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5'-Chalcogen-Substituted Nucleoside Pyrophosphate and Phosphate Monoester Analogues: Preparation and Hydrolysis Studies

International journal of molecular sciences, 2022-12, Vol.23 (24), p.15582

2022

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Introductory Medicinal Chemistry for Pharmacy Students: An Assignment-Based Online Assessment Strategy

Journal of chemical education, 2024-07, Vol.101 (7), p.2887-2891

Jakeman, David L.

2024

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α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (34), p.12384-12389

2014

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Synthesis of a novel fluorinated phosphonyl C-glycoside, (3-deoxy-3-fluoro-β-d-glucopyranosyl)methylphosphonate, a potential inhibitor of β-phosphoglucomutase

Carbohydrate research, 2023-12, Vol.534, p.108979-108979, Article 108979

2023

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Eight-Membered Ring-Containing Jadomycins: Implications for Non-enzymatic Natural Products Biosynthesis

Journal of the American Chemical Society, 2015-03, Vol.137 (9), p.3271-3275

2015

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Characterization of l‑Digitoxosyl-phenanthroviridin from Streptomyces venezuelae ISP5230

Journal of natural products (Washington, D.C.), 2015-08, Vol.78 (8), p.1942-1948

2015

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Isolation and Synthetic Diversification of Jadomycin 4‑Amino‑l‑phenylalanine

Journal of natural products (Washington, D.C.), 2015-06, Vol.78 (6), p.1208-1214

2015

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Synthesis and antimalarial activity of prodigiosenes

Organic & biomolecular chemistry, 2014-06, Vol.12 (24), p.4132-4142

2014

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Synthesis and Evaluation of l‑Rhamnose 1C-Phosphonates as Nucleotidylyltransferase Inhibitors

Journal of organic chemistry, 2013-10, Vol.78 (19), p.9822-9833

2013

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Antimicrobial Activities of Jadomycin B and Structurally Related Analogues

Antimicrobial Agents and Chemotherapy, 2009-03, Vol.53 (3), p.1245-1247

2009

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Isolation of a jadomycin incorporating L-ornithine, analysis of antimicrobial activity and jadomycin reactive oxygen species (ROS) generation in MDA-MB-231 breast cancer cells

Journal of antibiotics, 2018-08, Vol.71 (8), p.722-730

2018

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Stereoselective Chemical Synthesis of Sugar Nucleotides via Direct Displacement of Acylated Glycosyl Bromides

Organic letters, 2007-03, Vol.9 (7), p.1227-1230

2007

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Diverse DNA-Cleaving Capacities of the Jadomycins through Precursor-Directed Biosynthesis

Organic letters, 2010-03, Vol.12 (6), p.1172-1175

2010

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Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono‑, Di‑, and Trifluorinated d‑Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition

ACS omega, 2019-04, Vol.4 (4), p.7029-7037

2019

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Structural and dynamical description of the enzymatic reaction of a phosphohexomutase

Structural dynamics (Melville, N.Y.), 2019-03, Vol.6 (2), p.024703-024703

2019

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Jadomycins, put a bigger ring in it: isolation of seven- to ten-membered ring analogues

Chemical communications (Cambridge, England), 2015-10, Vol.51 (78), p.14617-14619

2015

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Jadomycins Derived from the Assimilation and Incorporation of Norvaline and Norleucine

Journal of natural products (Washington, D.C.), 2011-11, Vol.74 (11), p.2420-2424

2011

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Synthesis of 5′-Thymidine-Conjugated Formylphenylboronic Acids as Potential Lysine Targeting Iminoboronate Reversible Covalent Enzyme Probes

Journal of organic chemistry, 2022-11, Vol.87 (21), p.13542-13555

2022

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On the Catalytic Activity of a GT1 Family Glycosyltransferase from Streptomyces venezuelae ISP5230

Journal of organic chemistry, 2019-09, Vol.84 (18), p.11482-11492

2019

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Stereochemical Integrity of Oxazolone Ring-Containing Jadomycins

Chembiochem : a European journal of chemical biology, 2007-07, Vol.8 (10), p.1198-1203

2007

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Structure-Activity Analysis of Quorum-Sensing Signaling Peptides from Streptococcus mutans

Journal of Bacteriology, 2007-02, Vol.189 (4), p.1441-1450

2007

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Synthesis of α‑Deoxymono and Difluorohexopyranosyl 1‑Phosphates and Kinetic Evaluation with Thymidylyl- and Guanidylyltransferases

Journal of organic chemistry, 2016-10, Vol.81 (19), p.8816-8825

2016

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Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites

The Journal of biological chemistry, 2022-02, Vol.298 (2), p.101550-101550, Article 101550

2022

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Jadomycins Inhibit Type II Topoisomerases and Promote DNA Damage and Apoptosis in Multidrug-Resistant Triple-Negative Breast Cancer Cells

The Journal of pharmacology and experimental therapeutics, 2017-11, Vol.363 (2), p.196

2017

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Inhibitory Evaluation of αPMM/PGM from Pseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study

Journal of organic chemistry, 2019-08, Vol.84 (15), p.9627-9636

2019

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5'-Chalcogen-Substituted Nucleoside Pyrophosphate and Phosphate Monoester Analogues: Preparation and Hydrolysis Studies

Introductory Medicinal Chemistry for Pharmacy Students: An Assignment-Based Online Assessment Strategy

α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction

Synthesis of a novel fluorinated phosphonyl C-glycoside, (3-deoxy-3-fluoro-β-d-glucopyranosyl)methylphosphonate, a potential inhibitor of β-phosphoglucomutase

Eight-Membered Ring-Containing Jadomycins: Implications for Non-enzymatic Natural Products Biosynthesis

Characterization of l‑Digitoxosyl-phenanthroviridin from Streptomyces venezuelae ISP5230

Isolation and Synthetic Diversification of Jadomycin 4‑Amino‑l‑phenylalanine

Synthesis and antimalarial activity of prodigiosenes

Synthesis and Evaluation of l‑Rhamnose 1C-Phosphonates as Nucleotidylyltransferase Inhibitors

Antimicrobial Activities of Jadomycin B and Structurally Related Analogues

Isolation of a jadomycin incorporating L-ornithine, analysis of antimicrobial activity and jadomycin reactive oxygen species (ROS) generation in MDA-MB-231 breast cancer cells

Stereoselective Chemical Synthesis of Sugar Nucleotides via Direct Displacement of Acylated Glycosyl Bromides

Diverse DNA-Cleaving Capacities of the Jadomycins through Precursor-Directed Biosynthesis

Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono‑, Di‑, and Trifluorinated d‑Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition

Structural and dynamical description of the enzymatic reaction of a phosphohexomutase

Jadomycins, put a bigger ring in it: isolation of seven- to ten-membered ring analogues

Jadomycins Derived from the Assimilation and Incorporation of Norvaline and Norleucine

Synthesis of 5′-Thymidine-Conjugated Formylphenylboronic Acids as Potential Lysine Targeting Iminoboronate Reversible Covalent Enzyme Probes

On the Catalytic Activity of a GT1 Family Glycosyltransferase from Streptomyces venezuelae ISP5230

Stereochemical Integrity of Oxazolone Ring-Containing Jadomycins

Structure-Activity Analysis of Quorum-Sensing Signaling Peptides from Streptococcus mutans

Synthesis of α‑Deoxymono and Difluorohexopyranosyl 1‑Phosphates and Kinetic Evaluation with Thymidylyl- and Guanidylyltransferases

Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites

Jadomycins Inhibit Type II Topoisomerases and Promote DNA Damage and Apoptosis in Multidrug-Resistant Triple-Negative Breast Cancer Cells

Inhibitory Evaluation of αPMM/PGM from Pseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study

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