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Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

Cancer and metastasis reviews, 2009-06, Vol.28 (1-2), p.65-76

2009

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The benzylisoquinoline alkaloids, berberine and coptisine, act against camptothecin-resistant topoisomerase I mutants

Scientific reports, 2021-04, Vol.11 (1), p.7718-7718, Article 7718

2021

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Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

Cell stem cell, 2010-08, Vol.7 (2), p.225-239

2010

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Rotational Movement of the Formin mDia1 Along the Double Helical Strand of an Actin Filament

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6013), p.80-83

2011

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mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells

Molecular biology of the cell, 2008-05, Vol.19 (5), p.2328-2338

2008

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GDP-Bound Rab27a Dissociates from the Endocytic Machinery in a Phosphorylation-Dependent Manner after Insulin Secretion

Biological and Pharmaceutical Bulletin, 2019/09/01, Vol.42(9), pp.1532-1537

2019

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Citron kinase mediates transition from constriction to abscission through its coiled-coil domain

Journal of cell science, 2013-04, Vol.126 (Pt 8), p.1773-1784

2013

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Protective effect of hydrogen sulfide on pancreatic beta-cells

Nitric oxide, 2015-04, Vol.46, p.32-36

2015

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Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction

Cardiovascular research, 2021-03, Vol.117 (4), p.1103-1117

2021

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Baicalein disturbs the morphological plasticity and motility of breast adenocarcinoma cells depending on the tumor microenvironment

Genes to cells : devoted to molecular & cellular mechanisms, 2018-06, Vol.23 (6), p.466-479

2018

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IRR is involved in glucose-induced endocytosis after insulin secretion

Journal of pharmacological sciences, 2019-07, Vol.140 (3), p.300-304

2019

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ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles

The Journal of cell biology, 2005-03, Vol.168 (6), p.941-953

2005

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PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a

Journal of cell science, 2016-02, Vol.129 (3), p.637-649

2016

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GTP- and GDP-Dependent Rab27a Effectors in Pancreatic Beta-Cells

Biological and Pharmaceutical Bulletin, 2015/05/01, Vol.38(5), pp.663-668

2015

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Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

Nature cell biology, 1999-07, Vol.1 (3), p.136-143

1999

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Rho and anillin-dependent control of mDia2 localization and function in cytokinesis

Molecular biology of the cell, 2010-09, Vol.21 (18), p.3193-3204

2010

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Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

Science (American Association for the Advancement of Science), 1999-08, Vol.285 (5429), p.895-898

1999

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Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia

PloS one, 2011-09, Vol.6 (9), p.e25465

2011

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Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases

Molecular pharmacology, 2000-05, Vol.57 (5), p.976-983

2000

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Loss of a Rho-Regulated Actin Nucleator, mDia2, Impairs Cytokinesis during Mouse Fetal Erythropoiesis

Cell reports (Cambridge), 2013-11, Vol.5 (4), p.926-932

2013

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The Rho-mDia1 Pathway Regulates Cell Polarity and Focal Adhesion Turnover in Migrating Cells through Mobilizing Apc and c-Src

Molecular and Cellular Biology, 2006-09, Vol.26 (18), p.6844-6858

2006

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Conditional deficiency of Rho‐associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice

FEBS open bio, 2024-06, Vol.14 (6), p.906-921

2024

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A novel mRNA decay inhibitor abolishes pathophysiological cellular transition

Cell death discovery, 2022-06, Vol.8 (1), p.278-278, Article 278

2022

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Use and properties of ROCK-specific inhibitor Y-27632

Methods in Enzymology, 2000, Vol.325, p.273-284

2000

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Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop

The Journal of biological chemistry, 2000-02, Vol.275 (5), p.3577-3582

2000

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Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

The benzylisoquinoline alkaloids, berberine and coptisine, act against camptothecin-resistant topoisomerase I mutants

Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

Rotational Movement of the Formin mDia1 Along the Double Helical Strand of an Actin Filament

mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells

GDP-Bound Rab27a Dissociates from the Endocytic Machinery in a Phosphorylation-Dependent Manner after Insulin Secretion

Citron kinase mediates transition from constriction to abscission through its coiled-coil domain

Protective effect of hydrogen sulfide on pancreatic beta-cells

Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction

Baicalein disturbs the morphological plasticity and motility of breast adenocarcinoma cells depending on the tumor microenvironment

IRR is involved in glucose-induced endocytosis after insulin secretion

ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles

PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a

GTP- and GDP-Dependent Rab27a Effectors in Pancreatic Beta-Cells

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

Rho and anillin-dependent control of mDia2 localization and function in cytokinesis

Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia

Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases

Loss of a Rho-Regulated Actin Nucleator, mDia2, Impairs Cytokinesis during Mouse Fetal Erythropoiesis

The Rho-mDia1 Pathway Regulates Cell Polarity and Focal Adhesion Turnover in Migrating Cells through Mobilizing Apc and c-Src

Conditional deficiency of Rho‐associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice

A novel mRNA decay inhibitor abolishes pathophysiological cellular transition

Use and properties of ROCK-specific inhibitor Y-27632

Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop

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