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Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease

The journal of prevention of Alzheimer's disease, 2022, Vol.9 (2), p.197-210

2022

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Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer's disease

Nature communications, 2022-08, Vol.13 (1), p.4566-15, Article 4566

2022

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Usability of a Web-Based Registry for Preclinical Alzheimer’s Disease: Implications from a Cross-Sectional Online Survey

The journal of prevention of Alzheimer's disease, 2024, Vol.11 (3), p.661-671

2024

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Tauroursodeoxycholic Acid Attenuates Diet-Induced and Age-Related Peripheral Endoplasmic Reticulum Stress and Cerebral Amyloid Pathology in a Mouse Model of Alzheimer’s Disease

The journal of prevention of Alzheimer's disease, 2021, Vol.8 (4), p.483-494

2021

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Molecular pathology to disease modification of Alzheimer's disease

Journal of the neurological sciences, 2019-10, Vol.405, p.17-18

Iwatsubo, T.

2019

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Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin

Oncogene, 2012-02, Vol.31 (6), p.787-798

2012

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Therapeutic Targets for Alzheimer’s Disease: Amyloid Vs. Non-Amyloid. Where Does Consensus Lie Today? An CTAD Task Force Report

The journal of prevention of Alzheimer's disease, 2022, Vol.9 (2), p.231-235

2022

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Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease

Molecular psychiatry, 2009-11, Vol.14 (11), p.1004-1016

2009

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Cohort-Specific Optimization of Models Predicting Preclinical Alzheimer’s Disease, to Enhance Screening Performance in the Middle of Preclinical Alzheimer’s Disease Clinical Studies

The journal of prevention of Alzheimer's disease, 2021, Vol.8 (4), p.503-512

2021

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Visual-statistical interpretation of (18)F-FDG-PET images for characteristic Alzheimer patterns in a multicenter study: inter-rater concordance and relationship to automated quantitative evaluation

American journal of neuroradiology : AJNR, 2014-02, Vol.35 (2), p.244

2014

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Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

Pharmacological reviews, 1998-09, Vol.50 (3), p.387

1998

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Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies

The American journal of pathology, 1998-04, Vol.152 (4), p.879-884

1998

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Peripheral Blood BRCA1 Methylation Positively Correlates with Major Alzheimer’s Disease Risk Factors

The journal of prevention of Alzheimer's disease, 2021, Vol.8 (4), p.477-482

2021

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Editorial: Clinical Implementation of Lecanemab: Challenges, Questions and Solutions

The journal of prevention of Alzheimer's disease, 2023, Vol.10 (3), p.353-355

Iwatsubo, T

2023

Volltextzugriff (PDF)

Clinical Implementation of Lecanemab: Challenges, Questions and Solutions

The journal of prevention of Alzheimer's disease, 2023-09, Vol.10 (3), p.353-355

Iwatsubo, Takeshi

2023

Volltextzugriff (PDF)

Using Digital Tools to Advance Alzheimer’s Drug Trials During a Pandemic: The EU/US CTAD Task Force

The journal of prevention of Alzheimer's disease, 2021, Vol.8 (4), p.513-519

2021

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Functional involvement of organic cation transporter1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats

Xenobiotica, 2007-08, Vol.37 (8), p.818-831

2007

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Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab

The journal of prevention of Alzheimer's disease, 2023, Vol.10 (2), p.171-177

2023

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Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

Annual review of pharmacology and toxicology, 1998-01, Vol.38 (1), p.461-499

1998

Volltextzugriff (PDF)

Longitudinal study of cerebrospinal fluid levels of tau, Aβ1-40, and Aβ1-42(43) in Alzheimer's disease: A study in Japan

Annals of neurology, 1998-07, Vol.44 (1), p.17-26

1998

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Investigation of a colloidal damper

Journal of colloid and interface science, 2003-03, Vol.259 (1), p.62-80

2003

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Novel and global approach of the complex and interconnected phenomena related to the contact line movement past a solid surface from hydrophobized silica gel

Journal of colloid and interface science, 2005-03, Vol.283 (1), p.196-214

2005

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The Amyloid-β Pathway in Alzheimer's Disease

Molecular psychiatry, 2021-10, Vol.26 (10), p.5481-5503

2021

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Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer’s disease

Journal of neurology, neurosurgery and psychiatry, 2004-07, Vol.75 (7), p.1039-1042

2004

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The γ-secretase complex: machinery for intramembrane proteolysis

Current opinion in neurobiology, 2004-06, Vol.14 (3), p.379-383

Iwatsubo, Takeshi

2004

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Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease

Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer's disease

Usability of a Web-Based Registry for Preclinical Alzheimer’s Disease: Implications from a Cross-Sectional Online Survey

Tauroursodeoxycholic Acid Attenuates Diet-Induced and Age-Related Peripheral Endoplasmic Reticulum Stress and Cerebral Amyloid Pathology in a Mouse Model of Alzheimer’s Disease

Molecular pathology to disease modification of Alzheimer's disease

Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin

Therapeutic Targets for Alzheimer’s Disease: Amyloid Vs. Non-Amyloid. Where Does Consensus Lie Today? An CTAD Task Force Report

Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease

Cohort-Specific Optimization of Models Predicting Preclinical Alzheimer’s Disease, to Enhance Screening Performance in the Middle of Preclinical Alzheimer’s Disease Clinical Studies

Visual-statistical interpretation of (18)F-FDG-PET images for characteristic Alzheimer patterns in a multicenter study: inter-rater concordance and relationship to automated quantitative evaluation

Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies

Peripheral Blood BRCA1 Methylation Positively Correlates with Major Alzheimer’s Disease Risk Factors

Editorial: Clinical Implementation of Lecanemab: Challenges, Questions and Solutions

Clinical Implementation of Lecanemab: Challenges, Questions and Solutions

Using Digital Tools to Advance Alzheimer’s Drug Trials During a Pandemic: The EU/US CTAD Task Force

Functional involvement of organic cation transporter1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats

Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab

Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

Longitudinal study of cerebrospinal fluid levels of tau, Aβ1-40, and Aβ1-42(43) in Alzheimer's disease: A study in Japan

Investigation of a colloidal damper

Novel and global approach of the complex and interconnected phenomena related to the contact line movement past a solid surface from hydrophobized silica gel

The Amyloid-β Pathway in Alzheimer's Disease

Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer’s disease

The γ-secretase complex: machinery for intramembrane proteolysis

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