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Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine

Journal of lipid research, 2006-06, Vol.47 (6), p.1281-1288

2006

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Pharmacological regulation of low density lipoprotein receptor expression: current status and future developments

Pharmacology & therapeutics (Oxford), 2006-08, Vol.111 (2), p.424-433

Issandou, Marc

2006

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Liver X receptor activation promotes macrophage-to-feces reverse cholesterol transport in a dyslipidemic hamster model

Journal of lipid research, 2010-04, Vol.51 (4), p.763-770

2010

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Pharmacological inhibition of Stearoyl-CoA Desaturase 1 improves insulin sensitivity in insulin-resistant rat models

European journal of pharmacology, 2009-09, Vol.618 (1), p.28-36

2009

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The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking

Journal of lipid research, 2004-02, Vol.45 (2), p.223-231

2004

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SCAP ligands are potent new lipid-lowering drugs

Nature medicine, 2001-12, Vol.7 (12), p.1332-1338

2001

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Selective CETP Inhibition and PPARα Agonism Increase HDL Cholesterol and Reduce LDL Cholesterol in Human ApoB100/Human CETP Transgenic Mice

Journal of cardiovascular pharmacology and therapeutics, 2010-06, Vol.15 (2), p.196-202

2010

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The imidazoline-like drug S23515 affects lipid metabolism in hepatocyte by inhibiting the oxidosqualene:lanosterol cyclase activity

Biochemical pharmacology, 2005-04, Vol.69 (7), p.1041-1048

2005

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Multidrug Resistance P-Glycoprotein Is Not Involved in Cholesterol Esterification

Biochemical and biophysical research communications, 2000-12, Vol.279 (2), p.369-377

2000

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Up-regulation of low-density lipoprotein receptor in human hepatocytes is induced by sequestration of free cholesterol in the endosomal/lysosomal compartment

Biochemical pharmacology, 2004-06, Vol.67 (12), p.2281-2289

2004

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Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity

Bioorganic & medicinal chemistry, 2008-06, Vol.16 (11), p.6218-6232

2008

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Selective CETP Inhibition and PPARa Agonism Increase HDL Cholesterol and Reduce LDL Cholesterol in Human ApoB100/Human CETP Transgenic Mice

Journal of cardiovascular pharmacology and therapeutics, 2010-06, Vol.15 (2), p.196-202

2010

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Basic Fibroblast Growth Factor Stimulates Glomerular Mesangial Cell Proliferation Through a Protein Kinase C-Independent Pathway

Growth factors (Chur, Switzerland), 1991, Vol.5 (4), p.255-264

1991

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Bradykinin transiently activates protein kinase C in Swiss 3T3 cells. Distinction from activation by bombesin and vasopressin

The Journal of biological chemistry, 1990-07, Vol.265 (20), p.11890-11896

1990

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Selective CETP inhibition and PPARalpha agonism increase HDL cholesterol and reduce LDL cholesterol in human ApoB100/human CETP transgenic mice

Journal of cardiovascular pharmacology and therapeutics, 2010-06, Vol.15 (2), p.196-202

2010

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Une nouvelle classe de molécules hypolipémiantes : les ligands de SCAP

M.S. Médecine sciences, 2002-06, Vol.18 (6-7), p.659-661

2002

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Une nouvelle classe de molécules hypolipémiantes : les ligands de SCAP

M.S. Médecine sciences, 2002-06, Vol.18 (6-7), p.659-661

2002

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Une nouvelle classe de molécules hypolipémiantes: les lignads de SCAP

M.S. Médecine sciences, 2002, Vol.18 (6-7), p.659-661

2002

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Retinoids stimulate fibrinogen production both in vitro (hepatocytes) and in vivo. Induction requires activation of the retinoid X receptor

Arteriosclerosis, thrombosis, and vascular biology, 1995-10, Vol.15 (10), p.1660

1995

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Inhibition of MCF-7 cell growth by 12-O-tetradecanoylphorbol-13-acetate and 1,2-dioctanoyl-sn-glycerol: distinct effects on protein kinase C activity

Cancer research (Chicago, Ill.), 1988-12, Vol.48 (23), p.6943

1988

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Activation of protein kinase C by phorbol esters induces DNA synthesis and protein phosphorylations in glomerular mesangial cells

FEBS letters, 1991-04, Vol.281 (1), p.196-200

1991

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1,2-Dioctanoyl-glycerol induces a discrete but transient translocation of protein kinase C as well as the inhibition of MCF-7 cell proliferation

Biochemical and biophysical research communications, 1988-02, Vol.151 (1), p.458-465

1988

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Dissociation between protein kinase C content and biological responsiveness to phorbol esters in tumor promoter-sensitive (MCF-7) and resistant (RPh-4) cells

Biochemical pharmacology, 1990-10, Vol.40 (8), p.1785-1792

1990

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Activation by phorbol esters of protein kinase C in MCF-7 human breast cancer cells

FEBS letters, 1986-05, Vol.200 (2), p.337-342

1986

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The 27 K and 28 K protein kinase c substrates in endothelial and MCF-7 cells are stress proteins

Cell biology international reports, 1990-09, Vol.14, p.147-147

1990

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Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine

Pharmacological regulation of low density lipoprotein receptor expression: current status and future developments

Liver X receptor activation promotes macrophage-to-feces reverse cholesterol transport in a dyslipidemic hamster model

Pharmacological inhibition of Stearoyl-CoA Desaturase 1 improves insulin sensitivity in insulin-resistant rat models

The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking

SCAP ligands are potent new lipid-lowering drugs

Selective CETP Inhibition and PPARα Agonism Increase HDL Cholesterol and Reduce LDL Cholesterol in Human ApoB100/Human CETP Transgenic Mice

The imidazoline-like drug S23515 affects lipid metabolism in hepatocyte by inhibiting the oxidosqualene:lanosterol cyclase activity

Multidrug Resistance P-Glycoprotein Is Not Involved in Cholesterol Esterification

Up-regulation of low-density lipoprotein receptor in human hepatocytes is induced by sequestration of free cholesterol in the endosomal/lysosomal compartment

Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity

Selective CETP Inhibition and PPARa Agonism Increase HDL Cholesterol and Reduce LDL Cholesterol in Human ApoB100/Human CETP Transgenic Mice

Basic Fibroblast Growth Factor Stimulates Glomerular Mesangial Cell Proliferation Through a Protein Kinase C-Independent Pathway

Bradykinin transiently activates protein kinase C in Swiss 3T3 cells. Distinction from activation by bombesin and vasopressin

Selective CETP inhibition and PPARalpha agonism increase HDL cholesterol and reduce LDL cholesterol in human ApoB100/human CETP transgenic mice

Une nouvelle classe de molécules hypolipémiantes : les ligands de SCAP

Une nouvelle classe de molécules hypolipémiantes : les ligands de SCAP

Une nouvelle classe de molécules hypolipémiantes: les lignads de SCAP

Retinoids stimulate fibrinogen production both in vitro (hepatocytes) and in vivo. Induction requires activation of the retinoid X receptor

Inhibition of MCF-7 cell growth by 12-O-tetradecanoylphorbol-13-acetate and 1,2-dioctanoyl-sn-glycerol: distinct effects on protein kinase C activity

Activation of protein kinase C by phorbol esters induces DNA synthesis and protein phosphorylations in glomerular mesangial cells

1,2-Dioctanoyl-glycerol induces a discrete but transient translocation of protein kinase C as well as the inhibition of MCF-7 cell proliferation

Dissociation between protein kinase C content and biological responsiveness to phorbol esters in tumor promoter-sensitive (MCF-7) and resistant (RPh-4) cells

Activation by phorbol esters of protein kinase C in MCF-7 human breast cancer cells

The 27 K and 28 K protein kinase c substrates in endothelial and MCF-7 cells are stress proteins

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