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Distinct functions of AKT isoforms in breast cancer: a comprehensive review

Cell communication and signaling, 2019-11, Vol.17 (1), p.154-154, Article 154

2019

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The Role of mTOR Signaling as a Therapeutic Target in Cancer

International journal of molecular sciences, 2021-02, Vol.22 (4), p.1743

2021

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The Functional Role of Extracellular Matrix Proteins in Cancer

Cancers, 2022-01, Vol.14 (1), p.238

2022

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The Role of PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma Metabolism

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2652

2023

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The Functional Roles of the Src Homology 2 Domain-Containing Inositol 5-Phosphatases SHIP1 and SHIP2 in the Pathogenesis of Human Diseases

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5254

2024

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Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia

Nature communications, 2021-06, Vol.12 (1), p.3526-3526, Article 3526

2021

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AKT in Bone Metastasis of Solid Tumors: A Comprehensive Review

Cancers, 2021-05, Vol.13 (10), p.2287

2021

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Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects

Clinical cancer research, 2015-05, Vol.21 (10), p.2388-2398

2015

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Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells

Molecular cancer, 2012-11, Vol.11 (1), p.85-85, Article 85

2012

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Combined targeting of AKT and mTOR using MK‐2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma

International journal of cancer, 2013-11, Vol.133 (9), p.2065-2076

2013

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Tight Junction Proteins Claudin-1 and Occludin Are Important for Cutaneous Wound Healing

The American journal of pathology, 2017-06, Vol.187 (6), p.1301-1312

2017

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Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells

PloS one, 2016-05, Vol.11 (5), p.e0154745-e0154745

2016

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Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4

PloS one, 2016-01, Vol.11 (1), p.e0146370-e0146370

2016

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All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines

International journal of molecular sciences, 2024-02, Vol.25 (4), p.2168

2024

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Differential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer

Clinical & experimental metastasis, 2020-12, Vol.37 (6), p.649-656

2020

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Combined Targeting of AKT and mTOR Inhibits Proliferation of Human NF1-Associated Malignant Peripheral Nerve Sheath Tumour Cells In Vitro but not in a Xenograft Mouse Model In Vivo

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1548

2020

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Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway

Cell communication and signaling, 2024-07, Vol.22 (1), p.1-23, Article 360

2024

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Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors

Investigational new drugs, 2014-12, Vol.32 (6), p.1144-1154

2014

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Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic Acid-induced 2

Cancer discovery, 2015-05, Vol.5 (5), p.506-519

2015

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PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

Oncotarget, 2017-01, Vol.8 (4), p.6155-6168

2017

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PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer

Biochemical pharmacology, 2020-02, Vol.172, p.113729-113729, Article 113729

2020

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Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis

Frontiers in oncology, 2023-07, Vol.13, p.1129682-1129682

2023

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Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia

Oncotarget, 2017-04, Vol.8 (17), p.29187-29201

2017

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Generating Patient-Derived HCC Cell Lines Suitable for Predictive In Vitro and In Vivo Drug Screening by Orthotopic Transplantation

Cells (Basel, Switzerland), 2023-12, Vol.13 (1), p.82

2023

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Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM + and CD90 + Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model

Cancers, 2022-04, Vol.14 (8), p.1882

2022

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Distinct functions of AKT isoforms in breast cancer: a comprehensive review

The Role of mTOR Signaling as a Therapeutic Target in Cancer

The Functional Role of Extracellular Matrix Proteins in Cancer

The Role of PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma Metabolism

The Functional Roles of the Src Homology 2 Domain-Containing Inositol 5-Phosphatases SHIP1 and SHIP2 in the Pathogenesis of Human Diseases

Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia

AKT in Bone Metastasis of Solid Tumors: A Comprehensive Review

Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects

Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells

Combined targeting of AKT and mTOR using MK‐2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma

Tight Junction Proteins Claudin-1 and Occludin Are Important for Cutaneous Wound Healing

Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells

Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4

All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines

Differential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer

Combined Targeting of AKT and mTOR Inhibits Proliferation of Human NF1-Associated Malignant Peripheral Nerve Sheath Tumour Cells In Vitro but not in a Xenograft Mouse Model In Vivo

Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway

Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors

Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic Acid-induced 2

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer

Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis

Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia

Generating Patient-Derived HCC Cell Lines Suitable for Predictive In Vitro and In Vivo Drug Screening by Orthotopic Transplantation

Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM + and CD90 + Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model

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