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Altered expression of topoisomerase IIα contributes to cross- resistant to etoposide K562/MX2 cell line by aberrant methylation

British journal of cancer, 2005-04, Vol.92 (8), p.1486-1492

2005

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Transcriptional Up-regulation of Inhibitory PAS Domain Protein Gene Expression by Hypoxia-inducible Factor 1 (HIF-1): A NEGATIVE FEEDBACK REGULATORY CIRCUIT IN HIF-1-MEDIATED SIGNALING IN HYPOXIC CELLS

The Journal of biological chemistry, 2007-05, Vol.282 (19), p.14073-14082

2007

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Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Structure−Activity Relationships, and Antitumor Activities of N-Phenyl-N‘-{4-(4-quinolyloxy)phenyl}ureas

Journal of medicinal chemistry, 2005-03, Vol.48 (5), p.1359-1366

2005

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Inhibition of ubiquitin-ATP-dependent proteolysis and ubiquitination by cisplatin

Anticancer research, 1991-09, Vol.11 (5), p.1905

1991

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Synthesis and structure-activity relationship for new series of 4-phenoxyquinoline derivatives as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase

Bioorganic & medicinal chemistry, 2003-11, Vol.11 (23), p.5117-5133

2003

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Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody

Cancer research (Chicago, Ill.), 1990-11, Vol.50 (21), p.6925-6930

1990

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An open-label phase I dose escalation study of KRN951, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 and 1 in a 4 week on, 2 week off schedule in patients with advanced solid tumors

Journal of clinical oncology, 2006-06, Vol.24 (18_suppl), p.2034-2034

2006

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Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation

British journal of cancer, 2005-04, Vol.92 (8), p.1486

2005

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Altered expression of topoisomerase II contributes to cross-resistant to etoposide K562 MX2 cell line by aberrant methylation

British journal of cancer, 2005-04, Vol.92 (8), p.1486-1492

2005

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38 POSTER Phase I and pharmacological study of KRN951, a potent VEGFR tyrosine kinase inhibitor given in a 4 week on, 2 week off schedule in patients with advanced solid tumors

European journal of cancer supplements, 2006-11, Vol.4 (12), p.16-16

2006

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Gilvusmycin, a New Antitumor Antibiotic Related to CC-1065

The Journal of Antibiotics, 1999/03/25, Vol.52(3), pp.263-268

1999

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Suppression of experimental lung colonization of a metastatic variant of murine colon adenocarcinoma 26 by a monoclonal antibody 8F11 inhibiting tumor cell-induced platelet aggregation

Cancer research (Chicago, Ill.), 1991-02, Vol.51 (3), p.921-925

1991

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Selective Inhibition of Platelet-Derived Growth Factor (PDGF) Receptor Autophosphorylation and PDGF-Mediated Cellular Events by a Quinoline Derivative

Experimental cell research, 1997-08, Vol.234 (2), p.285-292

1997

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Cellular pharmacology of MX2, a new morpholino anthracycline, in human pleiotropic drug-resistant cells

Cancer research (Chicago, Ill.), 1991, Vol.51 (1), p.157-161

1991

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Inhibition of different steps of the ubiquitin system by cisplatin and aclarubicin

Biochimica et biophysica acta, 1992-09, Vol.1117 (2), p.131-135

1992

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Occupational Exposure Management at Nuclear Power Plants: Fourth ISOE European Symposium - Lyon, France 24-26 March 2004

1, 2005

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STRUCTURE-ANTITUMOR ACTIVITY RELATIONSHIP OF SEMI-SYNTHETIC SPICAMYCIN ANALOGUES

The Journal of Antibiotics, 1993/09/25, Vol.46(9), pp.1439-1446

1993

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Antitumor activity of a spicamycin derivative, KRN5500, and its active metabolite in tumor cells

Oncology research, 1994, Vol.6 (8), p.383

1994

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ANTITUMOR ACTIVITY OF SPM VIII, A DERIVATIVE OF THE NUCLEOSIDE ANTIBIOTIC SPICAMYCIN, AGAINST HUMAN TUMOR XENOGRAFTS

The Journal of Antibiotics, 1994/11/25, Vol.47(11), pp.1305-1311

1994

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HERP1 Is a Cell Type-specific Primary Target of Notch

The Journal of biological chemistry, 2002-02, Vol.277 (8), p.6598-6607

2002

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Identification and characterization of a mosquito-specific eggshell organizing factor in Aedes aegypti mosquitoes

PLoS biology, 2019-01, Vol.17 (1), p.e3000068-e3000068

2019

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Xanthine dehydrogenase‐1 silencing in Aedes aegypti mosquitoes promotes a blood feeding–induced adulticidal activity

The FASEB journal, 2017-06, Vol.31 (6), p.2276-2286

2017

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Clinical features of freezing of gait in Parkinson's disease patients

Brain and behavior, 2019-04, Vol.9 (4), p.e01244-n/a

2019

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Non‐ergot dopamine agonist therapy for Parkinson's disease in Japan: A claims database analysis

Neurology and clinical neuroscience, 2023-03, Vol.11 (2), p.63-71

2023

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Differences in Parkinson's disease treatment between neurology and other departments in Japan

Neurology and clinical neuroscience, 2023-03, Vol.11 (2), p.79-89

2023

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Altered expression of topoisomerase IIα contributes to cross- resistant to etoposide K562/MX2 cell line by aberrant methylation

Transcriptional Up-regulation of Inhibitory PAS Domain Protein Gene Expression by Hypoxia-inducible Factor 1 (HIF-1): A NEGATIVE FEEDBACK REGULATORY CIRCUIT IN HIF-1-MEDIATED SIGNALING IN HYPOXIC CELLS

Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Structure−Activity Relationships, and Antitumor Activities of N-Phenyl-N‘-{4-(4-quinolyloxy)phenyl}ureas

Inhibition of ubiquitin-ATP-dependent proteolysis and ubiquitination by cisplatin

Synthesis and structure-activity relationship for new series of 4-phenoxyquinoline derivatives as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase

Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody

An open-label phase I dose escalation study of KRN951, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 and 1 in a 4 week on, 2 week off schedule in patients with advanced solid tumors

Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation

Altered expression of topoisomerase II contributes to cross-resistant to etoposide K562 MX2 cell line by aberrant methylation

38 POSTER Phase I and pharmacological study of KRN951, a potent VEGFR tyrosine kinase inhibitor given in a 4 week on, 2 week off schedule in patients with advanced solid tumors

Gilvusmycin, a New Antitumor Antibiotic Related to CC-1065

Suppression of experimental lung colonization of a metastatic variant of murine colon adenocarcinoma 26 by a monoclonal antibody 8F11 inhibiting tumor cell-induced platelet aggregation

Selective Inhibition of Platelet-Derived Growth Factor (PDGF) Receptor Autophosphorylation and PDGF-Mediated Cellular Events by a Quinoline Derivative

Cellular pharmacology of MX2, a new morpholino anthracycline, in human pleiotropic drug-resistant cells

Inhibition of different steps of the ubiquitin system by cisplatin and aclarubicin

Occupational Exposure Management at Nuclear Power Plants: Fourth ISOE European Symposium - Lyon, France 24-26 March 2004

STRUCTURE-ANTITUMOR ACTIVITY RELATIONSHIP OF SEMI-SYNTHETIC SPICAMYCIN ANALOGUES

Antitumor activity of a spicamycin derivative, KRN5500, and its active metabolite in tumor cells

ANTITUMOR ACTIVITY OF SPM VIII, A DERIVATIVE OF THE NUCLEOSIDE ANTIBIOTIC SPICAMYCIN, AGAINST HUMAN TUMOR XENOGRAFTS

HERP1 Is a Cell Type-specific Primary Target of Notch

Identification and characterization of a mosquito-specific eggshell organizing factor in Aedes aegypti mosquitoes

Xanthine dehydrogenase‐1 silencing in Aedes aegypti mosquitoes promotes a blood feeding–induced adulticidal activity

Clinical features of freezing of gait in Parkinson's disease patients

Non‐ergot dopamine agonist therapy for Parkinson's disease in Japan: A claims database analysis

Differences in Parkinson's disease treatment between neurology and other departments in Japan

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