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The war against influenza: discovery and development of sialidase inhibitors

Nature reviews. Drug discovery, 2007-12, Vol.6 (12), p.967-974

von Itzstein, Mark

2007

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Conformational Modulation of Iduronic Acid‐Containing Sulfated Glycosaminoglycans by a Polynuclear Platinum Compound and Implications for Development of Antimetastatic Platinum Drugs

Angewandte Chemie International Edition, 2021-02, Vol.60 (6), p.3283-3289

International ed. in English, 2021

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How Size Matters: Diversity for Fragment Library Design

Molecules (Basel, Switzerland), 2019-08, Vol.24 (15), p.2838

2019

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Neutralizing the pathological effects of extracellular histones with small polyanions

Nature communications, 2020-12, Vol.11 (1), p.6408-17, Article 6408

2020

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Glycointeractions in bacterial pathogenesis

Nature reviews. Microbiology, 2018-07, Vol.16 (7), p.440-452

2018

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Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice

Nature communications, 2015-08, Vol.6 (1), p.8141-8141, Article 8141

2015

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Approach for Profiling of Glycosphingolipid Glycosylation by Multiplexed Capillary Gel Electrophoresis Coupled to Laser-Induced Fluorescence Detection To Identify Cell-Surface Markers of Human Pluripotent Stem Cells and Derived Cardiomyocytes

Analytical chemistry (Washington), 2019-05, Vol.91 (10), p.6413-6418

2019

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Limited Inhibitory Effects of Oseltamivir and Zanamivir on Human Sialidases

Antimicrobial Agents and Chemotherapy, 2008-10, Vol.52 (10), p.3484-3491

2008

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NAD + cleavage activity by animal and plant TIR domains in cell death pathways

Science (American Association for the Advancement of Science), 2019-08, Vol.365 (6455), p.793-799

2019

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Binding of a natural anthocyanin inhibitor to influenza neuraminidase by mass spectrometry

Analytical and bioanalytical chemistry, 2013-08, Vol.405 (20), p.6563-6572

2013

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Microbial glycobiology: structures, relevance and applications

1, 2009

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The Catalytic Mechanism of Human Parainfluenza Virus Type 3 Haemagglutinin-Neuraminidase Revealed

Angewandte Chemie International Edition, 2015-03, Vol.54 (10), p.2936-2940

2015

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Specificity and affinity of neuraminic acid exhibited by canine rotavirus strain K9 carbohydrate‐binding domain (VP8)

Journal of molecular recognition, 2018-09, Vol.31 (9), p.e2718-n/a

2018

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The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design

Scientific reports, 2017-07, Vol.7 (1), p.4507-10, Article 4507

2017

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A Sulfonozanamivir Analogue Has Potent Anti‐influenza Virus Activity

ChemMedChem, 2018-04, Vol.13 (8), p.785-789

2018

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C-4 Modified Sialosides Enhance Binding to Siglec-2 (CD22): Towards Potent Siglec Inhibitors for Immunoglycotherapy

Angewandte Chemie International Edition, 2013-03, Vol.52 (13), p.3616-3620

International ed. in English, 2013

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Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin

Pharmaceuticals (Basel, Switzerland), 2021-12, Vol.15 (1), p.26

2021

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Platinum complexes act as shielding agents against virus infection

Chemical communications (Cambridge, England), 2021-05, Vol.57 (38), p.4666-4669

2021

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Structural Basis of Rotavirus Strain Preference toward N-Acetyl- or N-Glycolylneuraminic Acid-Containing Receptors

Journal of Virology, 2012-12, Vol.86 (24), p.13456-13466

2012

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The mechanism of the first step of the Mitsunobu reaction

Tetrahedron, 2015-07, Vol.71 (30), p.4946-4948

2015

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Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Receptor Interactions

mBio, 2021-03, Vol.12 (2)

2021

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Anti-influenza drugs: the development of sialidase inhibitors

Handbook of experimental pharmacology, 2009 (189), p.111

2009

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Novel 3,4-disubstituted-Neu5Ac2en derivatives as probes to investigate flexibility of the influenza virus sialidase 150-loop

Bioorganic & medicinal chemistry, 2013-08, Vol.21 (16), p.4820-4830

2013

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Enhancing Vaccine Efficacy by Engineering a Complex Synthetic Peptide To Become a Super Immunogen

The Journal of immunology (1950), 2017-10, Vol.199 (8), p.2794-2802

2017

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The war against influenza: discovery and development of sialidase inhibitors

Conformational Modulation of Iduronic Acid‐Containing Sulfated Glycosaminoglycans by a Polynuclear Platinum Compound and Implications for Development of Antimetastatic Platinum Drugs

How Size Matters: Diversity for Fragment Library Design

Neutralizing the pathological effects of extracellular histones with small polyanions

Glycointeractions in bacterial pathogenesis

Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice

Approach for Profiling of Glycosphingolipid Glycosylation by Multiplexed Capillary Gel Electrophoresis Coupled to Laser-Induced Fluorescence Detection To Identify Cell-Surface Markers of Human Pluripotent Stem Cells and Derived Cardiomyocytes

Limited Inhibitory Effects of Oseltamivir and Zanamivir on Human Sialidases

NAD + cleavage activity by animal and plant TIR domains in cell death pathways

Binding of a natural anthocyanin inhibitor to influenza neuraminidase by mass spectrometry

Microbial glycobiology: structures, relevance and applications

Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria‐related pathways in colorectal cancer

The Catalytic Mechanism of Human Parainfluenza Virus Type 3 Haemagglutinin-Neuraminidase Revealed

Specificity and affinity of neuraminic acid exhibited by canine rotavirus strain K9 carbohydrate‐binding domain (VP8)

The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design

A Sulfonozanamivir Analogue Has Potent Anti‐influenza Virus Activity

C-4 Modified Sialosides Enhance Binding to Siglec-2 (CD22): Towards Potent Siglec Inhibitors for Immunoglycotherapy

Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin

Platinum complexes act as shielding agents against virus infection

Structural Basis of Rotavirus Strain Preference toward N-Acetyl- or N-Glycolylneuraminic Acid-Containing Receptors

The mechanism of the first step of the Mitsunobu reaction

Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Receptor Interactions

Anti-influenza drugs: the development of sialidase inhibitors

Novel 3,4-disubstituted-Neu5Ac2en derivatives as probes to investigate flexibility of the influenza virus sialidase 150-loop

Enhancing Vaccine Efficacy by Engineering a Complex Synthetic Peptide To Become a Super Immunogen

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