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Drug‐induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine

British journal of pharmacology, 2006-11, Vol.149 (5), p.481-489

2006

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Mechanism of Block and Identification of the Verapamil Binding Domain to HERG Potassium Channels

Circulation research, 1999-05, Vol.84 (9), p.989-998

1999

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Coexistence of hERG current block and disruption of protein trafficking in ketoconazole‐induced long QT syndrome

British journal of pharmacology, 2008-02, Vol.153 (3), p.439-447

2008

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Adverse Effects of Low Dose Amiodarone: A Meta-Analysis

Journal of the American College of Cardiology, 1997-09, Vol.30 (3), p.791-798

1997

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Properties of HERG Channels Stably Expressed in HEK 293 Cells Studied at Physiological Temperature

Biophysical journal, 1998, Vol.74 (1), p.230-241

1998

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Novel mechanism associated with an inherited cardiac arrhythmia : Defective protein trafficking by the mutant HERG (G601S) potassium channel

Circulation (New York, N.Y.), 1999-05, Vol.99 (17), p.2290-2294

1999

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[ 3H]Dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen

European journal of pharmacology, 2001-10, Vol.430 (1), p.147-148

2001

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Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride

American journal of physiology. Heart and circulatory physiology, 1997-11, Vol.273 (5), p.H2534-H2538

1997

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Torsade de Pointes with an antihistamine metabolite: Potassium channel blockade with desmethylastemizole

Journal of the American College of Cardiology, 1996-11, Vol.28 (6), p.1556-1561

1996

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Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects

The Journal of biological chemistry, 1999-10, Vol.274 (44), p.31123-31126

1999

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HERG trafficking and pharmacological rescue of LQTS-2 mutant channels

Handbook of experimental pharmacology, 2006 (171), p.349

2006

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HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

The Journal of biological chemistry, 1998-08, Vol.273 (33), p.21061-21066

1998

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Triggered activity in the heart: cellular mechanisms of early after-depolarizations

European heart journal, 1991-12, Vol.12 (suppl-F), p.4-9

1991

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Direct Measurement of L-Type Ca2+ Window Current in Heart Cells

Circulation research, 1992-03, Vol.70 (3), p.445-455

1992

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Thapsigargin Selectively Rescues the Trafficking Defective LQT2 Channels G601S and F805C

The Journal of biological chemistry, 2003-09, Vol.278 (37), p.35749-35754

2003

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Block of HERG Potassium Channels by the Antihistamine Astemizole and its Metabolites Desmethylastemizole and Norastemizole

Journal of cardiovascular electrophysiology, 1999-06, Vol.10 (6), p.836-843

1999

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Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2

Journal of cardiovascular electrophysiology, 2000-12, Vol.11 (12), p.1413-1418

2000

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Blockade of HERG channels by HIV protease inhibitors

The Lancet (British edition), 2005-02, Vol.365 (9460), p.682-686

2005

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Interaction with GM130 during HERG Ion Channel Trafficking. Disruption by Type 2 Congenital Long QT Syndrome Mutations

The Journal of biological chemistry, 2002-12, Vol.277 (49), p.47779-47785

2002

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Inactivation properties of T-type calcium current in canine cardiac Purkinje cells

Biophysical journal, 1989-11, Vol.56 (5), p.1007-1016

1989

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Droperidol Lengthens Cardiac Repolarization due to Block of the Rapid Component of the Delayed Rectifier Potassium Current

Journal of cardiovascular electrophysiology, 1999-12, Vol.10 (12), p.1597-1604

1999

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New Studies of the Excitatory Sodium Currents in Heart Muscle

Circulation research, 1985-04, Vol.56 (4), p.475-486

1985

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Sodium current in voltage clamped internally perfused canine cardiac Purkinje cells

Biophysical journal, 1987-07, Vol.52 (1), p.1-11

1987

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Cocaine Blocks HERG, but Not KvLQT1+minK, Potassium Channels

Molecular pharmacology, 2001-05, Vol.59 (5), p.1069-1076

2001

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Enhancement of delayed afterdepolarizations and triggered activity by class III antiarrhythmic drugs : Multiple effects of E-4031 and dofetilide

Methods and Findings in Experimental and Clinical Pharmacology, 2000-03, Vol.22 (2), p.67-76

2000

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Drug‐induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine

Mechanism of Block and Identification of the Verapamil Binding Domain to HERG Potassium Channels

Coexistence of hERG current block and disruption of protein trafficking in ketoconazole‐induced long QT syndrome

Adverse Effects of Low Dose Amiodarone: A Meta-Analysis

Properties of HERG Channels Stably Expressed in HEK 293 Cells Studied at Physiological Temperature

Novel mechanism associated with an inherited cardiac arrhythmia : Defective protein trafficking by the mutant HERG (G601S) potassium channel

[ 3H]Dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen

Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride

Torsade de Pointes with an antihistamine metabolite: Potassium channel blockade with desmethylastemizole

Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects

HERG trafficking and pharmacological rescue of LQTS-2 mutant channels

HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

Triggered activity in the heart: cellular mechanisms of early after-depolarizations

Direct Measurement of L-Type Ca2+ Window Current in Heart Cells

Thapsigargin Selectively Rescues the Trafficking Defective LQT2 Channels G601S and F805C

Block of HERG Potassium Channels by the Antihistamine Astemizole and its Metabolites Desmethylastemizole and Norastemizole

Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2

Blockade of HERG channels by HIV protease inhibitors

Interaction with GM130 during HERG Ion Channel Trafficking. Disruption by Type 2 Congenital Long QT Syndrome Mutations

Inactivation properties of T-type calcium current in canine cardiac Purkinje cells

Droperidol Lengthens Cardiac Repolarization due to Block of the Rapid Component of the Delayed Rectifier Potassium Current

New Studies of the Excitatory Sodium Currents in Heart Muscle

Sodium current in voltage clamped internally perfused canine cardiac Purkinje cells

Cocaine Blocks HERG, but Not KvLQT1+minK, Potassium Channels

Enhancement of delayed afterdepolarizations and triggered activity by class III antiarrhythmic drugs : Multiple effects of E-4031 and dofetilide

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