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Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion

Cell, 2010-04, Vol.141 (1), p.117-128

2010

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Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions

Nature communications, 2018-11, Vol.9 (1), p.5121-17, Article 5121

2018

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p120-catenin binding masks an endocytic signal conserved in classical cadherins

The Journal of cell biology, 2012-10, Vol.199 (2), p.365-380

2012

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MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity

Science signaling, 2017-10, Vol.10 (503)

2017

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Exploring the evolution and function of Canoe's intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis

PloS one, 2023-08, Vol.18 (8), p.e0289224-e0289224

2023

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An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function

Nature cell biology, 2016-11, Vol.18 (11), p.1244-1252

2016

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Evolution of AF6-RAS association and its implications in mixed-lineage leukemia

Nature communications, 2017-10, Vol.8 (1), p.1099-13, Article 1099

2017

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Crystal structure of type I ryanodine receptor amino-terminal β-trefoil domain reveals a disease-associated mutation “hot spot” loop

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (27), p.11040-11044

2009

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Structural determination of the phosphorylation domain of the ryanodine receptor

The FEBS journal, 2012-10, Vol.279 (20), p.3952-3964

2012

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Structure-guided Mutation of the Conserved G3-box Glycine in Rheb Generates a Constitutively Activated Regulator of Mammalian Target of Rapamycin (mTOR)

The Journal of biological chemistry, 2014-05, Vol.289 (18), p.12195-12201

2014

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Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions

Cold Spring Harbor perspectives in biology, 2017-05, Vol.9 (5), p.a028738

2017

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A Conserved DpYR Motif in the Juxtamembrane Domain of the Met Receptor Family Forms an Atypical c-Cbl/Cbl-b Tyrosine Kinase Binding Domain Binding Site Required for Suppression of Oncogenic Activation

The Journal of biological chemistry, 2004-07, Vol.279 (28), p.29565-29571

2004

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An Autoinhibited Noncanonical Mechanism of GTP Hydrolysis by Rheb Maintains mTORC1 Homeostasis

Structure (London), 2012-09, Vol.20 (9), p.1528-1539

2012

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Myelin basic protein—diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis

Micron, 2004-01, Vol.35 (7), p.503-542

2004

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A Single Bifunctional UDP-GlcNAc/Glc 4-Epimerase Supports the Synthesis of Three Cell Surface Glycoconjugates in Campylobacter jejuni

The Journal of biological chemistry, 2005-02, Vol.280 (6), p.4792-4802

2005

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Monomeric α-catenin links cadherin to the actin cytoskeleton

Nature cell biology, 2013-03, Vol.15 (3), p.261-273

2013

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Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity

The Journal of biological chemistry, 2006-08, Vol.281 (34), p.24489-24495

2006

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Flagellin Glycosylation in Pseudomonas aeruginosa PAK Requires the O-antigen Biosynthesis Enzyme WbpO

The Journal of biological chemistry, 2008-02, Vol.283 (6), p.3507-3518

2008

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Structural Studies of Inositol 1,4,5-Trisphosphate Receptor

The Journal of biological chemistry, 2010-11, Vol.285 (46), p.36092-36099

2010

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The three-dimensional structure of the cadherin-catenin complex

Sub-cellular biochemistry, 2012, Vol.60, p.39

2012

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Structural and functional conservation of key domains in InsP3 and ryanodine receptors

Nature (London), 2012-01, Vol.483 (7387), p.108-112

2012

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Current and emerging therapies for Achondroplasia: The dawn of precision medicine

Bioorganic & medicinal chemistry, 2023-05, Vol.87, p.117275-117275, Article 117275

2023

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Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1,4,5-trisphosphate and ryanodine receptors

Biochimica et biophysica acta, 2015-09, Vol.1853 (9), p.1980-1991

2015

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Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain

Journal of molecular biology, 2020-01, Vol.432 (2), p.367-383

2020

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Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects

Cancer research (Chicago, Ill.), 2023-05, Vol.83 (9), p.1531-1542

2023

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Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions

p120-catenin binding masks an endocytic signal conserved in classical cadherins

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity

Exploring the evolution and function of Canoe's intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis

An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia

Crystal structure of type I ryanodine receptor amino-terminal β-trefoil domain reveals a disease-associated mutation “hot spot” loop

Structural determination of the phosphorylation domain of the ryanodine receptor

Structure-guided Mutation of the Conserved G3-box Glycine in Rheb Generates a Constitutively Activated Regulator of Mammalian Target of Rapamycin (mTOR)

Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions

A Conserved DpYR Motif in the Juxtamembrane Domain of the Met Receptor Family Forms an Atypical c-Cbl/Cbl-b Tyrosine Kinase Binding Domain Binding Site Required for Suppression of Oncogenic Activation

An Autoinhibited Noncanonical Mechanism of GTP Hydrolysis by Rheb Maintains mTORC1 Homeostasis

Myelin basic protein—diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis

A Single Bifunctional UDP-GlcNAc/Glc 4-Epimerase Supports the Synthesis of Three Cell Surface Glycoconjugates in Campylobacter jejuni

Monomeric α-catenin links cadherin to the actin cytoskeleton

Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity

Flagellin Glycosylation in Pseudomonas aeruginosa PAK Requires the O-antigen Biosynthesis Enzyme WbpO

Structural Studies of Inositol 1,4,5-Trisphosphate Receptor

The three-dimensional structure of the cadherin-catenin complex

Structural and functional conservation of key domains in InsP3 and ryanodine receptors

Current and emerging therapies for Achondroplasia: The dawn of precision medicine

Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1,4,5-trisphosphate and ryanodine receptors

Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain

Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects

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