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IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation

The New England journal of medicine, 2017-08, Vol.377 (5), p.442-453

2017

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Imlifidase-generated Single-cleaved IgG: Implications for Transplantation

Transplantation, 2022-07, Vol.106 (7), p.1485-1496

2022

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The Bacterial Enzyme IdeS Cleaves the IgG-Type of B Cell Receptor (BCR), Abolishes BCR-Mediated Cell Signaling, and Inhibits Memory B Cell Activation

The Journal of immunology (1950), 2015-12, Vol.195 (12), p.5592-5601

2015

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Administration of immunoglobulin G‐degrading enzyme of Streptococcus pyogenes (IdeS) for persistent anti‐ADAMTS13 antibodies in patients with thrombotic thrombocytopenic purpura in clinical remission

British journal of haematology, 2019-07, Vol.186 (1), p.137-140

2019

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Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti‐HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients

American journal of transplantation, 2018-11, Vol.18 (11), p.2752-2762

2018

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Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS--A Novel Therapeutic Opportunity

PloS one, 2015-07, Vol.10 (7), p.e0132011-e0132011

2015

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Enzymatic Inactivation of Endogenous IgG by IdeS Enhances Therapeutic Antibody Efficacy

Molecular cancer therapeutics, 2017-09, Vol.16 (9), p.1887-1897

2017

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Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS

Molecular & cellular proteomics, 2018-06, Vol.17 (6), p.1097-1111

2018

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Alloantibody Levels, Immunoglobulin Degradation Products, and Platelet Transfusion Response over Successful Desensitization of Severe Alloimmune Platelet Refractoriness with a Novel IgG-Targeted Enzyme Therapeutic

Blood, 2023-11, Vol.142 (Supplement 1), p.2662-2662

2023

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IgG-degrading enzyme of Streptococcus pyogenes (IdeS) prevents disease progression and facilitates improvement in a rabbit model of Guillain-Barré syndrome

Experimental neurology, 2017-05, Vol.291, p.134-140

2017

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Identification of genes differentially expressed in TLS‐CHOP carrying myxoid liposarcomas

International journal of cancer, 1999-09, Vol.83 (1), p.30-33

1999

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Administration of immunoglobulin G‐degrading enzyme of Streptococcus pyogenes (IdeS) for persistent anti‐ ADAMTS 13 antibodies in patients with thrombotic thrombocytopenic purpura in clinical remission

British journal of haematology, 2019-07, Vol.186 (1), p.137-140

2019

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α 10 Integrin Expression Is Up-Regulated on Fibroblast Growth Factor-2-Treated Mesenchymal Stem Cells with Improved Chondrogenic Differentiation Potential

Stem cells and development, 2007-12, Vol.16 (6), p.965-978

2007

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HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo

Oncotarget, 2016-01, Vol.7 (1), p.433-445

2016

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The myxoid liposarcoma specific TLS‐CHOP fusion protein localizes to nuclear structures distinct from PML nuclear bodies

International journal of cancer, 2002-02, Vol.97 (4), p.446-450

2002

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The Myxoid/Round Cell Liposarcoma Fusion Oncogene FUS-DDIT3 and the Normal DDIT3 Induce a Liposarcoma Phenotype in Transfected Human Fibrosarcoma Cells

The American journal of pathology, 2006-05, Vol.168 (5), p.1642-1653

2006

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LEPREL1, a novel ER and Golgi resident member of the Leprecan family

Biochemical and biophysical research communications, 2004-04, Vol.317 (2), p.342-351

2004

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Combretastatin A‐1 phosphate potentiates the antitumor activity of carboplatin and paclitaxel in a severe combined immunodeficiency disease (SCID) mouse model of human ovarian carcinoma

International journal of gynecological cancer, 2006-07, Vol.16 (4), p.1557-1564

2006

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Alpha10 integrin expression is up-regulated on fibroblast growth factor-2-treated mesenchymal stem cells with improved chondrogenic differentiation potential

Stem cells and development, 2007-12, Vol.16 (6), p.965

2007

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Identification and characterization of a human smad3 splicing variant lacking part of the linker region

Gene, 2004-03, Vol.327 (2), p.141-152

2004

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Oncostatin M signaling in human glioma cell lines

Oncology reports, 2005-05, Vol.13 (5), p.807

2005

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Culturing of human tumor cells for use in immune gene tumor therapy

World Federation of Neuro-Oncology Second Quadrennial Meeting and the Sixth Meeting of the European Association for Neuro-Oncology,Edinburgh, United Kingdom,2005-05-05 - 2005-05-08, 2005, Vol.7 (3), p.371

2005

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Molecular studies of genetic changes in myxoid and round cell liposarcomas

Thelin-Jarnum, Sofia

2002

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IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation

Imlifidase-generated Single-cleaved IgG: Implications for Transplantation

The Bacterial Enzyme IdeS Cleaves the IgG-Type of B Cell Receptor (BCR), Abolishes BCR-Mediated Cell Signaling, and Inhibits Memory B Cell Activation

Administration of immunoglobulin G‐degrading enzyme of Streptococcus pyogenes (IdeS) for persistent anti‐ADAMTS13 antibodies in patients with thrombotic thrombocytopenic purpura in clinical remission

Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti‐HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients

Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS--A Novel Therapeutic Opportunity

Enzymatic Inactivation of Endogenous IgG by IdeS Enhances Therapeutic Antibody Efficacy

Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS

Alloantibody Levels, Immunoglobulin Degradation Products, and Platelet Transfusion Response over Successful Desensitization of Severe Alloimmune Platelet Refractoriness with a Novel IgG-Targeted Enzyme Therapeutic

IgG-degrading enzyme of Streptococcus pyogenes (IdeS) prevents disease progression and facilitates improvement in a rabbit model of Guillain-Barré syndrome

Identification of genes differentially expressed in TLS‐CHOP carrying myxoid liposarcomas

Administration of immunoglobulin G‐degrading enzyme of Streptococcus pyogenes (IdeS) for persistent anti‐ ADAMTS 13 antibodies in patients with thrombotic thrombocytopenic purpura in clinical remission

α 10 Integrin Expression Is Up-Regulated on Fibroblast Growth Factor-2-Treated Mesenchymal Stem Cells with Improved Chondrogenic Differentiation Potential

HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo

The myxoid liposarcoma specific TLS‐CHOP fusion protein localizes to nuclear structures distinct from PML nuclear bodies

The Myxoid/Round Cell Liposarcoma Fusion Oncogene FUS-DDIT3 and the Normal DDIT3 Induce a Liposarcoma Phenotype in Transfected Human Fibrosarcoma Cells

LEPREL1, a novel ER and Golgi resident member of the Leprecan family

Combretastatin A‐1 phosphate potentiates the antitumor activity of carboplatin and paclitaxel in a severe combined immunodeficiency disease (SCID) mouse model of human ovarian carcinoma

Alpha10 integrin expression is up-regulated on fibroblast growth factor-2-treated mesenchymal stem cells with improved chondrogenic differentiation potential

Identification and characterization of a human smad3 splicing variant lacking part of the linker region

Oncostatin M signaling in human glioma cell lines

Culturing of human tumor cells for use in immune gene tumor therapy

Molecular studies of genetic changes in myxoid and round cell liposarcomas

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