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Motilin and Clinical Application

Peptides, 1997, Vol.18 (4), p.593-608

Itoh, Zen

1997

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Mitemcinal (GM‐611), an orally active motilin agonist, facilitates defecation in rabbits and dogs without causing loose stools

Neurogastroenterology and motility, 2007-04, Vol.19 (4), p.318-326

2007

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Ghrelin Stimulates Gastric Acid Secretion and Motility in Rats

Biochemical and biophysical research communications, 2000-10, Vol.276 (3), p.905-908

2000

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AS-4370, a new gastrokinetic agent, enhances upper gastrointestinal motor activity in conscious dogs

The Journal of pharmacology and experimental therapeutics, 1991-05, Vol.257 (2), p.781

1991

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Mitemcinal (GM-611), an orally active motilin receptor agonist, accelerates colonic motility and bowel movement in conscious dogs

Inflammopharmacology, 2007-02, Vol.15 (1), p.36-42

2007

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Erythromycin improves glycaemic control in patients with Type II diabetes mellitus

Diabetologia, 2000-04, Vol.43 (4), p.411-415

2000

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Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride

The Journal of pharmacology and experimental therapeutics, 2011-03, Vol.336 (3), p.791-800

2011

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Motilin is a biosignal controlling cyclic release of pancreatic polypeptide via the vagus in fasted dogs

American journal of physiology: Gastrointestinal and liver physiology, 1997-02, Vol.272 (2 Pt 1), p.G224-G232

1997

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Initiation of phase III contractions in the jejunum by atropine, hexamethonium and xylocaine in conscious dogs

Neurogastroenterology and motility, 2000-02, Vol.12 (1), p.11-21

2000

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Erythromycin mimics exogenous motilin in gastrointestinal contractile activity in the dog

American journal of physiology: Gastrointestinal and liver physiology, 1984-12, Vol.10 (6), p.G688-G694

1984

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Erythromycin induces migrating motor complex in human gastrointestinal tract

Digestive diseases and sciences, 1986-02, Vol.31 (2), p.157-161

1986

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Gastroprokinetic activity of nizatidine, a new H2-receptor antagonist, and its possible mechanism of action in dogs and rats

The Journal of pharmacology and experimental therapeutics, 1993-01, Vol.264 (1), p.152

1993

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Role of endogenous 5-hydroxytryptamine in the regulation of gastric contractions by motilin in dogs

American journal of physiology: Gastrointestinal and liver physiology, 1996-01, Vol.270 (1 Pt 1), p.G20-G28

1996

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An erythromycin derivative, EM-523, induces motilin-like gastrointestinal motility in dogs

The Journal of pharmacology and experimental therapeutics, 1989-11, Vol.251 (2), p.707

1989

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EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrum

The Journal of pharmacology and experimental therapeutics, 1994-10, Vol.271 (1), p.574

1994

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Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs

Gastroenterology (New York, N.Y. 1943), 1996-01, Vol.110 (1), p.241-250

1996

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Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs

The Journal of pharmacology and experimental therapeutics, 1991-01, Vol.256 (1), p.272

1991

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Prostaglandin E2 stimulates motilin release via a cholinergic muscarinic pathway in the dog

Neurogastroenterology and motility, 2000-12, Vol.12 (6), p.523-530

2000

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Effect of 5‐hydroxytryptamine on gastrointestinal motility in conscious guinea‐pigs

Neurogastroenterology and motility, 1997-12, Vol.9 (4), p.205-214

1997

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A new method to measure gastric emptying in conscious dogs: a validity study and effects of EM523 and L-NNA

American journal of physiology: Gastrointestinal and liver physiology, 1997-04, Vol.272 (4 Pt 1), p.G909-G915

1997

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Exogenous motilin stimulates endogenous release of motilin through cholinergic muscarinic pathways in the dog

Gastroenterology (New York, N.Y. 1943), 1996-12, Vol.111 (6), p.1456-1464

1996

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Gastrointestinal motor-stimulating activity of macrolide antibiotics and analysis of their side effects on the canine gut

Antimicrobial Agents and Chemotherapy, 1984-12, Vol.26 (6), p.863-869

1984

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Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans

Digestive diseases and sciences, 1993-05, Vol.38 (5), p.870-876

1993

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Effect of truncal vagotomy on gallbladder bile kinetics in conscious dogs

Neurogastroenterology and motility, 1999-10, Vol.11 (5), p.357-364

1999

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EM-523, an erythromycin derivative, and motilin show similar contractile activity in isolated rabbit intestine

The Journal of pharmacology and experimental therapeutics, 1990-09, Vol.254 (3), p.940

1990

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Motilin and Clinical Application

Mitemcinal (GM‐611), an orally active motilin agonist, facilitates defecation in rabbits and dogs without causing loose stools

Ghrelin Stimulates Gastric Acid Secretion and Motility in Rats

AS-4370, a new gastrokinetic agent, enhances upper gastrointestinal motor activity in conscious dogs

Mitemcinal (GM-611), an orally active motilin receptor agonist, accelerates colonic motility and bowel movement in conscious dogs

Erythromycin improves glycaemic control in patients with Type II diabetes mellitus

Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride

Motilin is a biosignal controlling cyclic release of pancreatic polypeptide via the vagus in fasted dogs

Initiation of phase III contractions in the jejunum by atropine, hexamethonium and xylocaine in conscious dogs

Erythromycin mimics exogenous motilin in gastrointestinal contractile activity in the dog

Erythromycin induces migrating motor complex in human gastrointestinal tract

Gastroprokinetic activity of nizatidine, a new H2-receptor antagonist, and its possible mechanism of action in dogs and rats

Role of endogenous 5-hydroxytryptamine in the regulation of gastric contractions by motilin in dogs

An erythromycin derivative, EM-523, induces motilin-like gastrointestinal motility in dogs

EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrum

Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs

Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs

Prostaglandin E2 stimulates motilin release via a cholinergic muscarinic pathway in the dog

Effect of 5‐hydroxytryptamine on gastrointestinal motility in conscious guinea‐pigs

A new method to measure gastric emptying in conscious dogs: a validity study and effects of EM523 and L-NNA

Exogenous motilin stimulates endogenous release of motilin through cholinergic muscarinic pathways in the dog

Gastrointestinal motor-stimulating activity of macrolide antibiotics and analysis of their side effects on the canine gut

Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans

Effect of truncal vagotomy on gallbladder bile kinetics in conscious dogs

EM-523, an erythromycin derivative, and motilin show similar contractile activity in isolated rabbit intestine

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