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells

Nature chemical biology, 2020-05, Vol.16 (5), p.513

2020

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Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage

Nature communications, 2022-03, Vol.13 (1), p.1323-1323, Article 1323

2022

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Design of fast proteolysis-based signaling and logic circuits in mammalian cells

Nature chemical biology, 2019-02, Vol.15 (2), p.115

2019

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DNA-Free Genome Editing of Brassica oleracea and B. rapa Protoplasts Using CRISPR-Cas9 Ribonucleoprotein Complexes

Frontiers in plant science, 2018-11, Vol.9, p.1594-1594

2018

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Segmentation strategy of de novo designed four-helical bundles expands protein oligomerization modalities for cell regulation

Nature communications, 2023-04, Vol.14 (1), p.1995-1995, Article 1995

2023

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Self-assembly and regulation of protein cages from pre-organised coiled-coil modules

Nature communications, 2021-02, Vol.12 (1), p.939-12, Article 939

2021

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The molecular mechanism of species-specific recognition of lipopolysaccharides by the MD-2/TLR4 receptor complex

Molecular immunology, 2015-02, Vol.63 (2), p.134-142

2015

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Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines

The Journal of immunology (1950), 2011-04, Vol.186 (8), p.4794-4804

2011

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Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion

Scientific reports, 2021-04, Vol.11 (1), p.9136-9136, Article 9136

2021

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NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway

Nature communications, 2018-12, Vol.9 (1), p.5182-18, Article 5182

2018

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Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments

Nature chemical biology, 2013-06, Vol.9 (6), p.362

2013

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Designed folding pathway of modular coiled-coil-based proteins

Nature communications, 2021-02, Vol.12 (1), p.940-940, Article 940

2021

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Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA

The Journal of immunology (1950), 2017-03, Vol.198 (5), p.2093-2104

2017

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Chemistry of Lipid A: At the Heart of Innate Immunity

Chemistry : a European journal, 2015-01, Vol.21 (2), p.500-519

2015

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MD-2 determinants of nickel and cobalt-mediated activation of human TLR4

PloS one, 2015-03, Vol.10 (3), p.e0120583

2015

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The role of the C-terminal D0 domain of flagellin in activation of Toll like receptor 5

PLoS pathogens, 2017-08, Vol.13 (8), p.e1006574-e1006574

2017

Volltextzugriff (PDF)

Disruption of disulfides within RBD of SARS‐CoV‐2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs

The FASEB journal, 2021-06, Vol.35 (6), p.e21651-n/a

2021

Volltextzugriff (PDF)

Author Correction: Self-assembly and regulation of protein cages from pre-organised coiled-coil modules

Nature communications, 2021-03, Vol.12 (1), p.1811-1811, Article 1811

2021

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Programmable de novo designed coiled coil-mediated phase separation in mammalian cells

Nature communications, 2023-12, Vol.14 (1), p.7973-7973, Article 7973

2023

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A multiplexed bacterial two-hybrid for rapid characterization of protein-protein interactions and iterative protein design

Nature communications, 2023-08, Vol.14 (1), p.4636-4636, Article 4636

2023

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Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9

Nature communications, 2017-05, Vol.8 (1), p.15363-15363, Article 15363

2017

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Species-specific activation of TLR4 by hypoacylated endotoxins governed by residues 82 and 122 of MD-2

PloS one, 2014-09, Vol.9 (9), p.e107520-e107520

2014

Volltextzugriff (PDF)

Coiled-coil heterodimer-based recruitment of an exonuclease to CRISPR/Cas for enhanced gene editing

Nature communications, 2022-06, Vol.13 (1), p.3604-3604, Article 3604

2022

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DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

Nucleic acids research, 2012-02, Vol.40 (4), p.1879

2012

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The Role of UNC93B1 Protein in Surface Localization of TLR3 Receptor and in Cell Priming to Nucleic Acid Agonists

The Journal of biological chemistry, 2013-01, Vol.288 (1), p.442-454

2013

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A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells

Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage

Design of fast proteolysis-based signaling and logic circuits in mammalian cells

DNA-Free Genome Editing of Brassica oleracea and B. rapa Protoplasts Using CRISPR-Cas9 Ribonucleoprotein Complexes

Segmentation strategy of de novo designed four-helical bundles expands protein oligomerization modalities for cell regulation

Self-assembly and regulation of protein cages from pre-organised coiled-coil modules

The molecular mechanism of species-specific recognition of lipopolysaccharides by the MD-2/TLR4 receptor complex

Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines

Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion

NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway

Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments

Designed folding pathway of modular coiled-coil-based proteins

Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA

Chemistry of Lipid A: At the Heart of Innate Immunity

MD-2 determinants of nickel and cobalt-mediated activation of human TLR4

The role of the C-terminal D0 domain of flagellin in activation of Toll like receptor 5

Disruption of disulfides within RBD of SARS‐CoV‐2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs

Author Correction: Self-assembly and regulation of protein cages from pre-organised coiled-coil modules

Programmable de novo designed coiled coil-mediated phase separation in mammalian cells

A multiplexed bacterial two-hybrid for rapid characterization of protein-protein interactions and iterative protein design

Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9

Species-specific activation of TLR4 by hypoacylated endotoxins governed by residues 82 and 122 of MD-2

Coiled-coil heterodimer-based recruitment of an exonuclease to CRISPR/Cas for enhanced gene editing

DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

The Role of UNC93B1 Protein in Surface Localization of TLR3 Receptor and in Cell Priming to Nucleic Acid Agonists

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