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Development of autotaxin inhibitors: A series of zinc binding triazoles

Bioorganic & medicinal chemistry letters, 2018-07, Vol.28 (13), p.2279-2284

2018

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Synthesis of the Marine Sponge Derived β2-Adrenoceptor Agonist S1319

Organic letters, 2005-10, Vol.7 (21), p.4697-4700

2005

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The Identification of Indacaterol as an Ultralong-Acting Inhaled β2-Adrenoceptor Agonist

Journal of medicinal chemistry, 2010-05, Vol.53 (9), p.3675-3684

2010

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The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (15), p.3285-3290

2014

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An investigation into the structure-activity relationships associated with the systematic modification of the β(2)-adrenoceptor agonist indacaterol

Bioorganic & medicinal chemistry letters, 2012-10, Vol.22 (19), p.6280-6285

2012

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An investigation into the structure–activity relationships associated with the systematic modification of the β2-adrenoceptor agonist indacaterol

Bioorganic & medicinal chemistry letters, 2012-10, Vol.22 (19), p.6280-6285

2012

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The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist

Bioorganic & medicinal chemistry letters, 2014-09, Vol.24 (17), p.4341-4347

2014

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A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β2-adrenoceptor agonists as inhaled long-acting bronchodilators

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5302-5307

2010

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Synthesis of the marine sponge derived beta2-adrenoceptor agonist S1319

Organic letters, 2005-10, Vol.7 (21), p.4697-4700

2005

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An investigation into the structure-activity relationships associated with the systematic modification of the [beta]2-adrenoceptor agonist indacaterol

Bioorganic & medicinal chemistry letters, 2012-10, Vol.22 (19), p.6280-6285

2012

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Synthesis of the Marine Sponge Derived β 2 -Adrenoceptor Agonist S1319

Organic letters, 2005-10, Vol.7 (21), p.4697-4700

2005

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Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the β 2-adrenoceptor activity

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (18), p.4705-4710

2004

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A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β 2-adrenoceptor agonists as inhaled long-acting bronchodilators

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (17), p.5302-5307

2010

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The Identification of Indacaterol as an Ultralong-Acting Inhaled β 2 -Adrenoceptor Agonist

Journal of medicinal chemistry, 2010-05, Vol.53 (9), p.3675-3684

2010

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A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of beta2-adrenoceptor agonists as inhaled long-acting bronchodilators

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5302-5307

2010

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Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the beta2-adrenoceptor activity

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (18), p.4705-4710

2004

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Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the β2-adrenoceptor activity

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (18), p.4705-4710

2004

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Design and Synthesis of Thrombin Inhibitors: Analogues of MD-805 with Reduced Stereogenicity and Improved Potency

Journal of medicinal chemistry, 1999-11, Vol.42 (22), p.4584-4603

1999

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The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist

Journal of medicinal chemistry, 2010-05, Vol.53 (9), p.3675-3684

2010

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The Discovery of orally available thrombin inhibitors : Studies towards the optimisation of CGH1668

Bioorganic & medicinal chemistry letters, 1998-12, Vol.8 (24), p.3583-3588

1998

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The design and synthesis of thrombin inhibitors: analogues of MD805 containing non-polar surrogates for arginine at the P1 position

Bioorganic & medicinal chemistry letters, 2000-07, Vol.10 (14), p.1563-1566

2000

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Studies towards the identification of potent, selective and bioavailable thrombin inhibitors

Bioorganic & medicinal chemistry letters, 1999-03, Vol.9 (5), p.737-742

1999

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The discovery of orally available thrombin inhibitors: Optimisation of the P1 pharmacophore

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (8), p.1103-1108

1999

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Optimisation of the P2 pharmacophore in a series of thrombin inhibitors: Ion-dipole interactions with lysine 60G

Bioorganic & medicinal chemistry letters, 1999-05, Vol.9 (9), p.1317-1322

1999

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Synthesis of the Marine Sponge Derived β 2 ‐Adrenoceptor Agonist S1319

ChemInform, 2006-02, Vol.37 (9)

2006

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Development of autotaxin inhibitors: A series of zinc binding triazoles

Synthesis of the Marine Sponge Derived β2-Adrenoceptor Agonist S1319

The Identification of Indacaterol as an Ultralong-Acting Inhaled β2-Adrenoceptor Agonist

The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists

An investigation into the structure-activity relationships associated with the systematic modification of the β(2)-adrenoceptor agonist indacaterol

An investigation into the structure–activity relationships associated with the systematic modification of the β2-adrenoceptor agonist indacaterol

The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist

A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β2-adrenoceptor agonists as inhaled long-acting bronchodilators

Synthesis of the marine sponge derived beta2-adrenoceptor agonist S1319

An investigation into the structure-activity relationships associated with the systematic modification of the [beta]2-adrenoceptor agonist indacaterol

Synthesis of the Marine Sponge Derived β 2 -Adrenoceptor Agonist S1319

Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the β 2-adrenoceptor activity

A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β 2-adrenoceptor agonists as inhaled long-acting bronchodilators

The Identification of Indacaterol as an Ultralong-Acting Inhaled β 2 -Adrenoceptor Agonist

A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of beta2-adrenoceptor agonists as inhaled long-acting bronchodilators

Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the beta2-adrenoceptor activity

Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the β2-adrenoceptor activity

Design and Synthesis of Thrombin Inhibitors: Analogues of MD-805 with Reduced Stereogenicity and Improved Potency

The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist

The Discovery of orally available thrombin inhibitors : Studies towards the optimisation of CGH1668

The design and synthesis of thrombin inhibitors: analogues of MD805 containing non-polar surrogates for arginine at the P1 position

Studies towards the identification of potent, selective and bioavailable thrombin inhibitors

The discovery of orally available thrombin inhibitors: Optimisation of the P1 pharmacophore

Optimisation of the P2 pharmacophore in a series of thrombin inhibitors: Ion-dipole interactions with lysine 60G

Synthesis of the Marine Sponge Derived β 2 ‐Adrenoceptor Agonist S1319

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