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Spatiotemporal Regulation of Signaling: Focus on T Cell Activation and the Immunological Synapse

International journal of molecular sciences, 2020-05, Vol.21 (9), p.3283

2020

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PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness

The Journal of cell biology, 2021-12, Vol.220 (12), p.1

2021

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PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity

Nature communications, 2016-04, Vol.7 (1), p.11366-11366, Article 11366

2016

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Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

Nature chemical biology, 2011-10, Vol.7 (12), p.942-949

2011

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The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

Nature cell biology, 2012-02, Vol.14 (2), p.148-158

2012

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Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119

The EMBO journal, 2012-10, Vol.31 (20), p.4085-4094

2012

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Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling

Science signaling, 2019-02, Vol.12 (567)

2019

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Identification of pyrazolopyridazinones as PDEδ inhibitors

Nature communications, 2016-04, Vol.7 (1), p.11360-11360, Article 11360

2016

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An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism

Nature communications, 2021-03, Vol.12 (1), p.1623-22, Article 1623

2021

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ARL3 activation requires the co-GEF BART and effector-mediated turnover

eLife, 2021-01, Vol.10

2021

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Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3

Biophysical journal, 2015-10, Vol.109 (8), p.1619-1629

2015

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ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition

American journal of human genetics, 2018-10, Vol.103 (4), p.612-620

2018

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The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism

Cell, 2010-05, Vol.141 (5), p.812-821

2010

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Efficacy and safety of sofosbuvir plus daclatasvir or ravidasvir in patients with COVID‐19: A randomized controlled trial

Journal of medical virology, 2021-12, Vol.93 (12), p.6750-6759

2021

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Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity

Nature communications, 2017-02, Vol.8 (1), p.14206-14206, Article 14206

2017

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Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells

AMB Express, 2020-03, Vol.10 (1), p.59-59, Article 59

2020

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The Engineer as Economist: Sewers and the Making of the Water Consumer in Colonial Cairo, 1890

Technology and culture, 2023-04, Vol.64 (2), p.434-455

Ismail, Shehab

2023

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A GDI/GDF-like system for sorting and shuttling ciliary proteins

Small GTPases, 2017-10, Vol.8 (4), p.208-211

Ismail, Shehab

2017

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Post‐proteomic identification of a novel phage‐encoded streptodornase, Sda1, in invasive M1T1 Streptococcus pyogenes

Molecular microbiology, 2004-10, Vol.54 (1), p.184-197

2004

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EPICURES AND EXPERTS: THE DRINKING WATER CONTROVERSY IN BRITISH COLONIAL CAIRO

Arab studies journal, 2018-10, Vol.26 (2), p.9-43

Ismail, Shehab

2018

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EPICURES AND EXPERTS: THE DRINKING WATER CONTROVERSY IN BRITISH COLONIAL CAIRO

Arab studies journal, 2018-10, Vol.26 (2), p.8-43

Ismail, Shehab

2018

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The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms

Biochemistry (Easton), 2021-06, Vol.60 (25), p.1952-1963

2021

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Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1

Structure (London), 2021-03, Vol.29 (3), p.226-237.e4

2021

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Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

Nature (London), 2013-05, Vol.497 (7451), p.638-642

2013

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CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

The Journal of cell biology, 2021-09, Vol.220 (9), p.1

2021

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Spatiotemporal Regulation of Signaling: Focus on T Cell Activation and the Immunological Synapse

PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness

PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119

Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling

Identification of pyrazolopyridazinones as PDEδ inhibitors

An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism

ARL3 activation requires the co-GEF BART and effector-mediated turnover

Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3

ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition

The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism

Efficacy and safety of sofosbuvir plus daclatasvir or ravidasvir in patients with COVID‐19: A randomized controlled trial

Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity

Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells

The Engineer as Economist: Sewers and the Making of the Water Consumer in Colonial Cairo, 1890

A GDI/GDF-like system for sorting and shuttling ciliary proteins

Post‐proteomic identification of a novel phage‐encoded streptodornase, Sda1, in invasive M1T1 Streptococcus pyogenes

EPICURES AND EXPERTS: THE DRINKING WATER CONTROVERSY IN BRITISH COLONIAL CAIRO

EPICURES AND EXPERTS: THE DRINKING WATER CONTROVERSY IN BRITISH COLONIAL CAIRO

The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms

Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1

Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

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