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Interaction of cationic porphyrins with DNA: importance of the number and position of the charges and minimum structural requirements for intercalation

Biochemistry (Easton), 1990-05, Vol.29 (17), p.4205-4215

1990

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Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II

Cancer research (Chicago, Ill.), 1989-09, Vol.49 (18), p.5111-5117

1989

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Mechanisms of action in NIH-3T3 cells of genistein, an inhibitor of EGF receptor tyrosine kinase activity

Biochemical pharmacology, 1990, Vol.39 (1), p.187-193

1990

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Interaction of DNA intercalator 3-nitrobenzothiazolo (3,2-a)quinolinium with DNA topoisomerases: a possible-mechanism for its biological activity

Molecular pharmacology, 1990-03, Vol.37 (3), p.377-382

1990

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Modulation of the antitumor activity by methyl substitutions in the series of 7H-pyridocarbazole monomers and dimers

Journal of medicinal chemistry, 1987-11, Vol.30 (11), p.2074-2080

1987

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The Noncovalent Complex between DNA and the Bifunctional Intercalator Ditercalinium is a Substrate for the UvrABC Endonuclease of Escherichia coli

Proceedings of the National Academy of Sciences - PNAS, 1989-09, Vol.86 (17), p.6557-6561

1989

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Betulinic Acid Derivatives: A New Class of Specific Inhibitors of Human Immunodeficiency Virus Type 1 Entry

Journal of medicinal chemistry, 1996-03, Vol.39 (5), p.1069-1083

1996

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Mode of interaction and apparent binding constants of meso-tetraaryl porphyrins bearing between one and four positive charges with DNA

Biochemical and biophysical research communications, 1986-12, Vol.141 (2), p.643-649

1986

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Structure-Activity Relationships in a Series of 5-[(2,5-Dihydroxybenzyl)amino]salicylate Inhibitors of EGF-Receptor-Associated Tyrosine Kinase: Importance of Additional Hydrophobic Aromatic Interactions

Journal of medicinal chemistry, 1994-03, Vol.37 (6), p.845-859

1994

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Betulinic Acid Derivatives: A New Class of Human Immunodeficiency Virus Type 1 Specific Inhibitors with a New Mode of Action

Journal of medicinal chemistry, 1996-03, Vol.39 (5), p.1056-1068

1996

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Triterpene derivatives that block entry of human immunodeficiency virus type 1 into cells

Proceedings of the National Academy of Sciences - PNAS, 1994-04, Vol.91 (9), p.3564-3568

1994

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A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

Journal of translational medicine, 2005-02, Vol.3 (1), p.9-9, Article 9

2005

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Asymmetrical bisintercalators as potential antitumor agents

Journal of medicinal chemistry, 1988-05, Vol.31 (5), p.1021-1026

1988

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Production and characterization of clinical grade exosomes derived from dendritic cells

Journal of immunological methods, 2002-12, Vol.270 (2), p.211-226

2002

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Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

Journal of translational medicine, 2005-03, Vol.3 (1), p.10-10, Article 10

2005

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Synthesis and binding properties to DNA and to opioid receptors of enkephalin-ellipticinium conjugates

International Journal of Peptide and Protein Research, 1987-09, Vol.30 (3), p.347-355

1987

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Decay of Fluorescence Emission Anisotropy of the Ethidium Bromide-DNA Complex Evidence for an Internal Motion in DNA

Proceedings of the National Academy of Sciences - PNAS, 1970-02, Vol.65 (2), p.417-421

1970

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Round table chaired by Laurent Broomhead

Annales pharmaceutiques françaises, 2005-09, Vol.63 (5), p.312-328

2005

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Table ronde animée par Laurent Broomhead

Annales pharmaceutiques françaises, 2005-09, Vol.63 (5), p.312-328

2005

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Exosome Display technology: Applications to the development of new diagnostics and therapeutics

Blood cells, molecules, & diseases, 2005-09, Vol.35 (2), p.158-168

2005

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DNA Polyintercalating Drugs: DNA Binding of Diacridine Derivatives

Proceedings of the National Academy of Sciences - PNAS, 1975-08, Vol.72 (8), p.2915-2919

1975

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Another Link between Phospholipid Transmembrane Migration and ABC Transporter Gene Family, Inferred from a Rare Inherited Disorder of Phosphatidylserine Externalization

Biochemical and biophysical research communications, 1997-12, Vol.241 (2), p.548-552

1997

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Synthesis and biological activity of new dimers in the 7H-pyrido[4,3-c]carbazole antitumor series

Journal of medicinal chemistry, 1992-01, Vol.35 (1), p.72-81

1992

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DNase I susceptibility of bent DNA and its alteration by ditercalinium and distamycin

Biochemistry (Easton), 1990-05, Vol.29 (21), p.5035-5043

1990

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Dynamic structure of DNA complexes. Fluorometric measurement of hydrogen-deuterium exchange kinetics of DNA-bound ethidium dimer and acridine-ethidium dimer

Biochemistry (Easton), 1983-06, Vol.22 (13), p.3231-3237

1983

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Interaction of cationic porphyrins with DNA: importance of the number and position of the charges and minimum structural requirements for intercalation

Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II

Mechanisms of action in NIH-3T3 cells of genistein, an inhibitor of EGF receptor tyrosine kinase activity

Interaction of DNA intercalator 3-nitrobenzothiazolo (3,2-a)quinolinium with DNA topoisomerases: a possible-mechanism for its biological activity

Modulation of the antitumor activity by methyl substitutions in the series of 7H-pyridocarbazole monomers and dimers

The Noncovalent Complex between DNA and the Bifunctional Intercalator Ditercalinium is a Substrate for the UvrABC Endonuclease of Escherichia coli

Betulinic Acid Derivatives: A New Class of Specific Inhibitors of Human Immunodeficiency Virus Type 1 Entry

Mode of interaction and apparent binding constants of meso-tetraaryl porphyrins bearing between one and four positive charges with DNA

Structure-Activity Relationships in a Series of 5-[(2,5-Dihydroxybenzyl)amino]salicylate Inhibitors of EGF-Receptor-Associated Tyrosine Kinase: Importance of Additional Hydrophobic Aromatic Interactions

Betulinic Acid Derivatives: A New Class of Human Immunodeficiency Virus Type 1 Specific Inhibitors with a New Mode of Action

Triterpene derivatives that block entry of human immunodeficiency virus type 1 into cells

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

Asymmetrical bisintercalators as potential antitumor agents

Production and characterization of clinical grade exosomes derived from dendritic cells

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

Synthesis and binding properties to DNA and to opioid receptors of enkephalin-ellipticinium conjugates

Decay of Fluorescence Emission Anisotropy of the Ethidium Bromide-DNA Complex Evidence for an Internal Motion in DNA

Round table chaired by Laurent Broomhead

Table ronde animée par Laurent Broomhead

Exosome Display technology: Applications to the development of new diagnostics and therapeutics

DNA Polyintercalating Drugs: DNA Binding of Diacridine Derivatives

Another Link between Phospholipid Transmembrane Migration and ABC Transporter Gene Family, Inferred from a Rare Inherited Disorder of Phosphatidylserine Externalization

Synthesis and biological activity of new dimers in the 7H-pyrido[4,3-c]carbazole antitumor series

DNase I susceptibility of bent DNA and its alteration by ditercalinium and distamycin

Dynamic structure of DNA complexes. Fluorometric measurement of hydrogen-deuterium exchange kinetics of DNA-bound ethidium dimer and acridine-ethidium dimer

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