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The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections

PLoS neglected tropical diseases, 2022-03, Vol.16 (3), p.e0010220-e0010220

2022

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Eastern equine encephalitis virus rapidly infects and disseminates in the brain and spinal cord of cynomolgus macaques following aerosol challenge

PLoS neglected tropical diseases, 2022-05, Vol.16 (5), p.e0010081-e0010081

2022

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Advanced antisense therapies for postexposure protection against lethal filovirus infections

Nature medicine, 2010-09, Vol.16 (9), p.991-994

2010

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Molecular Basis of Resilience: Adapting to a Changing Environment

Iversen, Patrick L

1st ed. 2018., 2018

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Sustained Dystrophin Expression Induced by Peptide-conjugated Morpholino Oligomers in the Muscles of mdx Mice

Molecular therapy, 2008-09, Vol.16 (9), p.1624-1629

2008

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Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum

Human molecular genetics, 2011-08, Vol.20 (16), p.3151-3160

2011

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Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (39), p.14814-14819

2008

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Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections

Viruses, 2012-11, Vol.4 (11), p.2806-2830

2012

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Inactivated COVID-19 vaccines to make a global impact

The Lancet infectious diseases, 2021-06, Vol.21 (6), p.746-748

2021

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Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus

Scientific reports, 2021-09, Vol.11 (1), p.19458-19458, Article 19458

2021

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Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

PloS one, 2014-02, Vol.9 (2), p.e88726

2014

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Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques

PLoS neglected tropical diseases, 2016-02, Vol.10 (2), p.e0004456-e0004456

2016

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A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection

mBio, 2015-02, Vol.6 (1)

2015

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Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease

Scientific reports, 2021-02, Vol.11 (1), p.4722-20, Article 4722

2021

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Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide−Morpholino Oligomer Conjugate

Bioconjugate chemistry, 2007-07, Vol.18 (4), p.1325-1331

2007

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Author Correction: Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease

Scientific reports, 2021-05, Vol.11 (1), p.10711-1, Article 10711

2021

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Vectorization of morpholino oligomers by the (R-Ahx-R) 4 peptide allows efficient splicing correction in the absence of endosomolytic agents

Journal of controlled release, 2006-12, Vol.116 (3), p.304-313

2006

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A novel therapeutic vaccine targeting the soluble TNFα receptor II to limit the progression of cardiovascular disease: AtheroVax

Frontiers in cardiovascular medicine, 2023-07, Vol.10, p.1206541-1206541

2023

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Is there space for a three-dose vaccine to fight the spread of SARS-CoV-2?

The Lancet infectious diseases, 2021-08, Vol.21 (8), p.1054-1055

2021

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West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions

Virology (New York, N.Y.), 2008-03, Vol.373 (1), p.1-13

2008

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Antisense Phosphorodiamidate Morpholino Oligomers Targeted to an Essential Gene Inhibit Burkholderia cepacia Complex

The Journal of infectious diseases, 2010-06, Vol.201 (12), p.1822-1830

2010

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Bacterial Resistance to Antisense Peptide Phosphorodiamidate Morpholino Oligomers

Antimicrobial Agents and Chemotherapy, 2012-12, Vol.56 (12), p.6147-6153

2012

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Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3′ stem–loop structure

Virology (New York, N.Y.), 2006-01, Vol.344 (2), p.439-452

2006

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Variations in Amino Acid Composition of Antisense Peptide-Phosphorodiamidate Morpholino Oligomer Affect Potency against Escherichia coli In Vitro and In Vivo

Antimicrobial Agents and Chemotherapy, 2009-02, Vol.53 (2), p.525-530

2009

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Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers

PLoS computational biology, 2006-01, Vol.2 (1), p.e1-e1

2006

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The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections

Eastern equine encephalitis virus rapidly infects and disseminates in the brain and spinal cord of cynomolgus macaques following aerosol challenge

Advanced antisense therapies for postexposure protection against lethal filovirus infections

Molecular Basis of Resilience: Adapting to a Changing Environment

Sustained Dystrophin Expression Induced by Peptide-conjugated Morpholino Oligomers in the Muscles of mdx Mice

Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections

Inactivated COVID-19 vaccines to make a global impact

Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus

Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques

A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection

Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease

Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide−Morpholino Oligomer Conjugate

Author Correction: Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease

Vectorization of morpholino oligomers by the (R-Ahx-R) 4 peptide allows efficient splicing correction in the absence of endosomolytic agents

A novel therapeutic vaccine targeting the soluble TNFα receptor II to limit the progression of cardiovascular disease: AtheroVax

Is there space for a three-dose vaccine to fight the spread of SARS-CoV-2?

West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions

Antisense Phosphorodiamidate Morpholino Oligomers Targeted to an Essential Gene Inhibit Burkholderia cepacia Complex

Bacterial Resistance to Antisense Peptide Phosphorodiamidate Morpholino Oligomers

Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3′ stem–loop structure

Variations in Amino Acid Composition of Antisense Peptide-Phosphorodiamidate Morpholino Oligomer Affect Potency against Escherichia coli In Vitro and In Vivo

Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers

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